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| 1 | Immunological alterations in hepatitis C virus infection显示文摘A higher prevalence of immunological processes has recently been reported in patients with hepatitis C virus(HCV)infection,focusing the attention of physicians and researchers on the close association between HCV and immune disorders.HCV lymphotropism represents the most important step in the pathogenesis of virusrelated immunological diseases and experimental,virologic,and clinical evidence has demonstrated a trigger role for HCV both in systemic autoimmune diseases,such as rheumatoid arthritis,Sj?gren syndrome,hemolytic anemia and severe thrombocytopenia,and in organ-specific autoimmune diseases,such as autoimmune hepatitis,thyroid disorders and diabetes.This review will outline the principal aspects of such HCVinduced immunological alterations,focusing on the prevalence of these less characterized HCV extrahepatic manifestations. | Vincenza Calvaruso Antonio Craxì | 2013 | World Journal of Gastroenterology2013,19,47: | 11 |
| 2 | Regression of fibrosis after HBV antiviral therapy. Is cirrhosis reversible?显示文摘 | Vincenza Calvaruso Antonio Craxì | 2014 | Liver Int2014,,: | 2 |
| 3 | Extrahepatic Manifestations of Hepatitis C Virus Infection显示文摘 | Anna Linda Zignego Antonio Craxì | 2008 | Clinics in Liver Disease2008,,3: | 1 |
| 4 | Extrahepatic Manifestations of Hepatitis C Virus Infection显示文摘 | Anna Linda Zignego Antonio Craxì | 2008 | Clinics in Liver Disease2008,,3: | 1 |
| 5 | Does chemotherapy prevent HCV-related hepatocellular carcinoma? Cons显示文摘 | Antonio Craxì Calogero Cammà | 2010 | Digestive and Liver Disease2010,,: | 1 |
| 6 | Epidemiology,risk factors and surveillance of hepatocellular carcinoma显示文摘 | Cabibbo G Craxì A | | 0,,03: | 1 |
| 7 | Non-alcoholic fatty liver disease pathogenesis: The present and the future显示文摘 | S. Petta C. Muratore A. Craxì | 2009 | Digestive and Liver Disease2009,,9: | 2 |
| 8 | Is autoimmune chronic active hepatitis a HCV-related disease显示文摘 | Magrin S Craxì A Fiorentino G | | 0,,01: | 1 |
| 9 | Hepatitis C virus (HCV) infection: A systemic disease显示文摘 | Antonio Craxì Giacomo Laffi Anna Linda Zignego | 2007 | Molecular Aspects of Medicine2007,,1: | 1 |
| 10 | Non-alcoholic fatty liver disease pathogenesis:the present and the future显示文摘 | Pettaa S Muratore C Craxì A | | 0,,09: | 1 |
| 11 | Hepatitis C virus(HCV)infection:a sys temic disease显示文摘 | CraxìA Laffi G Zignego AL | 2008 | Mol Aspects Med2008,29,1: | 1 |
| 12 | The aetiology of chronic hepatitis in Italy: results from a multicentre national study显示文摘 | T. Stroffolini E. Sagnelli A. Mele A. Craxì P. Almasio | 2004 | Digestive and Liver Disease2004,,12: | 1 |
| 13 | Clinical implications of the hyperdynamic syndrome in cirrhosis显示文摘 | Anna Licata Alessandra Mazzola Daniela Ingrassia Vincenza Calvaruso Calogero Cammà Antonio Craxì | 2014 | European Journal of Internal Medicine2014,,: | 1 |
| 14 | OC-34 Clinical features and outcome of patients with drug-induced autoimmune hepatitis显示文摘 | A. Licata G. Butera F.S. Macaluso D. Cabibi A. Craxì P.L. Almasio | 2012 | Digestive and Liver Disease2012,,: | 1 |
| 15 | Hepatitis C Virus Infection Is Associated With Increased Cardiovascular Mortality: A Meta-Analysis of Observational Studies显示文摘 | Salvatore Petta Marcello Maida Fabio Salvatore Macaluso Marco Barbara Anna Licata Antonio Craxì Calogero Cammà | 2015 | Gastroenterology2015,,: | 1 |
| 16 | Seeding after radiofrequency ablation of hepatocellular carcinoma in patients with cirrhosis: A prospective study显示文摘 | F. Latteri L. Sandonato V. Di Marco P. Parisi G. Cabibbo G. Lombardo M. Galia M. Midiri M.A. Latteri A. Craxì | 2008 | Digestive and Liver Disease2008,,8: | 1 |
| 17 | Hyperuricaemia: another metabolic feature affecting the severity of chronic hepatitis because of HCV infection显示文摘 | Salvatore Petta Fabio S. Macaluso Calogero Cammà Vito D. Marco Daniela Cabibi Antonio Craxì | 2012 | Liver Int2012,,9: | 1 |
| 18 | Inguinal hernioplasty improves the quality of life in patients with cirrhosis显示文摘 | Rosalia Patti Piero Luigi Almasio Salvatore Buscemi Fausto Famà Antonio Craxì Gaetano Di Vita | 2008 | The American Journal of Surgery2008,,3: | 1 |
| 19 | clinical course and prognostic factors of hepatorenal syndrome:a retrospective single-center cohort study显示文摘AIM: To investigate clinical and biochemical features of hepatorenal syndrome(HRS), to assess short and long- term survival evaluating potential predictors of early mortality. METHODS: Sixty-two patients with liver cirrhosis and renal failure, defined as a serum creatinine value > 1.5 mg/dL on at least two measurements within 48 h, admitted to our tertiary referral Unit from 2001 to 201, were retrospectively reviewed. Among them, 33 patients(53.2%) fulfilled the revised criteria of the International Ascites Club for the diagnosis of HRS. Twenty-eight patients were treated with combinations of terlipressin and albumin, two with dopamine and al- bumin, and three with albumin alone. No patients were suitable for liver transplantation. Complete response was defined as normalization of creatinine levels to less than 1.5 mg/dL, partial response as a decrease of at least 50% but not to less than 1.5 mg/dL, no response as no reduction in creatinine or a decrease of less 50% compared to pre-treatment values. All of the patients were followed up for at least 1 year until January 2013. RESULTS: HRS type 1 was diagnosed in 15 patients(45.5%). Hepatitis C virus infection was the primary etiology(69.6%), followed by alcohol(15.2%), and cryptogenesis(15.2%). Complete response to therapy was obtained in only 3 cases(9.1%) and partial re- sponse in 7 patients(21.2%). Median survival was 30 d(range: 10-274) without significant differences be- tween type 1 and type 2 HRS. By univariate analysis, Child-Pugh class C(P = 0.009), presence of hepatocel- lular carcinoma(P = 0.04), low serum sodium(P = 0.02), high bilirubin values(P = 0.009) and high Model for End-stage Liver Disease(MELD) score(P = 0.03) were predictive factors of 30-d mortality. By multivari- ate analysis, only serum sodium < 132 mEq/L(OR = 31.39; P = 0.02) and MELD score > 27(OR = 18.72; P = 0.01) were independently associated with a survival of less than one month. CONCLUSION: HRS still has a poor prognosis, even when vasoactive drug therapies are extensively used. | Anna Licata Marcello Maida Ambra Bonaccorso Fabio Salvatore Macaluso Maria Cappello Antonio Craxì Piero Luigi Almasio | 2013 | World Journal of Hepatology2013,5,12: | 2 |
| 20 | IL28B and PNPLA3 polymorphisms affect histological liver damage in patients with non-alcoholic fatty liver disease显示文摘 | Salvatore Petta Stefania Grimaudo Calogero Cammà Daniela Cabibi Vito Di Marco Giusalba Licata Rosaria Maria Pipitone Antonio Craxì | 2012 | Journal of Hepatology2012,,6: | 2 |