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| 1 | WJBC 5^(th) Anniversary Special Issues(2): Proteomics In 2014, can we do better than CA125 in the early detection of ovarian cancer?显示文摘Ovarian cancer is a lethal gynecologic malignancy with greater than 70% of women presenting with advanced stage disease. Despite new treatments, long term outcomes have not significantly changed in the past 30 years with the five-year overall survival remaining between 20% and 40% for stage Ⅲ and Ⅳ disease. In contrast patients with stage Ⅰ disease have a greater than 90% five-year overall survival. Detection of ovarian cancer at an early stage would likely have significant impact on mortality rate. Screening biomarkers discovered at the bench have not translated to success in clinical trials. Existing screening modalities have not demonstrated survival benefit in completed prospective trials. Advances in high throughput screening are making it possible to evaluate the development of ovarian cancer in ways never before imagined. Data in the form of human '-omes' including the proteome, genome, metabolome, and transcriptome are now available in various packaged forms. With the correct pooling of resources including prospective collection of patient specimens, integration of high throughput screening, and use of molecular heterogeneity in biomarker discovery, we are poised to make progress in ovarian cancer screening. This review will summarize current biomarkers, imaging, and multimodality screening strategies in the context of emerging technologies. | Joshua G Cohen Matthew White Ana Cruz Robin Farias-Eisner | 2014 | World Journal of Biological Chemistry2014，5，3： | 18 |
| 2 | Laparoscopy-assisted versus open colectomy for treatment of colon cancer in the elderly: morbidity and mortality outcomes in 545 patients显示文摘 | Francesc Vallribera Valls Filippo Landi Eloy Espín Basany José Luis Sánchez García Luis Miguel Jiménez Gómez Marc Martí Gallostra Luis Salgado Cruz Manuel Armengol Carrasco | 2014 | Surgical Endoscopy2014，，12： | 2 |
| 3 | Studies on the extraction and composition of rice protein显示文摘 | Cruz L J Espiritu S G | 1966 | Cereal Chem1966，43，： | 1 |
| 4 | The impact of lung recruitment on hemodynamics during one-lung ventilation 显示文摘 | Garutti I Martinez G Cruz P | 2009 | Cardiothorac Vasc Anesth2009，23，4： | 1 |
| 5 | Biomechanical comparison of unipedicular versus bipedicular kyphoplasty显示文摘 | Steinmann J Tingey CT Cruz G | 2005 | Spine2005，30，2： | 1 |
| 6 | Plasma vitamins, amino acids, and renal function in postexercise hyperhomocysteinemia 显示文摘 | VENTA R CRUZ E VALCARCEL G | 2009 | Med Sci Sports Exerc2009，41，8： | 1 |
| 7 | Popliteal artery entrapment syndrome in an elite rower: sonographie appearances 显示文摘 | Alvarez Rey I Alvarez Rey G Alvero Cruz JR | 2004 | J Ultrasound Med2004，23，12： | 1 |
| 8 | Effect of the inoculation level of Lactobacillus acidophilus in probiotic cheese on the physicochemical features and sensory performance compared with commercial cheeses显示文摘 | GOMES A A BRAGA S P CRUZ A G | 2011 | Journal of Dairy Science2011，94，： | 1 |
| 9 | Fine-tuning of the piping model through small-scale,medium-scale and ijkdijk experiments 显示文摘 | SELLMEIJER J B LOPEZ de LA CRUZ J van BEEK V M KNOEFF J G | 2011 | European Journal of Environmental and Civil Engineering2011，15，8： | 1 |
| 10 | Biomechanical comparison of unipedieular versus bipedicular kyphoplasty 显示文摘 | STEINMANN J TINGEY C T CRUZ G etal | 2005 | Spine2005，30，2： | 1 |
| 11 | Studies on the extraction and composition of rice protein 显示文摘 | Cagampang G B Cruz L J Espiritu S G | 1966 | Cereal Chem1966，43，： | 1 |
| 12 | Probiotic DairyProducts as Functional Foods显示文摘 | GRANATO D BRANCO G F CRUZ A G | 2010 | Comprehensive Reviews in FoodScience and Food Safety2010，9，5： | 1 |
| 13 | Biomechanical comparison of unipedicular versus bipedicular kyphoplasty 显示文摘 | Steinmann J Tingey CT Cruz G | 2005 | Spine2005，30，2： | 1 |
| 14 | Preparation of MoS2 and WS2 catalysts by in situ decomposition of ammonium thiosalts显示文摘 | Alonso G Del Valle M Cruz J Petranovskii V LiceaClaverie A Fuentes S | | 0，，： | 1 |
| 15 | MR imaging findings in 56 patients with wernicke encephalopathy:nonalcoholics may differ from alcoholics显示文摘 | Zuccoli G Santa Cruz D Bertolini M | 2009 | AJNR Am J Neuroradiol2009，30，1： | 1 |
| 16 | A wavelet-based image fusion tutorial显示文摘 | Pajares G Cruz J M | | 0，，09： | 1 |
| 17 | Quality Assurance Re- quirements in Produce Processing 显示文摘 | DA CRUZ G CENCI A & MAIA A | 2006 | Trends in Food Science & Technology2006，17，8： | 1 |
| 18 | Determining Robust Impacts of Land-Use-Induced Land Cover Changes on Surface Climate over North America and Eurasia: Results from the First Set of LUCID Experiments显示文摘 | de Noblet-Ducoudré Nathalie Boisier Juan-Pablo Pitman Andy Bonan G B Brovkin V Cruz Faye Delire C Gayler V van den Hurk B J J M Lawrence P J van der Molen M K Müller C Reick C H Strengers B J Voldoire A | 2012 | EN2012，，9： | 1 |
| 19 | Extreme weather events and related disasters in the Philippines, 2004- 08: a sign of what climate change will mean?显示文摘 | Yumul G P Cruz N A Servando N T | 2011 | Disasters2011，35，2： | 1 |
| 20 | A wavelet-based image fusion tu- torial 显示文摘 | PAJARES G DE LA CRUZ J M | 2004 | Pattern Recognition2004，37，9： | 1 |
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