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| 1 | High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate. | Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo | 2013 | World Journal of Gastroenterology2013，19，20： | 23 |
| 2 | Review on Recent Developments of Fluorescent Oxygen and Carbon Dioxide Optical Fiber Sensors显示文摘氧和二氧化碳传感器涉及许多化学、生物化学的反应。因而,在年的可观的努力被奉献了为由光纤维传感器测量煤气的集中发现并且改善合适的技术。光煤气的传感器由与高渗透在一个矩阵骗诱到气体的气体敏感的染料组成。与如此的传感器,煤气的集中被评估在射出的状态熄灭的气体引起的光紧张在减小之上基于。然而,熄灭氧的效果的光对温度高度敏感。因此,为温度和氧的双察觉到的一个简单、便宜塑料光纤维传感器被介绍。另外,当温度被上面的双传感器获得时,一个修改 Stern-Volmer 模型被介绍补偿温度飘移。最近,我们介绍了高度敏感的氧并且溶解了与 meso-tetrakis (pentafluorophenyl ) 卟啉(PtTFPP ) 和 PtTFPP 骗诱的铂(II ) 包括在一结束涂的光纤维的氧传感器在 n-octyltriethoxysilane (Octyl-triEOS ) 嵌入的核心壳硅石 nanoparticles /tetraethylorthosilane (TEOS ) 合成 xerogel。另外,为在非同类的样品的化学参数的分发的二维的煤气的测量被开发并且具有对医药、生物的研究的兴趣。 | Cheng-Shane CHU Yu-Lung LO Ti-Wen SUNG | 2011 | Photonic Sensors2011，1，3： | 7 |
| 3 | 高功率等离子磁控溅射法制备含钛类金刚石碳膜(英文)显示文摘为了改善类金刚石碳膜的性能,采用高功率等离子磁控溅射法将含钛非晶碳薄膜沉积在304不锈钢基材上,气源为C2H2-Ar混合气体,金属钛为阴极靶材。为了改善附着力和降低残余应力,制备了含Ti/TiC/DLC多层结构的镀膜。利用GDS、XRD、SEM、Raman光谱法、纳米压痕仪和盘-销摩擦计研究基材偏压及基材与靶材的距离对薄膜性能的影响。结果表明,薄膜具有优良的粘合强度和韧性。 | YANG Peng SUNG Chia-chi FUH Yiin-Kuen CHU Chun-lin LO Chih-hung | 2012 | Transactions of Nonferrous Metals Society of China2012，22，6： | 4 |
| 4 | Single atom and defect engineering of CuO for efficient electrochemical reduction of CO_(2) to C_(2)H_(4)显示文摘Electrochemical CO_(2) transformation to high‐value ethylene(C_(2)H_(4))at high currents and efficiencies is desired and yet remains a grand challenge.We show for the first time that coupling single Sb atoms and oxygen vacancies of CuO enable synergistic electrocatalytic reduction of CO_(2) to C_(2)H_(4) at low overpotentials.Highly dispersed Sb atoms occupying metal substitutional sites of CuO are synthesized under mild conditions.The overall CO_(2) reduction faradaic efficiency(FE)reaches 89.3±1.1%with an FE toward C_(2)H_(4) exceeding 58.4%at a high‐current density of 500 mA/cm^(2).Addition of the p‐block metal is found to induce transformation of CuO from flakes to nanoribbons rich in nanoholes and oxygen vacancies,greatly enhancing CO_(2) adsorption and activation while suppressing hydrogen evolution.Further density functional theory calculations with in situ X‐ray diffraction reveal that combining Sb sites and oxygen vacancies prominently lessen the dimerization energy of adsorbed CO intermediate,thus boosting the conversion of CO_(2) to produce C_(2)H_(4).This study provides a new perspective for promoting selective C-C coupling for electrochemical CO_(2) reduction. | Senlin Chu Changwoo Kang Woonghyeon Park Yu Han Song Hong Leiduan Hao Hao Zhang Tsz Woon Benedict Lo Alex W.Robertson Yousung Jung Buxing Han Zhenyu Sun | 2022 | SmartMat2022，3，1： | 3 |
| 5 | Echocardiographic mapping of left ventricular resynchronization during cardiac resynchronization therapy procedures显示文摘背景心脏的再同步治疗(CRT ) 是为病人与的有效电的治疗对严重的心失败和心脏的 dyssynchrony 中等。这研究试图调查度尖锐留给室( LV )在不同 LV 地点并且到的有 biventricular 踱步的再同步( BVP )检验执行 transthoracic echocardiography ( TTE )确定的可行性尖锐 LV 再同步在 CRT procedure.Methods 期间有 NYHA 班的十四个病人心失败, LV 喷射部分35%, QRS 持续时间 120 ms 和氏族侧面的延期( SLD )织物 Doppler 成像( TDI )上的 60 ms ,经历了 CRT 植入。TDI 在每个可存取的 LV 地点在 BVP 期间从三个顶端的看法被获得, SLD 在 BVP 期间被导出。由 SLD 的 Synchronicity 获得索引(Sg ) 是被定义(1+( 在基线的 SLD - 在 BVP 的 SLD ) 在基线的 /SLD ).Results 72 个地点被学习。积极再同步(R+ , Sg > 1 ) 在 42 被发现(58%) 地点。R+ 是更可能的在比前面的 LV 地点以后或侧面(66% 对 36% , P < 0.001 ) 。有 R+ 的实验 LV 铅培植地点和地点的词语索引是 50%(7/14 ) 由 BVP 的尖锐 LV 再同步的度取决于的 .Conclusions LV 铅地点和 LV 铅的实验培植与 R+ 导致仅仅 50% 词语索引。在 CRT 培植期间执行 TTE 是可行的与积极再同步识别 LV 地点。 | CHAN Ngai-yin CHOY Chi-chung CHEUNG Kar-chun LAU Chun-leung LO Ying-keung CHU Pui-shan YUEN Ho-chuen LAU Suet-ting CHOI Yuen-choi | 2010 | Chinese Medical Journal2010，，13： | 2 |
| 6 | Tibetan tectonic evolution inferred from spatial and temporal variations in post-collisional magmatism显示文摘 | Sun-Lin Chung Mei-Fei Chu Yuquan Zhang Yingwen Xie Ching-Hua Lo Tung-Yi Lee Ching-Ying Lan Xianhua Li Qi Zhang Yizhao Wang | 2004 | Earth Science Reviews2004，，3： | 2 |
| 7 | A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model显示文摘 | Henderson WR Jr Tang LO Chu SJ | 2002 | Am J Respir Crit Care Med2002，165，1： | 1 |
| 8 | Randomized trial on fluorides and sealants for fissure caries prevention显示文摘 | Liu BY Lo EC Chu CH | 2012 | J Dent Res2012，91，8： | 1 |
| 9 | A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model显示文摘 | Henderson WR Tang LO Chu SJ | | 0，，： | 1 |
| 10 | Activities of hydrocolloids as inhibitors of acrylamide formation in model systems and fried potato strips显示文摘 | Xiaohui Zeng Ka-Wing Cheng Yegang Du Ricky Kong Clive Lo Ivan K. Chu Feng Chen Mingfu Wang | 2010 | Food Chemistry2010，，2： | 1 |
| 11 | Solution structure of human P1*P2 heterodimer provides insights into the role of eukaryotic stalk in recruiting the ribosome-inactivating protein trichosanthin to the ribosome显示文摘 | Lee KM Yusa K Chu LO | 2013 | Nucleic Acids Res2013，41，18： | 1 |
| 12 | Adakites from continental collision zones: Melting of thickened lower crust beneath southern Tibet 显示文摘 | Chung S L Liu D Y Ji J Q Chu M F Lee H Y Wen D J Lo C H Lee T Y Qian Q Zhang Q | 2003 | Geology2003，31，11： | 1 |
| 13 | Petrogenesis of post-orogenic syenites in the Sulu Orogenic Belt, East China: geochronological, geochemical and Nd-Sr isotopic evidence 显示文摘 | Yang Jin-hui Chung Sun-lin Wilde S A Wu Fu-yuan Chu Mei-fei Lo Ching-hua Fan Hong-rui | 2005 | Chemical Geology2005，214，12： | 1 |
| 14 | One-step QFD based 3D morphological charts for concept generation of product variant design显示文摘 | LO C H TSENG K C CHU C H | 2010 | Expert Systems with Applications2010，37，11： | 1 |
| 15 | A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model 显示文摘 | Henderson WR Jr Tang LO Chu SJ Tsao SM Chiang GK Jones F Jonas M Pae C Wang H Chi EY | 2002 | Am J Respir Crit Care Med2002，165，1： | 1 |
| 16 | Caries status of preschool children in Hong Kong显示文摘 | Chu CH Fung DSH Lo ECM | 1999 | Br Dent J1999，187，： | 1 |
| 17 | Radiological prognosticators of hepatocellular carcinoma treated by hepatectomy显示文摘BACKGROUND: Hepatectomy is the main curative treatment for hepatocellular carcinoma (HCC), but postoperative long- term survival is poor. Preoperative radiological features of HCC displayed by computed tomography or magnetic resonance imaging could serve as additional prognostic factors. This study aimed to identify preoperative radiological features of HCC that may be of prognostic significance in hepatectomy. METHODS: Ninety-two patients who underwent hepatectomy for HCC were included in this study. Preoperative radiological features including tumor number, size, location (peripheral, middle, central), portal vein invasion, hepatic vein invasion, and presence of pseudo-capsule were analyzed in relation to survival. RESULTS: With a median follow-up period of 41.7 months, the 1-, 3- and 5-year overall survival rates were 85%, 65% and 58%, respectively. Univariate analysis showed that portal vein invasion and absence of pseudo-capsule were significant prognostic factors for overall survival, while all the examined radiological features were prognostic factors for disease-free survival. Multivariate analysis for overall survival found no significant factor. On multivariate analysis for disease-free survival, patients who had tumors with portal vein invasion had poorer survival with a hazard ratio of 2.26 (95% CI, 1.05-4.91; P=0.038) and patients with single nodular HCC or pseudo-capsulated HCC had better survival with a hazard ratio of 0.50 (95% CI, 0.27-0.94; P=0.032) and 0.38 (95% CI, 0.14-0.99; P=0.048), respectively. CONCLUSIONS: Demonstrable pseudo-capsule of HCC and solitary HCC on imaging and absence of portal vein invasionare features associated with better disease-free survival after hepatectomy. These features may guide treatment planning for HCC. | Kevin KW Chu See Ching Chan Sheung Tat Fan Kenneth SH Chok Tan To Cheung William W Sharr Albert CY Chan Chung Mau Lo | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，6： | 1 |
| 18 | The structure of the alkaloid sinoacutine显示文摘 | Shu J S Lo S Y Chu J H | 1964 | Scientia Sinica1964，13，12： | 1 |
| 19 | Epidemiology of rifampin ADP-ribosyltransferase(arr-2)and metallo-β-lactamase(bla_(IMP-4) gene cassettes in class 1 integrons in Acinetobacter strains isolated from blood cultures in 1997 to 2000显示文摘 | Houang E T Chu Y W Lo W S | 2003 | Antimicrob Agents Chemother2003，47，4： | 1 |
| 20 | A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model显示文摘 | Henderson WR JR Tang LO Chu SJ | 2002 | Am J Respir Crit Care Med2002，165，： | 1 |
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