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5篇 您的检索式:作者名="Christopher Yeh"
    题名 作者 年代 出处 被引量
1Over-expression of fibroblast growth factor receptor 3 in human hepatocellular carcinoma显示文摘AIM: To describe the significant over-expression of fibroblast growth factor receptor 3 (FGFR3), which is a signal transduction and cell proliferation related gene in hepatocellular carcinoma (HCC).METHODS: Following DNA microarray, Northern blot and quantitative real-time PCR were employed to confirm FGFR3 expression difference in HCC tissues and surrounding non-neoplastic liver tissue. FGFR3 expression levels were further determined by immunohistochemical study in 43 cases of HCC.RESULTS: Northern blot results showed the significant over-expression of FGFR3 in HCC tissues, which was consistent with that from DNA microarray. Quantitative real-time PCR demonstrated that the mean ratio of FGFR3 mRNA to glyceraldehyde-3-phosphate dehydrogenase (GADPH) mRNA in HCC tissue was 0.250, whereas the ratio in non-neoplastic liver tissue was 0.014. Statistical analyses of 43 cases of HCC revealed that HCC scored higher than the matched non-neoplastic liver tissues.Examination of clinicopathological features revealed a strong correlation of over-expression of FGFR3 with poor tumor differentiation and high nuclear grade.CONCLUSION: Over-expression of FGFR3 may play an important role in liver carcinogenesis. FGFR3 may be an ideal candidate as a molecular marker in the diagnosis of HCC and a potential therapeutic target.Wei-Hua Qiu Bing-Sen Zhou Peiguo G. Chu Wen-Gang Chen Christopher Chung Jennifer Shih Paul Hwu Christopher Yeh Richard Lopez Yun Yen 2005World Journal of Gastroenterology2005,11,34:8
2Deep greenhouse gas reduction scenarios for California – Strategic implications from the CA-TIMES energy-economic systems model显示文摘David McCollum Christopher Yang Sonia Yeh Joan Ogden 2011Energy Strategy Reviews2011,,1:1
3Dietary marine lipids suppress continuous expression of interleukin-1β gene transcription1显示文摘Dwight R. Robinson Masaharu Urakaze Riyun Huang Hirofumi Taki Eiji Sugiyama Christopher T. Knoell LiLian Xu Edward T. H. Yeh Philip E. Auron 1996Lipids1996,,1:1
4Long‐term follow‐up of the treatment of renal angiomyolipomas after selective arterial embolization with alcohol显示文摘Christopher M.Chick Bien‐SooTan ChristopherCheng ManishTaneja RichardLo Yeh‐HongTan Shueh‐EnLin Kiang‐HiongTay 2010BJU International2010,,3:1
5The protein infommfion resource显示文摘Cathy HW Yeh LSL Christopher RM 2003Nucleic Acids Res2003,31,:1
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