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| 1 | Quantum-mechanical results for a free particle inside abox with general boundary conditions显示文摘 | Da Luz M G E Cheny Bin Kany | 1995 | Phys Rev1995，51，3： | 1 |
| 2 | Endurance exercise training ameliorates insulin resist- ance and reticulum stress in adipose and hepatic tissue in obese rats显示文摘 | da Luz G | 2011 | Eur J Appl Physiol2011，111，： | 1 |
| 3 | Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder 显示文摘 | Dias G P Bevilaqua M C da Luz A C | 2014 | Behav Brain Res2014，15，263： | 1 |
| 4 | Improvements in the statistical approach to random Lévy flight searches显示文摘 | da Luz M G E Buldyrev S V Havlin S | 2001 | Physica A:Statistical Mechanics and Its Applications2001，295，12： | 1 |
| 5 | Endurance exercise training ameliorates insulin resistance and reticulum stress in adipose and hepatic tissue in obese rats显示文摘 | DA LUZ G FREDERICO M J S DA SILVA S | 2011 | Eur J Appl Physiol2011，111，9： | 1 |
| 6 | Dentoskeletal effects of maxillary protraction in cleft patients with repetitive weekly protocol of alternate rapid maxillary expansions and constrictions显示文摘 | da Luz Vieira G de Menezes LM de Lima EM | | 0，，04： | 1 |
| 7 | Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4alpha pathway in insulin resistant mice显示文摘 | De Souza C T Frederico M J da Luz G | | 0，，12： | 1 |
| 8 | Dentoskeletal effects of maxillary protraction in cleft patients with repetitive weekly protocol of alternate rapid maxillary expansions and constrictions显示文摘 | da Luz Vieira G de Menezes LM de Lima EM | 2009 | Cleft Palate Craniofac J2009，46，4： | 1 |
| 9 | Dentoskeletal effects of maxillary protraction in cleft pa- tients with repetitive weekly protocol of alternate rapid maxillary expansions and constrictions 显示文摘 | da Luz Vieira G de Menezes LM de Lima EM | 2009 | Cleft Palate Craniofac J2009，46，4： | 1 |
| 10 | Dentoskeletal effects of maxillary protraction in cleft pa- tients with repetitive weekly protocol of alternate rapid maxillary expansions and constrictions 显示文摘 | Da Luz Vieira G de Menezes LM de Lima EM | 2009 | Cleft Palate Craniofac J2009，，4： | 1 |
| 11 | Dentoskeletal effects of maxillary protraction in cleft pa- tients with repetitive weekly protocol of alternate rapidmaxillary expansions and constrictions 显示文摘 | da Luz Vieira G de Menezes L M de Lima E M | 2009 | Cleft Palate Craniofac2009，46，4： | 1 |
| 12 | Risk factors associated with inflammatory bowel disease: A multicenter case-control study in Brazil显示文摘BACKGROUND The etiology of inflammatory bowel disease(IBD)is unknown,but it is believed to be multifactorial.The hygiene hypothesis proposes that better hygiene conditions would lead to less infectious disease during childhood and favor the development of immune-mediated diseases.AIM To test the hygiene hypothesis in IBD by assessing the environmental risk factors associated with IBD development in different regions of Brazil with diverse socioeconomic development indices.METHODS A multicenter case-control study was carried out with 548 Crohn’s disease(CD)and 492 ulcerative colitis(UC)outpatients and 416 healthy controls,from six IBD centers within different Brazilian states at diverse socioeconomic development stages.A semi-structured questionnaire with 87 socioeconomic and environmental questions was applied.Logistic regression model was created to assess the odds ratio(OR)with P value and 95%confidence intervals(CI).RESULTS Predictive variables for both diseases(CD and UC)were women[odd ratios(OR)=1.31;OR=1.69],low monthly family income(OR=1.78;OR=1.57),lower number of cohabitants(OR=1.70;OR=1.60),absence of vaccination(OR=3.11;OR=2.51),previous history of bowel infections(OR=1.78;OR=1.49),and family history of IBD(OR=5.26;OR=3.33).Associated risk factors for CD were age(18-39 years)(OR=1.73),higher educational level(OR=2.22),absence of infectious childhood diseases(OR=1.99).The UC predictive variables were living in an urban area(OR=1.62),inadequate living conditions(OR=1.48)and former smokers(OR=3.36).Appendectomy was a risk factor for CD(OR=1.58)with inverse association with UC(OR=4.79).Consumption of treated and untreated water was associated with risk of CD(OR=1.38)and UC(OR=1.53),respectively.CONCLUSION This is the first examining environmental exposures as risk factors for inflammatory bowel disease in Brazil.Most of the variables associated with disease risk support the role of the hygiene hypothesis in IBD development. | Valéria Cristina Loureiro Salgado Ronir Raggio Luiz Neio Lucio Fernandes Boéchat Isabella Sued Leao Bianca do Carmo Schorr JoséMiguel Luz Parente Daniela Calado Lima Eduardo Santos Silveira Júnior Genoile Oliveira Santana Silva Neogélia Pereira Almeida Andrea Vieira Maria Luiza Queiroz de Bueno Júlio Maria Chebli érika Ruback Bertges Luísa Martins da Costa Brugnara Columbano Junqueira Neto Stefania Burjack Gabriel Campbell Luana Letiza Discacciati Joao Paulo Silva Cézar Tiago Nunes Gilaad G Kaplan Cyrla Zaltman | 2020 | World Journal of Gastroenterology2020，26，25： | 1 |
| 13 | Inter-observer reliability of ultrasonography in the assessment of carti- lage damage in rheumatoid arthritis 显示文摘 | Filippucci E Da Luz K R Di G L | 2010 | Ann Rheum Dis2010，69，10： | 1 |
| 14 | Dentoskeletal effects of maxillay protraction in cleft patients with repetitive weekly protocol of alternate rapid maxillay expansions and constrictions显示文摘 | da Luz Vieira G de Menezes LM de Lima EM | | 0，，04： | 1 |
| 15 | Exercise training reduces insulin resistance and upregulates the mTOR/p70S6k pathway in cardiac muscle of diet-induced obesity rats 显示文摘 | Medeiros C Frederico M J da Luz G | 2011 | J Cell Physio12011，226，3： | 1 |
| 16 | Exercise training reduces insulin resistance and up regulates the mTOR/ p70S6k pathway in cardiac muscle of diet-induced obesity rats 显示文摘 | Medeiros C Frederico M J da Luz G | 2010 | J Cell Physiol2010，226，3： | 1 |
| 17 | Electrical characteristics in unipolar conjugated polymer devices:the case of modified transport properties in the neighbourhood of the top electrode/polymer interface显示文摘 | KOEHLER M DA LUZ M G E HUMMELGEN I A | 2001 | J Phys D:Appl Phys2001，34，1： | 1 |
| 18 | Translational findings on brain-derived neurotrophic factor and anxiety:contributions from basic research to clinical practice显示文摘 | Domingos da Silveira da Luz AC Pereira Dias G do Nascimento Bevilaqua MC | 2013 | Neuropsychobiology2013，68，3： | 1 |
| 19 | Real-world treatment patterns and disease control over one year in patients with inflammatory bowel disease in Brazil显示文摘BACKGROUND Crohn’s disease(CD)and ulcerative colitis(UC)are inflammatory bowel diseases(IBDs)with a remission-relapsing presentation and symptomatic exacerbations that have detrimental impacts on patient quality of life and are associated with a high cost burden,especially in patients with moderate-to-severe disease.The Real-world Data of Moderate-to-Severe Inflammatory Bowel Disease in Brazil(RISE BR)study was a noninterventional study designed to evaluate disease control,treatment patterns,disease burden and health-related quality of life in patients with moderate-to-severe active IBD.We report findings from the prospective follow-up phase of the RISE BR study in patients with active UC or CD.AIM To describe the 12-mo disease evolution and treatment patterns among patients with active moderate-to-severe IBD in Brazil.METHODS This was a prospective,noninterventional study of adult patients with active Crohn’s disease(CD:Harvey-Bradshaw Index≥8,CD Activity Index≥220),inadequate CD control(i.e.,calprotectin>200μg/g or colonoscopy previous results),or active ulcerative colitis(UC:Partial Mayo score≥5).Enrollment occurred in 14 centers from October 2016 to February 2017.The proportion of active IBD patients after 9-12 mo of follow-up,Kaplan-Meier estimates of the time to mild or no activity and a summary of treatment initiation,discontinuation and dose changes were examined.RESULTS The study included 118 CD and 36 UC patients,with mean±SD ages of 43.3±12.6 and 44.9±16.5 years,respectively.The most frequent drug classes at index were biologics for CD(62.7%)and 5-aminosalicylate derivates for UC patients(91.7%).During follow-up,65.3%of CD and 86.1%of UC patients initiated a new treatment at least once.Discontinuations/dose changes occurred in 68.1%of CD patients[median 2.0(IQR:2-5)]and 94.3%of UC patients[median 4.0(IQR:3-7)].On average,CD and UC patients had 4.4±2.6 and 5.0±3.3 outpatient visits,respectively.The median time to first mild or no activity was 319(IQR:239-358)d for CD and 320(IQR:288-358)d for UC patients.At 9-12 mo,22.0%of CD and 20.0%of UC patients had active disease.CONCLUSION Although a marked proportion of active IBD patients achieved disease control within one year,the considerable time to achieve this outcome represents an unmet medical need of the current standard of care in a Brazilian real-world setting. | Ligia Yukie Sassaki Sender J Miszputen Roberto Luiz Kaiser Junior Wilson R Catapani Mauro Bafutto António S Scotton Cyrla Zaltman Julio Pinheiro Baima Hagata S Ramos Mikaell Alexandre Gouvea Faria Carolina D Gonçalves Isabella Miranda Guimaraes Cristina Flores Heda M B S Amarante Rodrigo Bremer Nones JoséMiguel Luz Parente Murilo Moura Lima Júlio Maria Chebli Maria de Lourdes Abreu Ferrari Julia F Campos Maria G P Sanna Odery Ramos Rogério Serafim Parra Jose J R da Rocha Omar Feres Marley R Feitosa Rosana Fusaro Caratin Juliana Tosta Senra Genoile Oliveira Santana | 2021 | World Journal of Gastroenterology2021，27，23： | 0 |
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