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| 1 | Liver stiffness in the hepatitis B virus carrier:A non-invasive marker of liver disease influenced by the pattern of transaminases显示文摘AIM: To investigate the usefulness of transient elastography by Fibroscan (FS),a rapid non-invasive technique to evaluate liver fibrosis,in the management of chronic hepatitis B virus (HBV) carriers.METHODS: In 297 consecutive HBV carriers,we studied the correlation between liver stiffness (LS),stage of liver disease and other factors potentially influencing FS measurements.In 87 chronic hepatitis B (CHB) patients,we monitored the FS variations according to the spontaneous or treatment-induced variations of biochemical activity during follow-up.RESULTS: FS values were 12.3 ± 3.3 kPa in acute hepatitis,10.3 ± 8.8 kPa in chronic hepatitis,4.3 ± 1.0 kPa in inactive carriers and 4.6 ± 1.2 kPa in blood donors.We identified the cut-offs of 7.5 and 11.8 kPa for the diagnosis of fibrosis ≥ S3 and cirrhosis respectively,showing 93.9% and 86.5% sensitivity,88.5% and 96.3% specificity,76.7% and 86.7% positive predictive value (PPV),97.3% and 96.3% negative predictive value (NPV) and 90.1% and 94.2% diagnostic accuracy.At multivariate analysis in 171 untreated carriers,fibrosis stage (t = 13.187,P < 0.001),active vs inactive HBV infection (t = 6.437,P < 0.001),alanine aminotransferase (ALT) (t = 4.740,P < 0.001) and HBV-DNA levels (t = -2.046,P = 0.042) were independently associated with FS.Necroinflammation score (t = 2.158,> 10/18 vs ≤ 10/18,P = 0.035) and ALT levels (t = 3.566,P = 0.001) were independently associated with LS in 83 untreated patients without cirrhosis and long-term biochemical remission (t = 4.662,P < 0.001) in 80 treated patients.During FS monitoring (mean follow-up 19.9 ± 7.1 mo) FS values paralleled those of ALT in patients with hepatitis exacerbation (with 1.2 to 4.4-fold increases in CHB patients) and showed a progressive decrease during antiviral therapy.CONCLUSION: FS is a non-invasive tool to monitor liver disease in chronic HBV carriers,provided that the pattern of biochemical activity is taken into account.In the inactive carrier,it identifies non-HBV-related causes of liver damage and transient reactivations.In CHB patients,it may warrant a more appropriate timing of control liver biopsies. | Filippo Oliveri Barbara Coco Pietro Ciccorossi Piero Colombatto Veronica Romagnoli Beatrice Cherubini Ferruccio Bonino Maurizia Rossana Brunetto | 2008 | World Journal of Gastroenterology2008，14，40： | 43 |
| 2 | 贡嘎山地区不同海拔冷杉比叶质量和非结构性碳水化合物含量变化显示文摘以贡嘎山地区磨西山谷东北坡和康定山谷西南坡为样地,研究了高山林线和低海拔冷杉休眠期和生长旺盛期针叶比叶质量和组织非结构性碳水化合物含量.结果表明:生长在温暖湿润的磨西山谷东北坡的冷杉针叶比叶质量和组织非结构性碳水化合物含量均高于炎热干燥的康定山谷西南坡;高山林线冷杉比叶质量大于低海拔冷杉;高山林线冷杉组织非结构性碳水化合物含量总体高于低海拔冷杉,且生长期比休眠期更为显著.研究结果不支持'碳供应不足导致高山林线形成'的假说. | 李蟠 孙玉芳 王三根 王小丹 蔡小虎 朱万泽 Cherubini Paolo 李迈和 | 2008 | 应用生态学报2008，19，1： | 24 |
| 3 | Prioritizing sustainable development goals and linking them to ecosystem services:A global expert’s knowledge evaluation显示文摘The implementation of strategies to achieve the Sustainable Development Goals(SDGs)is frequently hindered by potential trade-offs between priorities for either environmental protection or human well-being.However,ecosystem services(ES)-based solutions can offer possible co-benefits for SDGs implementation that are often overlooked or underexploited.In this study,we cover this gap and investigate how experts from different countries value the SDGs and relate them with ES.A total of 66 countries participated to the survey,and answers were grouped into three macro-regions:Asia;Europe,North America,and Oceania(ENO);Latin America,Caribbean and Africa(LA).Results show that the most prioritized SDGs in the three macro-regions are usually those related to essential material needs and environmental conditions,such as SDG2(Zero Hunger),SDG1(No Poverty),and SDG6(Clean Water).At a global scale,the number of prioritized synergies between SDGs and ES largely exceeded trade-offs.The highest amount of synergies was observed for SDG1(No Poverty),mainly with SDG2,SDG3(Good Health),SDG5(Gender Equality),and SDG8(Economic Growth).Other major synergies among SDGs include SDG14-15(Life below water-Life on land),SDG5-10(Gender Equity-Reduced Inequality),and SDG1-2(No poverty-Zero Hunger).At a global scale,SDG15,SDG13,SDG14,and SDG6 were closely related to ES like climate regulation,freshwater,food,water purification,biodiversity,and education.SDG11(Sustainable Cities)and SDG3 were also relevant in Asia and in LA,respectively.Overall,this study shows the potential to couple future policies that can implement SDGs’strategies while adopting ES-based solutions in different regions of the world. | Siqi Yang Wenwu Zhao Yanxu Liu Francesco Cherubini Bojie Fu Paulo Pereira | 2020 | Geography and Sustainability2020，1，4： | 9 |
| 4 | Integrate ecosystem services into socio-economic development to enhance achievement of sustainable development goals in the post-pandemic era显示文摘The COVID-19 pandemic has stalled and rolled back progress on Sustainable Development Goals(SDGs).Ecosys-tem services(ESs),defined as the contributions of ecosystems to human well-being,underpin the achievement of SDGs.To promote SDG achievement in post-pandemic era,we teased out the links between ESs and SDGs while examining the impact of COVID-19.We found that ESs benefited all SDGs,yet man-made pressures led to degra-dation of ecosystems and their services.There is broad consensus that the virus lurks in degraded ecosystems and generates spillover due to human interference.The pandemic and global lockdown/restriction disrupted the flow of ESs and altered human ESs demand,threatening the efforts for the SDGs.We suggested:1)to study the association and traceability of ESs-SDGs under the pandemic;2)to prioritize pressing issues such as health care,livelihood,and resource security and in the long run,we should promote human-nature harmony to achieve the SDGs;and 3)to enhance ESs and to promote the SDGs through local community efforts,ESs accounting,and ecosystem restoration.This paper provides insights into the importance of ESs to the SDGs and the ways to integrate ESs into socio-economic development to promote the SDG achievement after the pandemic. | Caichun Yin Wenwu Zhao Francesco Cherubini Paulo Pereira | 2021 | Geography and Sustainability2021，2，1： | 8 |
| 5 | 人为气溶胶排放导致最近80年东亚夏季风在过去四个世纪以来空前减弱显示文摘亚洲夏季风(Asian Summer Monsoon,ASM)对亚洲数十亿人口的生存、亚洲生态系统和生物多样性的分布、以及农业生产(粮食安全)和工业活动影响严重。因此了解ASM过去时空变化及其动力学过程对陆地生态系统、水资源、森林和景观研究至关重要。近几十年,器测记录显示以降水量为代表的ASM强度一直在减弱,但这一减弱趋势的起始时间和动力学过程尚不清楚。为此,第一次集成了ASM西部-中部边缘带10个对降水敏感的树木年轮宽度年表,重建了公元1566年以来反映ASM强度变化的降水序列。重建结果不仅捕捉到了ASM过去4个世纪以来强弱变化历史,也反映出历史上蝗灾与弱季风的关联。特别是发现了最近80年具有过去448年中前所未有的、最为强烈的、显著且持续时间最长的ASM强度减弱趋势。这一减弱趋势与在温室效应影响下ASM本该增强的预期大相庭径。耦合气候模型实验表明,北半球人为硫酸盐气溶胶排放的逐渐增加,对ASM减弱起了决定性作用。 | 刘禹 蔡文炬 孙长峰 宋慧明 Kim MCobb 李建平 Steven WLeavitt 吴立新 蔡秋芳 刘若时 Benjamin Ng Paolo Cherubini Ulf Büntgen 宋怡 王国建 雷莺 晏利斌 李强 马永永 方丛羲 孙军艳 李旭祥 Deliang Chen Hans WLinderholm | 2019 | 地球环境学报2019，10，6： | 7 |
| 6 | 日本柳杉生长对气候的响应显示文摘对建立的日本柳杉的差值年表与气象数据进行的相关性分析结果表明:日本柳杉的生长与上年10、11月的温度,与上年12月、当年1月的降水量正相关;与当年3月的降水量、8月的温度负相关。这既是日本柳杉海拔分布的重要因子,也是影响林分生物生产力和碳循环的重要因素。 | 蔡小虎 李迈和 Paolo Cherubini 蒲春林 | 2006 | 四川林业科技2006，27，3： | 7 |
| 7 | Coupling trade-offs and supply-demand of ecosystem services(ES):A new opportunity for ES management显示文摘The trade-offs and supply-demand relations of ecosystem services(ES)are at the frontier of geographical and ecological studies.However,previous studies have focused on either trade-offs or the supply-demand aspects,while ES conflicts and supply/demand contradictions have not been comprehensively examined.The relation-ship between ES trade-offs and supply-demand is logically valid and studying the coupling of both can provide approaches for simultaneously alleviating ES conflicts and supply-demand contradictions.This study,based on a review of previous analyses of ES trade-offs and supply-demand dynamics,proposes a new analytic framework to couple them.First,we define two types of trade-offs based on the directions of growth or decline of the two ser-vices.We also define the supply-demand balance area and the supply-demand risk area according to the ES flow characteristics.Second,the mechanisms driving ES trade-offs are clarified,and land-use scenarios are set based on the mechanisms.Third,the supply-demand spatial characteristics of ES are analyzed,and supply-demand risk areas are identified.Finally,scenario iterations are performed to minimize the supply-demand risk area at an acceptable trade-offintensity to identify an optimal land use plan,which simultaneously alleviates ES conflicts and supply-demand contradictions.This analytic framework offers new opportunities for improving sustainable ecosystem management. | Qiang Feng Wenwu Zhao Baoling Duan Xiangping Hu Francesco Cherubini | 2021 | Geography and Sustainability2021，2，4： | 3 |
| 8 | Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers显示文摘 | FERRUCCI L CHERUBINI A BANDINELLI S | 2006 | J Clin Endocrinol Metab2006，91，2： | 1 |
| 9 | Uric acid and inflammatory markers显示文摘 | Ruggiero C Cherubini A Ble A | 2006 | Eur Heart J2006，27，11： | 1 |
| 10 | Filtered Multitone Modulation for very high-speed digital subscriber显示文摘 | G Cherubini E Eleftheriou S Olcer J Cioffi | 2000 | IEEE Commun Magazine2000，，： | 1 |
| 11 | Genetic diversity in European Chestnut populations by means of genomic and genic microsatellite markers显示文摘 | Martin MA Mattioni C Cherubini M | 2010 | Tree Genetics & Genomes2010，6，5： | 1 |
| 12 | Filtered multitone modulation for very high-speed digital subscriber lines显示文摘 | CHERUBINI G ELEFTHERIOU E OLCER S | 2002 | IEEE J Select Areas Commun2002，20，5： | 1 |
| 13 | Uric acid and inflammatory markers显示文摘 | Ruggiero C Cherubini A Ble A | 2006 | Eur Heart J2006，27，10： | 1 |
| 14 | Tree ring from a European beech forest chronology are useful for detecting growth trends and carbon sequestration显示文摘 | Basietto M Cherubini P Scarescia-Mugnozza G | 2004 | Canadian Journal of Forest res earch2004，34，2： | 1 |
| 15 | Hepatitis B surface antigen serum levels help to distinguish active from inactive hepatitis B virus genotype D carriers 显示文摘 | Brunetto MR Oliveri F Colombatto P Moriconi F Ciccorossi P Coco B Romagnoli V Cherubini B Moscato G Maina AM Cavallone D Bonino F | 2010 | Gastroenterology2010，139，2： | 1 |
| 16 | Impact Assessment of Biodiversity and Carbon Pools from Land Use and Land Use Changes in Life Cycle Assessment,Exemplified with Forestry Operations in Norway显示文摘 | MICHELSEN O CHERUBINI F STROMMAN A H | 2012 | Journal of Industrial Ecology2012，16，2： | 1 |
| 17 | Uric acid and inflammatory markers 显示文摘 | RUGGIERO C CHERUBINI A BLE A | 2006 | Eur Heart J2006，27，10： | 1 |
| 18 | Filter bank modulation techniques for very high speed digital subscriber lines显示文摘 | CHERUBINI G ELEFTHERIOUS E OLCER S CIOFFI J M | 2000 | IEEE Commun Mag2000，38，5： | 1 |
| 19 | LCA of magnesium production:technological overview and worldwide estimation of environmental burdens显示文摘 | Francesco Cherubini Marco Raugei Sergio Ulgiati | | 0，，8： | 1 |
| 20 | Altered mitochondrial membrane fluidity in AD brain显示文摘 | Mecocci P Cherubini A Beal MF | 1996 | Neurosci Lett1996，207，2： | 1 |
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