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4篇 您的检索式:作者名="Chengkai Dai"
    题名 作者 年代 出处 被引量
1A multi-axis robot-based bioprinting system supporting natural cell function preservation and cardiac tissue fabrication显示文摘Despite the recent advances in artificial tissue and organ engineering,how to generate large size viable and functional complex organs still remains as a grand challenge for regenerative medicine.Three-dimensional bioprinting has demonstrated its advantages as one of the major methods in fabricating simple tissues,yet it still faces difficulties to generate vasculatures and preserve cell functions in complex organ production.Here,we overcome the limitations of conventional bioprinting systems by converting a six degree-of-freedom robotic arm into a bioprinter,therefore enables cell printing on 3D complex-shaped vascular scaffolds from all directions.We also developed an oil bath-based cell printing method to better preserve cell natural functions after printing.Together with a self-designed bioreactor and a repeated print-and-culture strategy,our bioprinting system is capable to generate vascularized,contractible,and long-term survived cardiac tissues.Such bioprinting strategy mimics the in vivo organ development process and presents a promising solution for in vitro fabrication of complex organs.Zeyu Zhang Chenming Wu Chengkai Dai Qingqing Shi Guoxin Fang Dongfang Xie Xiangjie Zhao Yong-Jin Liu Charlie CLWang Xiu-Jie Wang 2022Bioactive Materials2022,7,12:4
2Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis显示文摘Chengkai Dai Luke Whitesell Arlin B. Rogers Susan Lindquist 2007Cell2007,,6:1
3Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis显示文摘Chengkai Dai Luke Whitesell Arlin B. Rogers Susan Lindquist 2007Cell2007,,:1
4Heat shock factor 1 is a direct anti-amyloid factor:connecting neurodegeneration and uncontrolledgrowth显示文摘Worldwide,more than 40 million people are afflicted with Alzheimer's disease(AD)(Esquerda-Canals et al.,2017).AD is a devastating neurodegenerative disroder characterized by progressive decline in cognitive abilities.A hallmark of AD and other neurodegenerative disorders in humans is the aggregation of proteins into amyloid fibrils and their deposition into plaques and intracellular inclusions(Iadanza et al.)。Zijian Tang Chengkai Dai 2022Neural Regeneration Research2022,17,3:0
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