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| 1 | Comparison of visual acuity outcomes between ranibizumab and bevacizumab treatment in neovascular age-related macular degeneration显示文摘AIM:To compare visual acuity(VA) outcomes between intravitreal injection of bevacizumab and ranibizumab in the treatment of neovascular age-related macular degeneration(AMD).· METHODS:We conducted a consecutive,retrospective case series study in patients with newly diagnosed all type choroidal neovascularization(CNV) secondary to AMD who received an intravitreal injection of bevacizumab(1.25mg) or ranibizumab(0.3mg) at Lions Eye Institute,Western Australia from Mar.2006 to May 2008.All patients received injection at baseline with additional monthly injections given at the discretion of the treating physician.Main outcome measures were changes in VA.· RESULTS:There were 371 consecutive patients received injection at least in one eye with at least 6 months of follow up(median of 12.0 months).Bevacizumab treatment prevented 221 out of 278(79.5%) patients from losing <15 letters in VA compared with 79 out of 93(84.9%) of ranibizumab treated patients(P=0.25).While 68(24.5%) of bevacizumab treated patients gained ≥15 letters of VA compared with 24(25.8%) of ranibizumab treated patients(P=0.79).75.3% and 66.2% patients benefited from ranibizumab and bevacizumab respectively with final VA better than 6/60(P=0.10).Multivariate analysis showed that pre-treatment VA was negatively associated with benefit outcome.Assignment of injection was not associated with VA outcome of benefit after adjusting the covariate(P=0.857).CONCLUSION:There are no difference in treatment efficacy in terms of VA between bevacizumab and ranibizumab in routine clinical condition. | Ian J Constable Ian L McAllister Timothy Isaacs | 2011 | International Journal of Ophthalmology(English edition)2011，4，1： | 3 |
| 2 | Continuous electrical resistance monitoring,pull strength,and fatigue life of isotropically conductive adhesive joints显示文摘 | Constable J H Kache T Teichmann H | | 0，，： | 1 |
| 3 | An introduction to marinecontrolled source electromagnetic methods for hydro-carbonexploration 显示文摘 | CONSTABLE S SRNKA L J | 2007 | Geophysics2007，72，2： | 1 |
| 4 | The coordination chemistry of 4'-phenyl-2,2':6',2″-terpyridine;the synthesis,crystal and molecular structures of 4'-phenyl-2,2':6',2″-terpyridine and bis(4'-phenyl-2,2':6',2″-terpyridine)nickel(11)chloride decahydrate显示文摘 | Constable E C Lewis J Liptrot M C | 1990 | Inorganic Chimica Acta1990，178，1： | 1 |
| 5 | Key green chemistry research areas-A perspective from pharmaceutical manufacturers 显示文摘 | Constable D J C Dunn P J Hayler J D | 2007 | Green Chem2007，9，： | 1 |
| 6 | Antimetabolites-induced apoptosis in Tenon' s capsule fibroblasts 显示文摘 | Crowston J G Akbar A N Constable P H | 1998 | Invest Ophthalmol Vis Scl1998，39，6： | 1 |
| 7 | Temporal and light-based changes in carbon uptake and storage in the spring ephemeral Podophyllum peltatum (Berberidaceae) 显示文摘 | Constable J V H Peffer B J De Nicola D M | 2007 | Environmental and Experimental Botany2007，60，1： | 1 |
| 8 | Whole-body deletion of LPS-induced TNF-alpha factor (LITAF) markedly improves experimental endotoxic shock and inflammatory arthritis 显示文摘 | You J Constable C | 2011 | ProcNatlAcadSciUSA2011，108，21： | 1 |
| 9 | Defining smaller-scale management units to further develop the ecosystem approach in managing large-scale pelagic krill fisheries in Antarctica 显示文摘 | CONSTABLE A J NICOL S | 2002 | CCAMLR Science2002，，9： | 1 |
| 10 | Mapping thin resistors and hydro- carbons with marine EM methods : Insights from 1D mod- eling显示文摘 | Constable S Weiss C J | 2006 | Geophysics2006，71，2： | 1 |
| 11 | Activation of glucose transport in muscle by exercise显示文摘 | Holloszy J O Constable SH Young DA | 1986 | Diabetes Metab Rev1986，1，4： | 1 |
| 12 | The effect of social support and the work environment upon burnout among nurses显示文摘 | CONSTABLE J F RUSSELL D W | 1986 | J Human Stress1986，12，1： | 1 |
| 13 | An introduction to marine controlled source electromagnetic methods for hydrocarbon exploration 显示文摘 | CONSTABLE S SRNKA L J | 2007 | Geophysics2007，72，2： | 1 |
| 14 | Measurement of the point spread function in MRI using constant time imaging显示文摘 | Robson M D Gore J C Constable R T | 1997 | Magn Reson Med1997，38，5： | 1 |
| 15 | Nuclear DNA from Primate Dung 显示文摘 | CONSTABLE J J PACKER C COLLINS D A | 1995 | Nature1995，373，： | 1 |
| 16 | An Introduction to Marine Controlled Source Electromagentic Methods for Hydrocarbon Exploration显示文摘 | Constable S Srnka L J | 2007 | Geophysics2007，72，2： | 1 |
| 17 | Temporal and light-based changes in carbon uptake and storage in the spring ephemeral Podophyllum peltatum (Berberidaceae)显示文摘 | Constable J V H Peffer B J DeNicola D M | 2007 | Environmental and Experimental Botany2007，60，1： | 1 |
| 18 | Estimation of the N fertilizer requirement of cotton grown aider legume crops显示文摘 | Rochhe:ter I J Peoples M B Constable G A | 2001 | Field Crop research2001，，70： | 1 |
| 19 | Demonstration of a fiber-optical light-force trap显示文摘 | CONSTABLE A KIM J MERVIS J | 1993 | Optics Letters1993，18，： | 1 |
| 20 | Proofs as programs显示文摘 | Bates J L Constable R L | 1985 | Communications of the ACM 71985，1985，： | 1 |
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