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106篇 您的检索式:作者名="Christopoulos D"
    题名 作者 年代 出处 被引量
1向在人的察觉到钙的受体的 allosteric 药的结构的理解显示文摘allosterically 指向人的察觉到钙的受体(CaSR ) 的药有实质的治疗学的潜力,但是当前被限制。给 CaSR 的高分辨率的结构的缺席,我们把 mutagenesis 与一条新奇分析途径并且开发 “ 的分子的建模相结合; enriched”为在 Ca 2+ 在 CaSRs 7 transmembrane (7TM ) 以内的 o 和 allosteric 调节的人领域。修改多重有约束力的地点以适应在结构上的一个扩大的洞多样的 ligands 被识别。Phenylalkylamines 绑在与通常认为的 Ca 2+ o -binding 地点并且向一个细胞外的门厅延长。相反,在结构上和 pharmacologically 不同的 AC-265347 在 7TM 领域以内更深绑。而且,不同氨基酸网络被发现调停由不同调节的人的 cooperativity。这些调查结果可以与不同、潜在地偏导小径的药理学效果便于 allosteric 调节的人的合理设计。Katie Leach Karen J Gregory Irina Kufareva Elham Khajehali Anna E Cook Ruben Abagyan Arthur D Conigrave Patrick M Sexton Arthur Christopoulos 2016Cell Research2016,26,5:2
2Financial devel- opment and economic growth: evidence from panel unit root and eointegration tests 显示文摘Christopoulos D K Tsionas E G 2004Journal of Development Econom- ics2004,73,1:1
3Testing for Granger (non)-Causality in a time varying coefficient VAR model显示文摘Christopoulos D Le6n-Ledesma M 2008Journal of Forecasting2008,27,4:1
4paihogenesis of venous ulceration in relation to the calt muscle pump function显示文摘Christopoulos D Nicolaioles AN cook A 1989sugery1989,,:1
5Biology of vas- cular endothelial growth factor and its receptors in head and neck cancer: Beyond angiogenesis显示文摘Christopoulos A Ahn S M Klein J D 2011Head Neck2011,33,8:1
6Myomectomy during cesarean section:a safe procedure?显示文摘Hassiakos D Christopoulos P 2006Ann N Y Acad Sci2006,1092,:1
7Myomectomyduring cesareau section:a safe procedure显示文摘Hassiakcs D Christopoulos P Vitoratos N 2006Ann NY Acad Sci2006,1092,:1
8Percutaneous intervention of circumflex chronic total occlusions is associated with worse procedural outcomes:Insights From a Multicentre US Registry显示文摘Christopoulos G Karmpaliotis D Wyman MR 2014Can J Cardiol2014,30,12:1
9Nanoparticle-based DNA biosensor for visual detection of genetically modified organisms显示文摘Kalogianni D P Koraki T Christopoulos T K 2006Biosensors and Bioelectronics2006,21,:1
10Analytical formulation for the shielding effectiveness of enclosures with apertures 显示文摘Robinson M P Benson T M Christopoulos C D 1998IEEE Trans on Electromagnetic Compatibility1998,40,8:1
11Myomectomy during cesarean section:a safe procedure显示文摘Hassiakos D Christopoulos P Vitoratos N 2006Ann N Y Acad Sci2006,109,2:1
12Myomec- tomy during cesarean section:a safe procedure? 显示文摘Hassiakos D Christopoulos P Vitoratos N 2006Ann N Y Acad Sci2006,1092,:1
13Financial development and economic growth:evidence from panel unit root and cointegration test显示文摘 TSIONAS E G 2004Journal of development economics2004,73,1:1
14Financial development and economic growth: Evidence from panel unit root and cointegration Tests 显示文摘Christopoulos D K Tsionas E G 2004Journal of Development Econom- ics2004,73,:1
15Lossless region of interest coding显示文摘Nister D Christopoulos C A 0,,:1
16Financial Development and Economic Growth: Evidence from Panel Unit Root and Cointegration Tests显示文摘Christopoulos D K Tsionas E G 2004Journal of Development Economics2004,73,:1
17Effectiveness of simple approaches in mitigating residual deformations in buildings 显示文摘Pettinga D Christopoulos C Pampanin S 2007Earthquake Engineering and Structural Dynamics2007,36,12:1
18Myomectomy (lur-ing cesarean section ; a safe procedure 显示文摘Hassiakos D Christopoulos P Vitoratos N 2006Ann N Y A(、ad Sci2006,1092,:1
19Upper eyelid island orbicularis oculi myocutaneous flap for periorbital reconstrnction显示文摘Porfiris E Kalokerinos D Christopoulos A 2000Ophthal Plast Reconstr Surg2000,16,1:1
20查看详情显示文摘Feltin E Christmann G Dorsaz J Castiglia A Carlin J F Butte R Grandjean N Christopoulos S Baldassarri G Hogersthal H V Grundy A J D Lagoudakis P G Baumberg J J 0,,:1
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