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| 1 | Effects of CeO_2 doping on the structure and properties of PSN-PZN-PMS-PZT piezoelectric ceramics显示文摘Quinary system piezoelectric ceramics PSN-PZN-PMS-PZT were prepared by using a two-step method. The ef-fects of CeO2 doping on piezoelectric and dielectric properties of the system were investigated at morphotropic phaseboundary (MPB). The results reveal that the relative dielectric constant εT33 /ε0,the Curie temperature Tc ,the piezoelectricconstant d33, the mechanical quality factor Qm,, and the electromechanical coupling coefficient Kp are changed with the in-crease of CeO2 content. On the other hand, the effects of CeO2 doping on the dielectric properties of PSN-PZN-PMS-PZTpiezoelectric ceramics at high electric field are consistent with the change at weak electric field. The values of dielectricconstant and dielectric loss are enhanced with the increasing of electric field. | SUN Qingchi LU Cuimin ZHOU Hua | 2005 | Rare Metals2005，24，3： | 3 |
| 2 | Exposure to Prorocentrum minimum Induces Oxidative Stress and Apoptosis in the Ridgetail White Prawn, Exopalaemon carinicauda显示文摘Prorocentrum minimum is a bloom-forming, planktonic mixotrophic dinoflagellate, and can cause stress in shrimp ponds. In this study, healthy Exopalaemon carinicauda were exposed to 5 × 10^4 cells mL^-1 P. minimum for 72 hours to investigate the adverse effect of P. minimum on shrimps. Elevated superoxide dismutase(SOD) activity and malondialdehyde(MDA) content, reduced total antioxidant capacity(T-AOC) and catalase(CAT) activity, and regulatory glutathione peroxidase(GPX) activity were found in the hemolymph of E. carinicauda after exposure to P. minimum. In this study, P. minimum exposure induced oxidative stress and caused significant oxidative damage to E. carinicauda. P. minimum exposure increased the expression of HSP70 gene in the hemocyte, gills and hepatopancreas. Compared with the enhanced level of caspase-3 gene mR NA in the hemocyte and gills, the up-regulation of caspase-3 gene in the hepatopancreas was only observed from 3 to 6 h, and then the mRNA level of glutathione-S-transferase(GST) gene increased. These results indicated that GST might be involved in the shrimp hepatopancreas’ defense against P. minimum exposure. The present study demonstrates that exposure to P. minimum could induce oxidative stress and apoptosis in E. carinicauda. The SOD activity, HSP70 and GST(in the hepatopancreas) were evoked to protect cells from oxidative stress and apoptosis. This study will provide new insights into the toxic mechanism of P. minimum on shrimps. | MU Cuimin GE Qianqian LI Jian | 2019 | Journal of Ocean University of China2019，18，3： | 2 |
| 3 | Antioxidant Response of Ridgetail White Prawn Exopalaemon carinicauda to Harmful Dinoflagellate Prorocentrum minimum Exposure and Its Histological Change显示文摘The dinoflagellate Prorocentrum minimum,one of the most widespread red tide causing species,affects marine aquaculture and ecosystems worldwide.In this study,ridgetail white prawn Exopalaemon carinicauda were exposed to P.minimum cells(5 × 104 cells mL-1) to investigate its harmful effects on the shrimp.Antioxidant activities and histological changes were used as indicators of health status of the shrimp.In 72 hours,the mortality of E.carinicauda was not affected,but its antioxidant response and histology were statistically different from those of control.Elevated superoxide dismutase(SOD) and glutathione peroxidase(GPX) activities and depressed catalase(CAT) activity were observed in gill;while increased SOD,glutathione S-transferase(GST),CAT activities and modulated GPX activity were observed in hepatopancreas.Thus,antioxidant activities in gill and hepatopancreas seem to respond differentially to harmful alga exposure.Increased malondialdehyde(MDA) content in early a few hours indicates the damage of the antioxidant defense system.Although MDA content recovered to a low level thereafter,a series of histological abnormalities including accumulation or infiltration of hemocytes,tissue lesions and necrosis were discovered in gill and hepatopancreas.Exposure to P.minimum induced sublethal effects on E.carinicauda,including temporary oxidative damage and histological injury. | MU Cuimin REN Xianyun GE Qianqian WANG Jiajia LI Jian | 2017 | Journal of Ocean University of China2017，16，2： | 2 |
| 4 | Formation Rule for Al-based Ternary Quasi-crystals: Example for Al-Ni-Fe Decagonal Phase显示文摘 | Qiang Jianbing Wang Dehe Bao Cuimin | 2001 | J Mater Res2001，16，9： | 1 |
| 5 | DBT parameters and dynamic monitoring during reservoir development, and distribution region prediction of remaining oil:A case study on the Sha-3~3 oil reservoir in the Liubei region, Nanpu sag显示文摘In this study, compositional characteristics of crude oil, including the variation of aliphatic, aromatic and pyrrolic nitrogen compounds, were systematically monitored and investigated in a high water-cut oil reservoir over a short time.The results showed that among the widely used parameters indicative of oil maturity and migration, tetramethyl/monomethyl DBT and tricyclic terpane/(tricyclic terpane+C30 hopanoid) varied remarkably, and a positive correlation was observed between these two parameters.The variation of each of these parameters during waterflooding development was correlated with the flow effect of crude promoted by the water drive in oil reservoirs.A solid consistency was observed among the results of numerical simulation and development; the direction and pathway of waterflooding crude was indicated by Tetramethyl/monomethyl DBT, and the distribution region prediction of remaining oil hereby obtained.Therefore, these two parameters could be used as molecular tracers for the oil during waterflooding.This study would be of practical significance for geochemical dynamic monitoring and reservoir development. | XU YaoHui WANG TieGuan CHEN NengXue YANG CuiMin WANG QiaoLi | 2012 | Science China Earth Sciences2012，55，12： | 1 |
| 6 | Immune Response of the Ridgetail White Prawn Exopalaemon carinicauda After Exposure to the Dinoflagellate Prorocentrum minimum显示文摘The dinoflagellate Prorocentrum minimum is known to affect the normal physiological function of Exopalaemon carinicauda by inducing oxidative stress,apoptosis,and cellular injury.To study the effects of P.minimum on the immune defense system of shrimp,E.carinicauda were exposed to 5×10^(3)cells mL^(-1)and 5×10^(4)cells mL^(-1)of P.minimum for 336 h in treatment groups,while E.carinicauda cultured in filtered seawater was employed as control.The total hemocyte counts(THC),hemocyanin concentration(HEM),and the activity of alkaline phosphatase(AKP)in hemolymph serum,as well as expressions of six immunity-related genes in hemocytes,hepatopancreases and gills were determined.The exposure of P.minimum significantly reduced the THC,HEM concentration and AKP activity in hemolymph serum.Immunity-related genes expressed differently in hemocytes,hepatopancreases and gills.Compared with the control group,the expressions of Crustin and pro PO in hemocytes were significantly up-regulated in the treatment groups,while the up-regulated expressions of LGBP,Lysozyme and Serpin were only found in the group exposed to 5×10^(4)cells mL^(-1)of P.minimum.In the gills of E.carinicauda exposed to P.minimum,the down-regulation of ALF,proPO and Serpin,up-regulation of LGBP and Lysozyme,as well as unaffected Crustin were observed.In hepatopancreases,the up-regulated expressions of LGBP,Crustin,Lysozyme,Serpin and proPO(only in 5×10^(3)cells mL^(-1)of P.minimum group)were found in the treatment groups.After exposure to P.minimum for 336 h,shrimps were injected with Vibrio parahaemolyticus and WSSV.The results showed that the mortality rates of shrimp in the treatment groups were significantly increased with a dose-dependent effect,which suggests that exposure to P.minimum may reduce the immunity of E.carinicauda.The research indicates that hemocytes and hepatopancreases play important roles in protecting the shrimp immune response to harmful algae,while the protection effect of hemolymph serum and gills may be suppressed.Since the exposure to P.minimum depressed the immunity of E.carinicauda,further studies are needed to confirm whether the presence of the algae will affect the susceptibility of shrimp to pathogens. | MU Cuimin REN Xianyun LI Jian | 2023 | Journal of Ocean University of China2023，22，3： | 1 |
| 7 | Lipid produc- tion from Jerusalem artichoke by Rhodosporidium toruloides Y4 显示文摘 | ZHAO Xin WU Siguo HU Cuimin | 2010 | J Ind Microbiol Biotechnol2010，37，6： | 1 |
| 8 | 显示文摘 | ZhangWeijia(张唯佳) WangTianmin(王天民) ZhongLizhi(钟立志) WuXiaowen(吴小文) CuiMin(崔敏) | | 物理学报0，54，9： | 1 |
| 9 | Evaluation of reservoir connectivity using whole-oil gas chromatographic fingerprint technology: A case study from the Es_3~3 reservoir in the Nanpu Sag, China显示文摘In this study, whole-oil gas chromatographic fingerprint analyses were performed on oils from the Es33 reservoir in the Liubei area of the Nanpu Sag. The gas chromatographic peaks of cyclic and branched alkanes with relatively high resolution from nC10 to nC25 were selected to establish a database of whole-oil gas chromatographic peak height ratio fingerprints. Reservoir fluid connectivity was identified by using clustering analysis. This method can reflect the gas chromatography fingerprint information accurately and entirely, and avoid the one-sidedness of the star diagram method which only selects several fixed gas chromatographic peaks. | Xu Yaohui Shen Xianda Chen Nengxue Yang Cuimin WangQiaoli | 2012 | Petroleum Science2012，9，3： | 1 |
| 10 | Net annual global warming potential and greenhouse gas intensity in Chinese double rice-cropping systems: a 3-year field measurement in long-term fertilizer experiments显示文摘 | Shang Qingyin Yang Xiuxia Gao Cuimin | 2011 | Global Change Biology2011，17，6： | 1 |
| 11 | Influenceandmechanismofsurfactantsonviscosityreductioneffectofoil-solubleviscositydepressant(表面活性剂对油溶性降黏剂降黏效果的影响及作用机制)显示文摘 | CUIMin(崔敏) LIChuan(李传) WENPing(文萍) etal | 2013 | 中国石油大学报(自然科学版)2013，37，3： | 1 |
| 12 | Application of multi - linear regress analysis to predict Beijing urban domestic water demand 显示文摘 | Zhang Yajun Liu Quansheng Feng Cuimin | 2003 | Water & Waste Water2003，29，4： | 1 |
| 13 | A polymorphism at the miR-502 binding site in the 3’ untranslated regionof the SET8 gene is associated with the outcome of small-cell lung cancer显示文摘 | Cuimin Ding Ruijuan Li Jingcui Peng Shengmian Li Zhanjun Guo | 2012 | Experimental and Therapeutic Medicine2012，，4： | 1 |
| 14 | A Comparative Analysis of Environmental Courts in Sweden and China显示文摘 | Cuimin Wang | 2016 | Fudan Journal of the Humanities and Social Sciences2016，9，4： | 0 |
| 15 | Prognostic factors for patients with limited-stage small-cell lung cancer without receiving prophylactic cranial irradiation显示文摘Objective:This retrospective study aims to explore the risk factors for brain metastasis and the prognostic factors for overall survival(OS)in patients with limited-stage small-cell lung cancer(LS-SCLC)who have no brain metastases according to magnetic resonance imaging(MRI)and have not received prophylactic cranial irradiation(PCI)after first-line chemoradiotherapy.Methods:A total of 107 patients who were treated in the Fourth Hospital of Hebei Medical University from January 2013 to December 2017 were enrolled in this study.The patients were treated with etoposide/platinum chemotherapy and thoracic radiotherapy(TRT)with involved-field irradiation.The median dose of the radiotherapy was 60 Gy(50-64 Gy).The primary study endpoints include BMFS(brain-metastasis-free survival)and OS(overall survival).The Kaplan-Meier method was applied to estimate survival,with a log-rank test used to ascertain statistical significance.The multivariate Cox proportional hazards model was used to determine the prognostic factors for survival.Results:The median follow-up of all patients was 18.8 months(range:7.9–65.1 months)and the median follow-up of surviving patients was 26.7 months(range:18.8–65.1 months).The median OS of the whole cohort was 20.1 months,and the 1-,2-and 3-year OS rates were 84.9%,44.9%,and 25.9%,respectively.The 1-,2-,and 3-year BMFS rates were 69.0%,49.9%,and 40.7%,respectively.50 patients(46.7%)developed brain metastases during the follow-up period,and the median time from the start to brain metastasis was 10.7 months(range:4.8–31.1 months).As shown by multivariate analysis,independent prognostic factors of OS included cycles of chemotherapy(P=0.019),the response to initial treatment(P=0.011),and the start time of TRT(P=0.044).The independent prognostic factors of BMFS included the clinical stage(P=0.008),the response to initial treatment(P=0.024),and the start time of TRT(P=0.028).Conclusions:For patients with LS-SCLC who have not received PCI,favorable factors for lower brain metastasis and higher survival include early clinical stage,CR to initial chemoradiotherapy,early TRT,and adequate cycles of chemotherapy.PCI is still recommended as the standard modality since the incidence of brain metastases was high(46.7%). | Cuimin Ding Jing Li Shuoshuo Wang Chen Yang Rui Zhang Wenwen Bai Ming Liu Chanjun Zhen Xueying Qiao | 2020 | Radiation Medicine and Protection2020，1，2： | 0 |
| 16 | Protomer Roles in Chloroplast Chaperonin Assembly and Function显示文摘三叶绿体 CPN60 protomers (CPN60, CPN601,和 CPN602 ) 的单个角色并且他们是否并且怎么被装配进功能的 chaperonin 建筑群在 Chlamydomonas reinhardtii 被调查。包含所有三个潜在的子单元的蛋白质建筑群在 Chlamydomonas 被识别,并且他们在 Escherichia coli 的合作表示产出包含所有三个子单元(CPN6012 ) 的 oligomers 的一张同类的人口,与与 tetradecameric 结构一致的分子的重量。当 CPN60 的 homo-oligomers 能形成时,当 CPN60 是在场的, CPN602 的 homo-oligomers 乐意地面对 ATP 和另外的 protomers 被变成 hetero-oligomers 时,他们戏剧性地被减少。ATP 水解作用引起了 CPN60 oligomers 拆卸并且驱使净化的 protomers 重新组成 oligomers invitro,建议 CPN60 oligomers 的动态性质依赖于 ATP。在 5:6:3 比率的仅仅 hetero-oligomeric CPN6012,包含的 CPN60, CPN601,和 CPN602 子单元,与 GroES 机能上地合作了。CPN60 和 CPN60 子单元的联合,然而并非单个子单元在有子单元识别的 E.coli 的独自一个的、补充 GroEL 功能特性。在 Chlamydomonas 的 CPN60 子单元的下面规定导致了一个慢生长缺点和无能自造营养物质地成长,显示 CPN60 invivo 的必要角色。 | Cuicui Bai Peng Guo Qian Zhao Zongyang Lv Shijia Zhang Fei Gao Liyan Gao Yingchun Wang Zhixi Tian Jifeng Wang Fuquan Yang Cuimin Liu | 2015 | Molecular Plant2015，8，10： | 0 |
| 17 | Focus on the Learner显示文摘Language teaching is often discussed from the point of view of the teacher. Some of the ways in which teachers beliefs, goals, attitudes, and decisions influence how theyapproach of teaching have already been examined by many people. However, while learning is the goal of teaching, it is not necessarily the mirror image of teaching. Learners, too,bring to learning their own beliefs, goals, attitudes, | CuiMin | 2004 | 中国英语教学:英文版2004，27，3： | 0 |
| 18 | Biomaterials-based anti-inflammatory treatment strategies for Alzheimer's disease显示文摘The current therapeutic drugs for Alzheimer's disease only improve symptoms,they do not delay disease progression.Therefo re,there is an urgent need for new effective drugs.The underlying pathogenic factors of Alzheimer's disease are not clear,but neuroinflammation can link various hypotheses of Alzheimer's disease;hence,targeting neuroinflammation may be a new hope for Alzheimer's disease treatment.Inhibiting inflammation can restore neuronal function,promote neuro regeneration,reduce the pathological burden of Alzheimer's disease,and improve or even reverse symptoms of Alzheimer's disease.This review focuses on the relationship between inflammation and various pathological hypotheses of Alzheimer's disease;reports the mechanisms and characteristics of small-molecule drugs(e.g.,nonsteroidal anti-inflammatory drugs,neurosteroids,and plant extracts);macromolecule drugs(e.g.,peptides,proteins,and gene therapeutics);and nanocarriers(e.g.,lipid-based nanoparticles,polymeric nanoparticles,nanoemulsions,and inorganic nanoparticles)in the treatment of Alzheimer's disease.The review also makes recommendations for the prospective development of anti-inflammatory strategies based on nanocarriers for the treatment of Alzheimer's disease. | Jianjian Chu Weicong Zhang Yan Liu Baofeng Gong Wenbo Ji Tong Yin Chao Gao Danqi Liangwen Mengqi Hao Cuimin Chen Jianhua Zhuang Jie Gao You Yin | 2024 | Neural Regeneration Research2024，19，1： | 0 |
| 19 | Structural insights into the functions of Raf1 and Bsd2 in hexadecameric Rubisco assembly显示文摘Hexadecameric formI Rubisco,which consisting consists of eight large(RbcL)and eight small(RbcS)subunits,is the most abundant enzyme on earth.Extensive efforts to engineer an improved Rubisco to speed up its catalytic efficiency and ultimately increase agricultural productivity.However,difficulties with correct folding and assembly in foreign hosts or in vitro have hampered the genetic manipulation of hexadecameric Rubisco.In this study,we reconstituted Synechococcus sp.Pcc6301 Rubisco in vitro using the chaperonin system and assembly factors from cyanobacteria and Arabidopsis thaliana(At).Rubisco holoenzyme was produced in the presence of cyanobacterial Rubisco accumulation factor 1(Raf1)alone or both AtRaf1 and bundle-sheath defective-2(AtBsd2)from Arabidopsis.RbcL released from GroEL is assembly capable in the presence of ATP,and AtBsd2 functions downstream of AtRaf1.Cryo-EM structures of RbcL8-AtRaf18,RbcL8-AtRaf14-AtBsd2s,and RbcLs revealed that the interactions between RbcL and AtRaf1 are looser than those between prokaryotic RbcL and Raf1,with AtRaf1 tilting 7°farther away from RbcL.AtBsd2 stabilizes the flexible regions of RbcL,including the N and C termini,the 60s loop,and loop 6.Using these data,combined with previous findings,we propose the possible biogenesis pathways of prokaryotic and eukaryotic Rubisco. | Ran Wang Hui Song Wenjuan Zhang Ning Wang Shijia Zhang Ruiqi Shao Cuimin Liu | 2023 | Molecular Plant2023，16，12： | 0 |
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