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| 1 | 活性氧化铝除氟研究显示文摘针对目前活性氧化铝饮水除氟中存在的问题,进行了生产性试验研究,通过采用原水投加CO_2气体降低pH值、小颗粒活性氧化铝、大流量短历时的NaOH循环再生法等新技术,提高了活性氧化铝的吸附容量和处理水的能力,克服滤料板结和假疲劳,除氟效果稳定可靠,水质好,再生时间短,用药省,降低了基建投资和运转费用。 | North China Municipal Engineering Design Institute A full-scale plant was set up for studying the existing problems on the fluoride removal from drinking water by activated alumina. Some new methods was adopted,such as the addition of CO2to reduce water pH value,the use of small-sized activated alumina,and the employment of a cyclic regeneration at large flow rate with NaOH as regenerant,which result in the improvement of adsorption capacity of activated alumina and treatment capacity, the elimination of the hardening of filtration materials and false fatigue,stable and reliable effectiveness,good quality in water,short regeneration time,small consumption of regenerant. And then the capital and openational costs were reduced. | 1989 | 中国给水排水1989，5，3： | 5 |
| 2 | Tumor cells educate mesenchymal stromal cells to release chemoprotective and immunomodulatory factors显示文摘Factors released by surrounding cells such as cancer-associated mesenchymal stromal cells(CA-MSCs)are involved in tumor progression and chemoresistance.In this study,we characterize the mechanisms by which naYve mesenchymal stromal cells(MSCs)can acquire a CA-MSCs phenotype.Ovarian tumor cells trigger the transformation of MSCs to CA-MSCs by expressing pro-tumoral genes implicated in the chemoresistance of cancer cells,resulting in the secretion of high levels of CXC chemokine receptors 1 and 2(CXCR1/2)ligands such as chemokine(C-X-C motif)ligand 1(CXCL1),CXCL2,and interleukin 8(IL-8).CXCR1/2 ligands can also inhibit the immune response against ovarian tumor cells.Indeed,through their released factors,CA-MSCs promote the differentiation of monocytes towards M2 macrophages,which favors tumor progression.When CXCR1/2 receptors are inhibited,these CA-MSC-activated macrophages lose their M2 properties and acquire an anti-tumoral phenotype.Both ex vivo and in vivo,we used a CXCR1/2 inhibitor to sensitize ovarian tumor cells to carboplatin and circumvent the pro-tumoral effects of CA-MSCs.Since high concentrations of CXCR1/2 ligands in patients*blood are associated with chemoresistance,CXCR1/2 inhibition could be a potential therapeutic strategy to revert carboplatin resistance. | Augustin Le Naour Melissa Prat Benolt Thibault Renaud Mével Léa Lemaitre Helene Leray Marie-Veronique Joubert Kimberley Coulson Muriel Golzio Lise Lefevre Eliane Mery Alejandra Martinez Gwénael Ferron Jean-Pierre Delord Agnès Coste Bettina Couderc | 2020 | Journal of Molecular Cell Biology2020，12，3： | 3 |
| 3 | Nasal immunization with Salmonella typhimurium producing Rotavirus VP2 and VP6 antigens stimulates specific antibody response in serum and milk but fails to protect offspring显示文摘 | Cohen J Reinhardt M | 2001 | Vaccine2001，19，30： | 1 |
| 4 | The prognosis of heart failure in the general population:The rotterdam study显示文摘 | Cost B Hoes AW | 2001 | Eur Heart J2001，22，： | 1 |
| 5 | Multiple immuno-regulatory defects in type-1 diabetes 显示文摘 | Kukreja A Cost G Marker J | 2002 | J Clin Invest2002，109，1： | 1 |
| 6 | Unique high- temperature facility for studying organic reactions in the Ba- yer process显示文摘 | COSTING A LOH J MCDONALD R | 2010 | Light Metals2010，，2： | 1 |
| 7 | A mutation in Taclp, a transeription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans显示文摘 | Coste A Turner V Ischer F | 2006 | Genetics2006，172，4： | 1 |
| 8 | Incomplete resolution of ST-segment elevation is a marker of transient microcirculatory dysfunction after stenting for acute myocardial infarction显示文摘 | Feldman LJ Coste P Furber A | 2003 | Circulation2003，107，： | 1 |
| 9 | Genotypic evolu-tion of azole resistance mechanisms in sequential Candidaalbicans isolates显示文摘 | Coste A Selmeeki A Forehe A | 2007 | Eukaryot Cell2007，6，10： | 1 |
| 10 | Both soluble and membrane-anchored forms of felid herpesvirus 1 glycoprotein G function as a broad-spectrum chemokinebinding protein显示文摘 | COSTES B RUIZ-ARGUELLO M B BRYANT N A | 2005 | J Gen Virol2005，86，12： | 1 |
| 11 | The prognosis of heart failure in the generalk population:The Rotterdam Study显示文摘 | Mosterd A Cost B Hoes AW | 2001 | Eur Heart J2001，22，15： | 1 |
| 12 | Incomplete resolution of ST-segment elevation is a marker of transient microcirculatory dysfunction after stenting for acute myocardial infarction显示文摘 | FELDMAN LJ COSTE P FURBER A | 2003 | Circulation2003，107，21： | 1 |
| 13 | Pharmacological charac-terization of muscarinic receptors implicated in rabbit detru-sor muscle contraction and activation of inositol phospholip-ids hydrolysis in rabbit detrusor and parotid gland显示文摘 | Barros M Coste A Eon MT | 1999 | Fun-dam Clin Pharmacol1999，13，5： | 1 |
| 14 | The hepatitis B virus X protein abrogates Bcl-2-mediated protection against Fas apoptosis in the liver显示文摘 | Terradillos O de La Coste A Pollicino T | 2002 | Oncogene2002，21，： | 1 |
| 15 | Stability of carmustine in polyvinyl chloride bags and polyethylene-lined trilayer plastic containers显示文摘 | Favier M De Cazanove F Coste A | 2001 | Am J Health Syst Pharm2001，58，3： | 1 |
| 16 | Multiple immuno-regulatory defects in type-1 diabetes显示文摘 | Kukreja A Cost G Marker J | 2002 | J Clin Invest2002，109，1： | 1 |
| 17 | Effects of neutron irradiation on Nd-Fe-B magnetic properties显示文摘 | J R COST R D BROWN A L GIORGI | 1988 | IEEE Trans Mag1988，24，3： | 1 |
| 18 | Functional endoscopic sinus surgery for isolated sphenoid sinus diseases显示文摘 | GILAIN L AIDAN D COSTE A | 1994 | Head Neck1994，16，： | 1 |
| 19 | Chemotherapy of advanced small- bowel adenocarcinoma:a multicenter AGEO study显示文摘 | Zaanan A Costes L Gauthier M | 2010 | Ann Oncol2010，21，9： | 1 |
| 20 | Plant regrowth from potatoshoot tips cryopreserved by a combined vitrification dropletmethod显示文摘 | Halmagyi A Deliu C Coste A | 2005 | CryoLetters2005，26，： | 1 |
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