|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Combined carriership of TLR9 -1237C and CD14 -260T alleles enhances the risk of developing chronic relapsing pouchitis显示文摘AIM: To investigate the single nucleotide polymorphisms (SNPs) in genes involved in bacterial recognition and the susceptibility to pouchitis or pouchitis severity.METHODS: Analyses of CD14 -260C>T, CARD15/NOD2 3020insC, Toll-like receptor (TLR)4 +896A>G,TLR9 -1237T>C, TLR9+ 2848G>A, and IRAKM +22148G>A SNPs were performed in 157 ileal-pouch anal anastomosis (IPAA) patients (79 patients who did not develop pouchitis, 43 infrequent pouchitis patients,35 chronic relapsing pouchitis patients) and 224 Italian Caucasian healthy controls.RESULTS: No significant differences were found in SNP frequencies between controls and IPAA patients.However, a significant difference in carriership frequency of the TLR9-1237C allele was found between the infrequent pouchitis and chronic relapsing pouchitis groups [P = 0.028, odd's ratio (OR) = 3.2, 95%CI = 1.2-8.6].This allele uniquely represented a 4-locus TLR9 haplotype comprising both studied TLR9 SNPs in Caucasians.Carrier trait analysis revealed an enhanced combined carriership of the alleles TLR9 -1237C and CD14 -260T in the chronic relapsing pouchitis and infrequent pouchitis group (P = 0.018, OR = 4.1, 95%CI = 1.4 -12.3).CONCLUSION: There is no evidence that the SNPs predispose to the need for IPAA surgery. The significant increase of the combined carriership of the CD14 -260T and TLR9 -1237C alleles in the chronic relapsing pouchitis group suggests that these markers identify a subgroup of IPAA patients with a risk of developing chronic or refractory pouchitis. | KM Lammers S Ouburg SA Morré JBA Crusius P Gionchetti F Rizzello C Morselli E Caramelli R Conte G Poggioli M Campieri AS Pea | 2005 | World Journal of Gastroenterology2005，11，46： | 7 |
| 2 | Pediatric endocrinology update : an overview 显示文摘 | Mac Gillivray MH Morishima A Conte F | 1998 | Horm Res1998，49，1： | 1 |
| 3 | Severe coronary artery disease after radiation therapy of the chest and mediastinum: clinical presentation and treatment 显示文摘 | ORZAN F BRUSCA A CONTE M R | 1993 | Br Heart J1993，69，6： | 1 |
| 4 | Stability analysis of slopes in soils with strain-softening behavior显示文摘 | Conte E Silvestri F Troncone A | 2010 | Computers and Geotechnics2010，37，5： | 1 |
| 5 | Economic Growth and the Expanding Public Sector: A Reexamination显示文摘 | Conte M A A F Darrar | 1988 | The Review of Economics and Statistics1988，70，2： | 1 |
| 6 | Phosphorylation of the TGBpl movement protein of Potato virus X by a Nicotiana tabacum CK2-like activity显示文摘 | Modena N A Zelada A M Conte F | 2008 | Virus Res2008，137，1： | 1 |
| 7 | Hydrochlorination of acetylene using supported bimetallic Au-based catalysts显示文摘 | Conte M Carley A F Attard G | 2008 | Journal of Catalysis2008，257，： | 1 |
| 8 | Hydrochlorination of acetylene using a supported gold catalyst: A study of the reaction mechanism显示文摘 | Conte M Carley A F Heirene C | 2007 | Journal of Catalysis2007，250，2： | 1 |
| 9 | Reactivation of a carbonsupported gold catalyst for the hydrochlorination of acetylene显示文摘 | Conte M Carley A F Hutchings G J | 2008 | Catalysis Letters2008，124，34： | 1 |
| 10 | Congenital hypogonadotropic hypogonadism and micropenis:effect of testosterone treatment on adult penile size why sex reversal is not indi-cated显示文摘 | BIN ABBAS B CONTE F A GRUMBACH MM | 1999 | J Pediatr1999，134，5： | 1 |
| 11 | Surgical management of neonatal coarctation显示文摘 | CONTE S LACOUR-GAYET F SERRAF A | 1995 | J Thorac Cardiovasc Surg1995，109，： | 1 |
| 12 | Clinical, genetic and functional characterization of adrenocorticotropin receptor mutations using a novel receptor assay显示文摘 | Fluck C E Martens J W Conte F A | 2002 | J Clin Endocrinol Metab2002，87，9： | 1 |
| 13 | The molec ular characterization of a novel GH38 alpha-mannosidase from the crenarchaeon Sulfolobus solfataricus revealed its ability in de-mannosylating glycoproteins显示文摘 | Cobueci-Ponzano B Conte F Strazzulli A | 2010 | Biochimie2010，92，12： | 1 |
| 14 | Practical and theoretical implication of fetal/maternal lymphocyte transfer显示文摘 | Walknowska J Conte F A Grumbach M M | 1969 | Lancet1969，1，7606： | 1 |
| 15 | Hydrochlorination of acetylene using a supported gold catalyst: a study of the reaction mechanism 显示文摘 | Conte M Carley A F Heirene C | 2007 | Journal of Catalysis2007，250，2： | 1 |
| 16 | Efficacy of paracetamol for the treatment of patent ductus arteriosus in preterm neonates 显示文摘 | Terrin G Conte F Scipione A | 2014 | Ital J Pediatr2014，40，1： | 1 |
| 17 | Types of kidney calculi relationship with urinary biochemistry显示文摘 | Grases Freixedas F Conte Visus A Costa Bauza A | 2001 | Arch Esp Urol2001，54，9： | 1 |
| 18 | Practical and Theoretical Implications of Fetal-maternal Lymphocyte Transfer显示文摘 | Walknowska J Conte F A Grumbach M M | 1969 | Lancet1969，1，： | 1 |
| 19 | Modeling Bus Contention and Memory Interference in a Multiprocessor System 显示文摘 | M A Marsan G Balbo G Conte and F Gregoretti | 1983 | IEEE Bans on Computers1983，032，01： | 1 |
| 20 | Reactivation of a carbon-supported gold catalyst for the hydrochlorination of acetylene显示文摘 | Conte M Carley A F Hutchings G J | 2008 | Catalysis Letters2008，124，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员