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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Interaction of lithium with graphene: an ab initio study 显示文摘 | KHANTHA M CORDERO N A MOLINA L M | 2004 | Physical Review B2004，70，12： | 1 |
| 3 | Surface changes of alumina induced by phosphoric acid impregnation 显示文摘 | Cordero R L | 1989 | Applied Catalysis1989，56，： | 1 |
| 4 | Genetic variation in the interleukin-8 gene promoter and vaginal concentrations of interleukin--8 are not associated with bacterial vaginosis during pregnancy显示文摘 | Diaz-Cueto L Cuiea Flores A Ziga Cordero F | 2005 | J Reprod Immuno12005，66，2： | 1 |
| 5 | The Actin cross-linking domain of the Vibrio cholerae RTX toxin directly catalyzes the covalent cross-linking of actin显示文摘 | Christina L Cordero Dmitry S | 2006 | Biological Chemistry2006，281，32： | 1 |
| 6 | A comparison of two airway suctioning frequencies in mechanically ventilated,very-low-birthweight infants显示文摘 | Cordero L Sananes M Ayers LW | 2001 | Respir Care2001，46，： | 1 |
| 7 | Effect of confinement on the deformation of microfluidic drops 显示文摘 | Ulloa C Ahumada A Cordero M L | 2014 | Physical Review E2014，89，： | 1 |
| 8 | Gingivitis de c61ulas plasm6ti- cas:Reporte de caso y revisi6n de literatura 显示文摘 | Ulloa P L Cordero 0 R Bolafios D C | 2006 | Odovtos2006，8，： | 1 |
| 9 | Comparisen of a closed (trach care ) vs an open endotracheal suction system in newborns显示文摘 | Cordero L Sananes M Ayers L et aI | 1999 | Pediatric Research1999，45，4： | 1 |
| 10 | Cloud point preconcentration and high-performance liquid chromatographic determination of organophosphorus pesticides with dual electrochemical detection 显示文摘 | PINTO C G PEREZ J L CORDERO B M | 1995 | Anal Chem1995，67，： | 1 |
| 11 | Comparison of a closed(Trach Care MAC) with an open endotracheal suction system in small premature infants显示文摘 | Cordero L Sananes M Ayers L | 2000 | J Perinatol2000，20，3： | 1 |
| 12 | Purulence and gramnegative bacilli in tracheal aspirates of mechanically ventilated very low birth weight infants 显示文摘 | Cordero L Sananes M Dedhiya P | 2001 | J Perinatol2001，21，6： | 1 |
| 13 | How the measurementsof a few serum markers can be combined to enhancetheir clinical values in the management of cancer 显示文摘 | Cordero OJ De Chiara L Lemos-Gonzalez Y | 2008 | AnticancerRes2008，28，4： | 1 |
| 14 | Analytical applications of membrane extraction in chromatography and electrophoresis显示文摘 | Cordero B M Pavon J L P Pinto C G | 2000 | Journal of Chromatography A2000，902，1： | 1 |
| 15 | Continuing education and community pharmacists in Gali- cia: a study of Opinions 显示文摘 | Cordero L Cadavid MI Fem6ndez- Llim6s F | 2004 | Pharm World Sci2004，26，3： | 1 |
| 16 | Micellemediated methodologu for the preeoneentration of uranion prior to its determination by flow-injection 显示文摘 | Laespada M E F Pavon J L P Cordero B M | 1993 | Analyst1993，118，： | 1 |
| 17 | Interleukin-2 killer cells:in vitro evaluation of combination with prothymosin alpha显示文摘 | LOPEZ-RODRIGUEZ J L CORDERO O J SARANDESES C | 1994 | Lymphokine Cytokine Res1994，13，3： | 1 |
| 18 | On the oxidation resistance of carbon-carbon composites obtained by chemical vapor infiltration of different carbon cloths显示文摘 | Thrower P A Radovic L R | 1992 | Carbon1992，30，： | 1 |
| 19 | A comparison of two airway suctioning frequencies in mechanically ventilated, very- low - birthweight infants显示文摘 | Cordero L Sananes M Ayers LW | 2001 | Respir Care2001，46，： | 1 |
| 20 | Genetic and bioclimatic variation in Solanum pimpinellifolium显示文摘 | Zuriaga E Blanca J M Cordero L Sifres A Blas-Cerdán W G Morales R Nuez F | | 0，，： | 1 |
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