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| 1 | 肝炎 E : 传染病学和预防显示文摘 Hepatitis E is caused by the hepatitis E virus (HEV), the major etiologic agent of enterically transmitted non-A hepatitis worldwide. HEV is responsible for major outbreaks of acute hepatitis in developing countries, especially in many parts of Africa and Asia. The HEV is a spherical, non-enveloped, single-stranded, positive sense RNA virus that is approximately 32 nm to 34 nm in diameter and is the only member in the family Hepeviridae and genus Hepevirus. There are four distinct genotypes of HEV (genotypes 1-4). While genotype 1 is predominantly associated with large epidemics in developing countries, genotype 3 has recently emerged as a significant pathogen in developed countries. The clinical manifestations and the laboratory abnormalities of hepatitis E are not distinguishable from that caused by other hepatitis viruses. However, high mortality among pregnant women particularly during the third trimester distinguishes HEV from other causes of acute viral hepatitis. Specific etiologic diagnosis among infected cases can be made by serological testing or detection of viral nucleic acid by reverse transcription polymerase chain reaction. Although there are vaccine candidates that had been shown to be safe and efficacious in clini-cal trials, none are approved currently for use. There is no specific therapy for acute hepatitis E as treatment remains supportive. | Eyasu H Teshale Dale J Hu | 2011 | World Journal of Hepatology2011，3，12： | 9 |
| 2 | Reversible in- hibitor of β-glucosidase 显示文摘 | DALE M P ENSLEY H E KERN K | 1985 | Biochemistry1985，24，： | 1 |
| 3 | True metabolizable ener- gy of fats at low level dietary inclusion 显示文摘 | DALE N M FALLER H L | 1982 | Poultry Science1982，61，12： | 1 |
| 4 | Improved assay for fecalcalprotectin显示文摘 | Ton H Brandsnes Dale S | 2000 | Clin Chim Acta2000，292，12： | 1 |
| 5 | Field performance of transgenic potato plants compared with controls regenerated from tuber discs and shoot cuttings显示文摘 | Dale P J Mcpartlan H C | 1992 | Theor Appl Genet1992，84，： | 1 |
| 6 | Respiratory health effects of home dampness and molds among Canadian children显示文摘 | Dales R E H Zwanenburg R Burnett | 1991 | Am J Epidemiol1991，134，： | 1 |
| 7 | Global change in forests:response of species,communities,and biomes显示文摘 | HANSEN A J NEILSON R P DALE V H | 2001 | Bioscionce2001，51，9： | 1 |
| 8 | Automatic continuity a survey显示文摘 | | 1978 | Bull London Math Soc1978，，10： | 1 |
| 9 | Improving protein solubility through rationally designed amino aeid replacemcnts: solubilization of the trimethoprim-resistant type S1 dihydrofolate reductase显示文摘 | Dale G E Broger C Langen H | 1994 | Protein Engineering Design and Selection1994，，7： | 1 |
| 10 | Epidemiology of ectopic pregnancy显示文摘 | Chow W H Daling J R Cates W | 1987 | Epidemiol Rev1987，9，： | 1 |
| 11 | Meningeal Carcinomatosis:Clinical Manifestations显示文摘 | Little JR Dale AJD Okazaki H | 1974 | Arch Neurol1974，30，2： | 1 |
| 12 | Improved assay for fecal calprotectin显示文摘 | Ton H Brandsnes O Dale S | 2000 | Clin Chim Acta2000，292，： | 1 |
| 13 | Field performance of transgenic potato compared with controls regenerated from tuber discs and shoot cutting显示文摘 | Dale P J McPartlan H C | 1992 | Theoretical Applied Genetics1992，84，： | 1 |
| 14 | Enhanced conversion of plant biomass into glucose using trangenic rice producted endoglucanase for cellulosic ethanol 显示文摘 | Oraby H Venkatesh B Dale B Ahmad R Ransom C Oehmke J Sticklen M | 2007 | Transgenic Res2007，16，： | 1 |
| 15 | Challenges in the Development and Use of Ecological Indicators显示文摘 | Dale V H Beyeler S C | 2001 | Ecological Indicators2001，1，： | 1 |
| 16 | Epidemiology of ectopic pregnancy 显示文摘 | Chow W H Daling J R Cates W Jr | 1987 | Epidemiol Rev1987，9，3： | 1 |
| 17 | Competition in the third millennium efficiency or effectiveness 显示文摘 | SHELBY D H DALE F D | 2002 | Journal of Business Research2002，，55： | 1 |
| 18 | Management of middle turbinate in endoscopic sinus surgery operative technology显示文摘 | DALE H RICE N D | 1995 | Otolaryngol Head Neck Surg1995，112，2： | 1 |
| 19 | Risk tolerance and asset allocation for investors nearing retirement 显示文摘 | Govind H Kenneth S C Dale L D | 2000 | Financial Services Review2000，，9： | 1 |
| 20 | Effects of ammonia fiber explosion treatment on activity of endoglucanase from Acidothermus cellulolyticus in transgenic plant 显示文摘 | Teymouri F Alizadeh H Laureano-Perez L Dale B Sticklen M | 2004 | Appl Biochem Biotechnol2004，116，： | 1 |
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