|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma显示文摘This study investigates aberrant DNA methylations as potential diagnosis and prognosis markers for esophageal squamous-cell carcinoma(ESCC),which if diagnosed at advanced stages has<30%five-year survival rate.Comparing genome-wide methylation sites of 91 ESCC and matched adjacent normal tissues,we identified 35,577 differentially methylated CpG sites(DMCs)and characterized their distribution patterns. | Yiyi Xi Yuan Lin Wenjia Guo Xinyu Wang Hengqiang Zhao Chuanwang Miao Weiling Liu Yachen Liu Tianyuan Liu Yingying Luo Wenyi Fan Ai Lin Yamei Chen Yanxia Sun Yulin Ma Xiangjie Niu Ce Zhong Wen Tan Meng Zhou Jianzhong Su Chen Wu Dongxin Lin | 2022 | Signal Transduction and Targeted Therapy2022，7，3： | 2 |
| 2 | Evaluating carbon dioxide emissions in international trade of China显示文摘 | Boqiang Lin Chuanwang Sun | 2009 | Energy Policy2009，，1： | 2 |
| 3 | Evaluating carbon dioxide emissions in international trade of China显示文摘 | LIN Boqiang SUN Chuanwang | 2010 | Energy Policy2010，38，： | 1 |
| 4 | Overexpression of carboxylesterase gene associated with organophosphorus insecticide resistance in cotton aphids,Aphis gossypii(Glover)显示文摘 | Cao Chuanwang Zhang Jing Gao Xiwu | 2008 | Pestic Biochem Physiol2008，90，3： | 1 |
| 5 | Evaluating carbon dioxide emissions in international trade of China显示文摘 | Boqiang Lin Chuanwang Sun | | 0，，01： | 1 |
| 6 | Evaluating Carbon Dioxide Emissions in International Trade of China显示文摘 | Lin Boqiang and Chuanwang Sun 2010 | 2010 | Energy Policy2010，，38： | 1 |
| 7 | Increased expression of calcium‐sensing receptors induced by ox‐LDL amplifies apoptosis of cardiomyocytes during simulated ischaemia–reperfusion显示文摘 | JinGuo Hong‐ZhuLi Wei‐HuaZhang Lu‐ChuanWang Li‐NaWang LiZhang Guang‐WeiLi Hong‐XiaLi Bao‐FengYang LingyunWu RuiWang Chang‐QingXu | 2010 | Clinical and Experimental Pharmacology and Physiology2010，，3： | 1 |
| 8 | VAV2 is required for DNA repair and implicated in cancer radiotherapy resistance显示文摘Radiotherapy remains the mainstay for treatment of various types of human cancer;however,the clinical efficacy is often limited by radioresistance,in which the underlying mechanism is largely unknown.Here,using esophageal squamous cell carcinoma(ESCC)as a model,we demonstrate that guanine nucleotide exchange factor 2(VAV2),which is overexpressed in most human cancers,plays an important role in primary and secondary radioresistance.We have discovered for the first time that VAV2 is required for the Ku70/Ku80 complex formation and participates in non-homologous end joining repair of DNA damages caused by ionizing radiation. | Weiling Liu Chuanwang Miao Shaosen Zhang Yachen Liu Xiangjie Niu Yiyi Xi Wenjia Guo Jiahui Chu Ai Lin Hongjin Liu Xinyu Yang Xinjie Chen Ce Zhong Yuling Ma Yuqian Wang Shihao Zhu Shuning Liu Wen Tan Dongxin Lin Chen Wu | 2021 | Signal Transduction and Targeted Therapy2021，6，9： | 1 |
| 9 | Ripple+:An Improved Scheme of Ripple Consensus Protocol in Deployability,Liveness and Timing Assumption显示文摘Ripple acts as a real-time settlement and payment system to connect banks and payment providers.As the consensus support of the Ripple network to ensure network consistency,Ripple consensus protocol has been widely concerned in recent years.Compared with those Byzantine fault tolerant protocols,Ripple has a significant difference that the system can reach an agreement under decentralized trust model.However,Ripple has many problems both in theory and practice,which arementioned in the previous researches.This paper presents Ripple+,an improved scheme of Ripple consensus protocol,which improves Ripple fromthree aspects:(1)Ripple+employs a specific trustmodel and a corresponding guideline for Unique Node List selection,which makes it easy to deploy in practice to meet the safety and liveness condition;(2)the primary and viewchangemechanismare joined to solve the problem discussed by the previous research that Ripple may lose liveness in some extreme scenarios;(3)we remove the strong synchrony clock and timeout during consensus periods to make it suitable for weak synchrony assumption.We implemented a prototype of Ripple+and conducted experiments to show that Ripple+can achieve the throughput of tens of thousands of transactions per second with no more than half a minute latency,and the view change mechanism hardly incurs additional cost. | Chuanwang Ma Yu Zhang Binxing Fang Hongli Zhang Yidong Jin Dasheng Zhou | 2022 | Computer Modeling in Engineering & Sciences2022，，1： | 1 |
| 10 | Evaluating the Public Perceptions of Nuclear Power in China:Evidence from a Contingent Valuation Survey显示文摘 | Chuanwang Sun Xiting Zhu | 2014 | Energy Policy2014，，6： | 1 |
| 11 | Increased expression of calcium‐sensing receptors induced by ox‐LDL amplifies apoptosis of cardiomyocytes during simulated ischaemia–reperfusion显示文摘 | JinGuo Hong‐ZhuLi Wei‐HuaZhang Lu‐ChuanWang Li‐NaWang LiZhang Guang‐WeiLi Hong‐XiaLi Bao‐FengYang LingyunWu RuiWang Chang‐QingXu | 2010 | Clinical and Experimental Pharmacology and Physiology2010，，3： | 1 |
| 12 | Evaluating carbon dioxide emissions in international trade of China 显示文摘 | Boqiang Lin Chuanwang Sun | 2010 | En- ergy Policy2010，，： | 1 |
| 13 | Evaluating carbon dioxide emis- sions in international trade of China显示文摘 | Lin Boqiang Sun Chuanwang | 2010 | Energy Policy2010，38，1： | 1 |
| 14 | Overexpression of carboxylesterase gene associated with organophosphorous insecti- cide resistance in cotton aphids, Aphis gossypii (Glover) 显示文摘 | Cao Chuanwang Zhang Jing Gao Xiwu | 2008 | Pesticide Biochemistry and Physiology2008，90，： | 1 |
| 15 | Evaluating carbon dioxide emissions in international trade of China显示文摘 | Boqiang Lin Chuanwang Sun | 2009 | Energy Policy2009，，1： | 1 |
| 16 | Evaluating carbon dioxide emissions in international trade of China 显示文摘 | Boqiang Lin Chuanwang Sun | 2010 | Energy Policy2010，，38： | 1 |
| 17 | Low dispersion broadband integrated double-slot microring resonators optical buffer显示文摘 | ChuanWANG Xiaoying LIU Minming ZRANG Peng ZHOU | 2016 | Frontiers of Optoelectronics2016，9，4： | 0 |
| 18 | Temporal Characteristics of the Queueing Process ot 3uffer-aided Wireless Communications显示文摘 | DONG Yunquan FAN Pingyi LI Enyu SONG Chuanwang LI Yansheng | 2014 | China Communications2014，11，A01： | 0 |
| 19 | Effect of Spinosad on Detoxifying and Protective Enzymes of Malacosoma neustria testacea显示文摘To study the insecticidal activity and toxicity mechanism of spinosad,we assayed bioactivity of spinosad by leaf membrane method and its effects on the activities of detoxifying and protective enzymes in Malacosoma neustria testacea larvae by spectrophotometry.The results showed that spinosad had an extremely high toxicity against the 4th and 5th instar larvae.The glutathione S-transfer (GST) activity in 4th and 5th instar larvae was firstly inhibited,then induced,and finally inhibited,while the mixed-functional oxidase(MFO) activity was inhibited and then enhanced.The induced effect on carboxylesterase(CarE),the induced and inhibited effect on acetylcholinesterase (AchE) and peroxidase(POD),and the complicated effects on superoxide dismutase(SOD) and Catalase(CAT) were determined in 4th instar larvae with spinosad treatment.However,the obvious inhibition effects were found on the activities of CarE,AchE,SOD and POD in the 5th instar larvae whereas the catalase(CAT) activity was inhibited, then increased,and inhibited finally.Therefore, spinosad could effectively disrupt and interfere not only the detoxifying and protective enzymes but also normal physiological metabolism of M.neustria testacea and show extremely high toxicity against this pest. | Liu Dan Yan Shanchun Cao Chuanwang Liao Yuezhi | 2012 | Chinese Forestry Science and Technology2012，11，3： | 0 |
| 20 | A cis-eQTL in NSUN2 promotes esophageal squamous-cell carcinoma progression and radiochemotherapy resistance by mRNA-m^(5)C methylation显示文摘Dear Editor,Esophageal squamous cell carcinoma(ESCC)has poor prognosis because of the difficulty in early detection and low sensitivity of advanced disease to radiochemotherapy.1,2 ESCC presents a high proportion of primary resistance to radiochemotherapy,2which may be due to certain individual genetic variations.Expression quantitative trait loci(eQTLs)as proximal and continuous cellular phenotypes have been shown to be helpful to determine how genetic variants may influence phenotype. | Xiangjie Niu Linna Peng Weiling Liu Chuanwang Miao Xinjie Chen Jiahui Chu Xinyu Yang Wen Tan Chen Wu Dongxin Lin | 2022 | Signal Transduction and Targeted Therapy2022，7，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员