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1篇 您的检索式：作者名="Colleen A.Barrick"

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		题名	作者	年代	出处	被引量
	1	Sexually Dimorphic BDNF Signaling Directs Sensorylnnervation of the Mammary Gland显示文摘How neural circuits associated with sexually dimorphic organs are differentially assembledduring development is unclear.Here,w e report a sexually dimorphic pattern of mouse mammary glandsensory innervation and the mechanism of its formation.Brain-derived neurotrophic factor(BDNF),emanating from mammary mesenchyme and signaling through its receptor TrkB on sensory axons,isrequired for establishing mammary gland sensory innervation of both sexes at early edvelopmentalstages.Subsequently,in males,androgens promote mammary mesenchymal expression of a truncatedform of TrkB,w hich prevents BDNF-TrkB signaling in sensory axons and leads to a rapid loss ofmammary gland innervation independent of neuronal apoptosis.Thus,sex hormone regulation of aneurotrophic factor signal directs sexually dimorphic axonal grow th and maintenance,resulting ingeneration of a sex-specific neural circuit.	Yin Liu Michael Rutlin Siyi Huang Colleen A.Barrick Fan Wang Kevin R.Jones Lino Tessarollo David D.G inty	2013	同济大学学报(医学版)2013，34，3：	0

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