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79篇 您的检索式:作者名="Coste H"
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1An integrated approach for increasing breeding efficiency in apple and peach in Europe显示文摘Despite the availability of whole genome sequences of apple and peach,there has been a considerable gap between genomics and breeding.To bridge the gap,the European Union funded the FruitBreedomics project(March 2011 to August 2015)involving 28 research institutes and private companies.Three complementary approaches were pursued:(i)tool and software development,(ii)deciphering genetic control of main horticultural traits taking into account allelic diversity and(iii)developing plant materials,tools and methodologies for breeders.Decisive breakthroughs were made including the making available of ready-to-go DNA diagnostic tests for Marker Assisted Breeding,development of new,dense SNP arrays in apple and peach,new phenotypic methods for some complex traits,software for gene/QTL discovery on breeding germplasm via Pedigree Based Analysis(PBA).This resulted in the discovery of highly predictive molecular markers for traits of horticultural interest via PBA and via Genome Wide Association Studies(GWAS)on several European genebank collections.FruitBreedomics also developed pre-breeding plant materials in which multiple sources of resistance were pyramided and software that can support breeders in their selection activities.Through FruitBreedomics,significant progresses were made in the field of apple and peach breeding,genetics,genomics and bioinformatics of which advantage will be made by breeders,germplasm curators and scientists.A major part of the data collected during the project has been stored in the FruitBreedomics database and has been made available to the public.This review covers the scientific discoveries made in this major endeavour,and perspective in the apple and peach breeding and genomics in Europe and beyond.Francois Laurens Maria JoséAranzana Pere Arus Daniele Bassi Marco Bink Joan Bonany Andrea Caprera Luca Corelli-Grappadelli Evelyne Costes Charles-Eric Durel Jehan-Baptiste Mauroux Hélène Muranty Nelson Nazzicari Thierry Pascal Andrea Patocchi Andreas Peil Bénédicte Quilot-Turion Laura Rossini Alessandra Stella Michela Troggio Riccardo Velasco Eric van de Weg 2018Horticulture Research2018,5,1:10
2Supplementing desflurane remifentanil anesthesia with small-dose ketamine reduces perioperative opioid analgegic requirements显示文摘Guignard B Coste C Costes H 2002Anesth Analg2002,95,:1
3Sites of ectopic pregnancy: a 10 year population-based study of 1800 cases显示文摘Bouyer J Coste J Fernandez H 2002Hum Reprod2002,17,12:1
4The human apolipoprotein AV gene is regulated by peroxisome proliferator-activated receptor-alpha and contains a novel farnesoid X-activated receptor response element显示文摘Prieur X Coste H Rodriguez JC 2003J Biol Chem2003,278,25:1
5Thyroid hormone regulates the hypotrigly-ceridemic gene APOA5显示文摘Prieur X Huby T Coste H 2005J Biol Chem2005,280,27:1
6Supplementing desflurane-remifentanil anesthesia with small-dose ketamine reduces perioperative opioid analgesic requirements显示文摘Guignard B Coste C Costes H 2002Anesth Analg2002,95,1:1
7Measurement of social communication skills of children with autism spectrum disorders during interactions with typical peers显示文摘Murdock L C Cost H C Tieso C 0,,03:1
8The hidden side of ectopie pregnancy: the hormonal factor显示文摘Fernandez H Bouyer J Coste J 1996Hum Reprod1996,11,2:1
9The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C显示文摘Toullec D Pianetti P Coste H 1991J Biol Chem1991,266,15:1
10Assessing foliar chlorophyll contents with the SPAD -502 chlorophyll meter: a calibration test with thirteen tree species of tropical rainforest in French Guiana显示文摘Coste S Baraloto C Leroy C Marcon Renaud A Richardson A D Roggy J C Schimann H Uddling J H6rault B 2010Annals of Forest Science2010,67,6:1
11Supplementing desflurane reminfentanil aenathesia with small-does ketamine reduces periopperative opioid analgesic requirements显示文摘Guignaxd B Coste C Costes H et aI 2002Anesth Analg2002,,95:1
12Hepatocyte nuclear factor-4α regulates the human apolipoprotein AV gene:Identification of a novel response element and involvement in the control by peroxisome proliferator-activated receptor-γ coactivator-1α,AMP-activated protein kinase,and mitogen-activated protein kinase pathway显示文摘Prieur X Schaap F G Coste H 2005Molecular Endocrinology2005,19,12:1
13Thyroid hormone regulates the hypotriglyceridemic gene APOA5 显示文摘Prieur X Huby T Coste H 2005J Bid Chem2005,280,27:1
14Role of chromosome abnormalities in ectopic pregnancy 显示文摘Coste J Fernandez H Joye N 2000Fertility and Sterility2000,74,:1
15Hepatocyte nuclear factor-4alpha regulates the human apolipoprotein AV gene:identification of a novel response element and involvement in the control by peroxisome proliferator-activated receptor-gamma coactivator-lalpha,AMP-activated protein kinase,and mitogen-activated protein kinase pathway显示文摘Prieur X Schaap FG Coste H 2005Mol Endocrinol2005,19,12:1
16Thyroid hormone regulates the hypotriglyceridemic gene ApoA5显示文摘Prieur X Huby T Coste H 2005J Biol Chem2005,280,27:1
17The human apolipoprotein AⅤ gene is regulated by peroxisome proliferator-activated receptor-alpha and contains a novel farnesoid X-activated receptor response element显示文摘Prieur X Coste H Rodriguez JC 2003J Biol Chem2003,278,25:1
18Quantivative analysis of transforming grwoth factor β1 messenger RNA in the liver of patients with chronic hepatitis C:absence of correlation between hight levels and severity of disease显示文摘Roulot D Durand H coste T 1995hepatology1995,21,:1
19The human apolipoprotein AV gene is regulated by peroxisome proliferator-activated receptor- alpha and contains a novel farnesoid X-activated receptor response element 显示文摘Prieur X Coste H Rodriguez JC 2003J Biol Chem2003,278,25:1
20Sites of ectopie pregnancy : a 10 year population - based study of 1800 cases 显示文摘Bouyer J Coste J Fernandez H 2002Hum Reprod2002,17,12:1
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