|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Review: Improving our knowledge of male mosquito biology in relation to genetic control programmes显示文摘 | Rosemary Susan Lees Bart Knols Romeo Bellini Mark Q. Benedict Ambicadutt Bheecarry Hervé Christophe Bossin Dave D. Chadee Jacques Charlwood Roch K. Dabiré Luc Djogbenou Alexander Egyir-Yawson René Gato Louis Clément Gouagna Mo’awia Mukhtar Hassan Shakil A | 2013 | Acta Tropica2013，，： | 2 |
| 2 | Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial显示文摘 | Marcia S Brose Christopher M Nutting Barbara Jarzab Rossella Elisei Salvatore Siena Lars Bastholt Christelle de la Fouchardiere Furio Pacini Ralf Paschke Young Kee Shong Steven I Sherman Johannes W A Smit John Chung Christian Kappeler Carol Pe?a István Mo | 2014 | The Lancet2014，，： | 1 |
| 3 | Zika virus in Gabon(Central Africa)-2007:a new threat from Aedes albopictus?显示文摘 | Grard G Mélanie C Illich Manfred M DieudonnéN Statiana MO Davy J Didier F Christophe P Eric Maurice L | 2014 | PLoS Negl Trop Dis2014，8，2： | 1 |
| 4 | Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations显示文摘 | Britta Will Li Zhou Thomas O. Vogler Susanna Ben-Neriah Carolina Schinke Roni Tamari Yiting Yu Tushar D. Bhagat Sanchari Bhattacharyya Laura Barreyro Christoph Heuck Yonkai Mo Samir Parekh Christine McMahon Andrea Pellagatti Jacqueline Boultwood Cristina | 2012 | Blood2012，，10： | 1 |
| 5 | An Integrated Process Model Driven Knowledge Based System for Remote Customer Support 显示文摘 | John P T Mo Christopher Menzel | 1998 | Computers inIndustry1998，，37： | 1 |
| 6 | Quantitative metabolic profiles of tomato flesh and seeds during fruit development: complementary analysis with ANN and PCA显示文摘 | Fabien Mounet Martine Lemaire-Chamley Micka?l Maucourt Cécile Cabasson Jean-Luc Giraudel Catherine Deborde René Lessire Philippe Gallusci Anne Bertrand Monique Gaudillère Christophe Rothan Dominique Rolin Annick Moing | 2007 | Metabolomics2007，，3： | 1 |
| 7 | An integrated progress model driven knowledge based system for remote customer support显示文摘 | Christopher Menzel | 1996 | Computer in Industry1996，4，15： | 1 |
| 8 | An Intergrated ProcessModel Driven Knowledge Based System for Remote CustomerSupport显示文摘 | MO Jone P T MENZAL Christopher | 1998 | Computers in Industry1998，37，3： | 1 |
| 9 | Quantitative metabolic profiles of tomato flesh and seeds during fruit development: complementary analysis with ANN and PCA显示文摘 | Fabien Mounet Martine Lemaire-Chamley Micka?l Maucourt Cécile Cabasson Jean-Luc Giraudel Catherine Deborde René Lessire Philippe Gallusci Anne Bertrand Monique Gaudillère Christophe Rothan Dominique Rolin Annick Moing | 2007 | Metabolomics2007，，3： | 1 |
| 10 | Depression and cardiovascular disease:mechanisms of interaction显示文摘 | Karen EJ David JW Christopher MO | 2003 | Biol Psychiatry2003，54，： | 1 |
| 11 | Measles Virus Genoty- ping by Nucleotide-Specific Multiplex PCR 显示文摘 | I Jacques RK Fred Fack Christophe MO | 2004 | J Clin Microbiol2004，42，7： | 1 |
| 12 | TIMP independence of matrix metalloproteinase (MMP) -2 activation by mem- brane type 2 ( MT2 ) - MMP is determined by contribu- tions of both the MT2 - MMP catalytic and hemopexin C domains显示文摘 | Charlotte JM Christopher MO | 2006 | J Biol Chem2006，281，26： | 1 |
| 13 | An integrated process model driven knowledge based system for remote customer support 显示文摘 | Mo John P T Menzel Christopher | 1998 | Computers in Industry1998，37，2： | 1 |
| 14 | An integrated process model driven knowledge based system for remotecustomer support 显示文摘 | John P T Mo Christopher Menzel | 1998 | Computer in Industry1998，37，3： | 1 |
| 15 | Yucel CT of Coronary Artery Disease显示文摘 | Schoepf UJ Christoph RB Bernd MO | 2004 | Radiology2004，232，1： | 1 |
| 16 | An integrated process model driven knowledge based system for remote customer support显示文摘 | John P T Mo Christopher Menzel | 1998 | Computer in Industry1998，37，3： | 1 |
| 17 | INFLUENCE OF THE Rh (D) BLOOD GROUP SYSTEM ON GRAFT SURVIVAL IN RENAL TRANSPLANTATION显示文摘 | Christopher F. Bryan Stanley I. Mitchell Hung Mo Lin Paul W. Nelson Charles F. Shield Alan M. Luger George E. Pierce Gilbert Ross Bradley A. Warady Mark I. Aeder Thomas S. Helling Michael D. Landreneau Kevin M. Harrell | 1998 | Transplantation1998，，4： | 1 |
| 18 | Prognostic impact of MMP‐2 and MMP‐9 expression in pathologic stage IA non‐small cell lung cancer 显示文摘 | Wenlong Shao Wei Wang Xin‐guo Xiong Christopher Cao Tristan D. Yan Guoqin Chen Hanzhang Chen Weiqiang Yin Jun Liu Yingying Gu Mingcong Mo Jianxing He | 2011 | J. Surg. Oncol2011，，： | 1 |
| 19 | Transgenerational bone toxicity in F3 medaka (Oryzias latipes) induced by ancestral benzo[a]pyrene exposure: Cellular and transcriptomic insights显示文摘Benzo[a]pyrene(BaP),a ubiquitous pollutant,raises environmental health concerns due to induction of bone toxicity in the unexposed offspring.Exposure of F0 ancestor medaka(Oryzias latipes)to 1μg/L BaP for 21 days causes reduced vertebral bone thickness in the unexposed F3 male offspring.To reveal the inherited modifications,osteoblast(OB)abundance and molecular signaling pathways of transgenerational BaP-induced bone thinning were assessed.Histomorphometric analysis showed a reduction in OB abundance.Analyses of the miRNA and mRNA transcriptomes revealed the dysregulation of Wnt signaling(frzb/ola-miR-1–3p,sfrp5/ola-miR-96–5p/miR-455–5p)and bone morphogenetic protein(Bmp)signaling(bmp3/ola-miR-96–5p/miR-181b-5p/miR-199a-5p/miR-205–5p/miR-455–5p).Both pathways are major indicators of impaired bone formation,while the altered Rank signaling in osteoclasts(c-fos/miR-205–5p)suggests a potentially augmented bone resorption.Interestingly,a typical BaP-responsive pathway,the Nrf2-mediated oxidative stress response(gst/ola-miR-181b-5p/miR-199a-5p/miR-205),was also affected.Moreover,mRNA levels of epigenetic modification enzymes(e.g.,hdac6,hdac7,kdm5b)were found dysregulated.The findings indicated that epigenetic factors(e.g.,miRNAs,histone modifications)may directly regulate the expression of genes associated with transgenerational BaP bone toxicity and warrants further studies.The identified candidate genes and miRNAs may serve as potential biomarkers for BaP-induced bone disease and as indicators of historic exposures in wild fish for conservation purposes. | Jiezhang Mo Miles Teng Wan DorisWai-Ting Au Jingchun Shi Nathan Tam Xian Qin Napo K.M.Cheung Keng Po Lai Christoph Winkler Richard Yuen-Chong Kong Frauke Seemann | 2023 | Journal of Environmental Sciences2023，，5： | 0 |
| 20 | 依据清创术后细菌培养结果确定开放骨折创面关闭时机显示文摘背景:目前,对开放骨折创面缝合关闭的时机尚没有客观的标准。许多学者对于开放骨折创面缝合关闭最佳时机提出了各种各样的建议,但均依据主观评判的参数。本研究的目的是应用前瞻性方法,在四肢开放骨折清创和冲洗木后,依据创面细菌培养结果来指导创面的缝合关闭时机。方法:本组对422例急诊开放骨折患者,进行了创面清创冲洗、骨折固定和开放创面处理。清创术后创面采样进行厌氧菌和有氧菌培养。清创术后48h,患者再次手术。如果初次细菌培养结果为阳性,则再次进行冲洗和清创术,之后再次留取菌培样本。创面不关闭直到细菌培养结果为阴性为止,否则重复进行冲洗和清创术。结果:在422例开放骨折中,有346例获得了长期随访。全组创面深部感染率为4|3%。GustiloⅡ型开放骨折创面深部感染率为4%,GustiloⅢ型开放骨折为5.7%。在GustiloⅢ型开放骨折中,依骨折类型不同,感染率出现变化,GustiloⅢA型开放骨折为1.8%,GustiloⅢB型开放骨折为10.6%,GustiloⅢC型开放骨折为20%。需要反复清创的骨折患者,伴有糖尿病患者以及体重指数增加的患者,感染率均出现上升。研究数据表明,开放骨折在菌培阳性条件下关闭创面(违反本研究原则)并未显著增加深部感染风险(p=0.0501)。结论:采用本文提出的标准处理方法,与历史对照方法相比,开放骨折深部感染率降到很低。但取得这样结果是以增加冲洗和清创术次数为代价。可信水平:治疗性研究Ⅳ级。关于证据等级的完整描述详见投稿须知。 | Christopher J. Lenarz, MD J. Tracy Watson, MD Berton R. Moed, MD Heidi Israel, PhD, RN J. Daniel Mullen MSPH, BA, BS James B. MacDonald, BS 叶伟胜(译) | 2011 | 中华骨科杂志2011，31，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员