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| 1 | Analysis and Numerical Simulation of Rolling Contact between Sphere and Cone显示文摘In non-conforming rolling contact, the contact stress is highly concentrated in the contact area. However, there are some limitations of the special contact model and stress model used for the theoretical study of the phenomenon, and this has prevented in-depth analysis of the associated friction, wear, and failure. This paper is particularly aimed at investigating the area of rolling contact between a sphere and a cone, for which purpose the boundary is determined by the Hertz theory and the geometries of the non-conforming surfaces. The phenomenon of stick-slip contact is observed to occur in the contact area under the condition of no-full-slip(Q < μ·P). Using the two-dimensional rolling contact theory developed by CARTER, the relative positions of the stick and slip regions and the distribution of the tangential force over the contact area are analyzed. Furthermore, each stress component is calculated based on the Mc Ewen theory and the idea of narrow band. The stress equations for the three-dimensional rolling contact between the sphere and the cone are obtained by the principle of superposition, and are used to perform some numerical simulations. The results show that the stress components have a large gradient along the boundary between the stick and slip regions, and that the maximum stress is inversely proportional to the contact coefficient and proportional to the friction coefficient. A new method for investigating the stress during non-classical three-dimensional rolling contact is proposed as a theoretical foundation for the analysis of the associated friction, wear, and failure. | ZHAO Yanling XIA Chengtao WANG Hongbo XUAN Jiaping XIANG Jingzhong LIU Xianli SU Xiangguo | 2015 | Chinese Journal of Mechanical Engineering2015，28，3： | 18 |
| 2 | FATIGUE LIFE PREDICTION OF CRANKSHAFT MADE OF MATERIAL 48MnV BASED ON FATIGUE TESTS,DYNAMIC SIMULATION AND FEA显示文摘48MnV 的 S-N 曲线和疲劳参数用小样品测试和楼梯或沿着方法被获得,它为预言用 48MnV 做的机轴的疲劳生命铺平道路。一台六柱体的引擎的机轴的疲劳生活用象 S-N 方法那样的不同损坏模型,被计算正常紧张途径, Smoth-Watson-Topper (SWT )-Bannantine 途径,砍基于动态模拟和机轴的有限元素分析(FEA ) 拉紧途径,和 Fatemi-Socie 方法。结果显示传统的计算是保守的,如果机轴在它生命的结束以后被重新生产,机轴的剩余疲劳生活是足够的维持下个生命周期。 | ZHANG Guoqing PU Gengqiang WANG Chengtao | 2006 | Chinese Journal of Mechanical Engineering2006，19，2： | 13 |
| 3 | A comparative study of the osteogenic performance between the hierarchical micro/submicro-textured 3D-printed Ti6Al4V surface and the SLA surface显示文摘Three-dimensional(3D)printed titanium and its alloys have broad application prospect in the field of biomedical implant materials,although the biological performance of the original surface should be improved.Learning from the development experience of conventional titanium implants,to construct a hierarchical hybrid topological surface is the future direction of efforts.Since the original 3D-printed(3D hereafter)Ti6Al4V surface inherently has micron-scale features,in the present study,we introduced submicron-scale pits on the original surface by acid etching to obtain a hierarchical micro/submicro-textured surface.The characteristic and biological performance of the 3D-printed and acid-etched(3DA hereafter)surface were evaluated in vitro and in vivo,compared with the conventional sandblasted,large-grit,acid-etched(SLA hereafter)surface.Our results suggested the adhesion,proliferation and osteogenic differentiation of bone marrow derived mesenchymal stromal cells(BMSCs),as well as the in vivo osseointegration on 3DA surfaces were significantly improved.However,the overall osteogenic performance of the 3DA surface was not as good as the conventional SLA surface. | Jinkai Zhanga Jiaqiang Liu Chengtao Wang Fengshan Chen Xudong Wang Kaili Lin | 2020 | Bioactive Materials2020，5，1： | 8 |
| 4 | Enhanced Photocatalytic Degradation of Rhodamine B by Cu_2O Coated Silicon Nanowire Arrays in Presence of H_2O_2显示文摘Highly ordered Cu2 O coated silicon nanowire arrays(Si NWAs) were fabricated as photocatalyst via depositing Cu nanoparticles on silver-assisted electroless-etched Si NWAs and subsequently annealing. The as-prepared samples have been characterized by scanning electron microscopy, X-ray diffraction and UV e VIS e NIR spectrophotometry. The photocatalytic properties of the Cu2 O coated Si NWAs were investigated by degradation of Rhodamine B(Rh B) under simulated solar light with a cut-off filter(l > 420 nm). The results indicated that H2O2 could greatly improve the photocatalytic properties of Cu2 O coated Si NWAs, and exhibited strong synergy effect between them. The hybrid nanowire arrays will be promising photocatalytic materials in the field of energy and environment. | Chengtao Yang Jinliang Wang Lirun Mei Xiaoyu Wang | 2014 | Journal of Materials Science & Technology2014，30，11： | 7 |
| 5 | The synergistic effect of 3D-printed microscale roughness surface and nanoscale feature on enhancing osteogenic differentiation and rapid osseointegration显示文摘Personalized precision therapy and rapid osseointegration are the main development directions of dental implants.3 D printing is a vital advanced manufacturing technology for personalized precision therapy.However,the osteogenesis of the 3 D printed Ti6 Al4 V implants is unsatisfactory.From the bionic perspective,the hierarchical micro/nano-topography can mimic the microenvironment of the multilevel structure of natural bone tissue and may endow the implant surface with superior bioactivity.In the present study,the hierarchical micro/nano-topography was successfully fabricated by construction the nanoscale feature on 3 D printed microscale roughness surface of 3 D-printed Ti6 Al4 V implants by alkali-heat treatment and hydrothermal treatment.Then the cell biological responses in vitro and osseointegration performance in vivo were systematically evaluated.The hierarchical micro/nano-topography evidently increased the roughness,improved the hydrophilicity and accelerated the hydroxyapatite deposition and mineralization,which significantly enhanced the adhesion,differentiation and extracellular matrix mineralization of bone marrow derived mesenchymal stromal cells(BMSCs).Most importantly,the hierarchical micro/nano-topography on 3 D-printed implants facilitated the new bone formation and rapid osseointegration in vivo.Our study suggested that 3 D-printed implant with micro/nano-topography may be a promising candidate to be applied in orthopedic field to meet the need of customized therapy and rapid osseointegration. | Hui Wang Jiaqiang Liu Chengtao Wang Steve Guofang Shen Xudong Wang Kaili Lin | 2021 | Journal of Materials Science & Technology2021，，4： | 5 |
| 6 | Hot deformation behavior and flow stress modeling of annealed AZ61 Mg alloys显示文摘In this study, the hyperbolic-sine type constitutive equation was used to model the flow stress of annealed AZ61 magnesium(Mg) alloys. Hot compression tests were conducted at the temperatures ranging from 250 1C to 450 1C and at the strain rates ranging from 1 10–3s 1to 1 s 1on a Gleeble-3500 thermo-simulation machine. Constitutive equations as a function of strain were established through a simple extension of the hyperbolic sine constitutive relation. The effects of annealing heat treatments on the variations in constitutive parameters with strain were discussed. The hot compressive flow curves exhibited typical features of dynamic recrystallization. Multiple peak flow curves were observed in the annealed specimens upon testing at a strain rate of 1 10 1s–1and at various temperatures. Variations in constitutive parameters with strain were related to flow behavior and dependent on the initial conditions of the test specimens. The flow stresses of annealed AZ61 Mg alloys were predicted well by the strain-dependent constitutive equations of the hyperbolic sine function under the deformation conditions employed in this study. | Chinghao Liao Horngyu Wu Chengtao Wu Fengjun Zhu Shyong Lee | 2014 | Progress in Natural Science:Materials International2014，24，3： | 4 |
| 7 | Forensic investigation of 23 autosomal STRs and application in Han and Mongolia ethnic groups显示文摘A forensic validation study of the Early Access HuaxiaTM Platinum Polymerase Chain Reaction (PCR) kit was completed to document the performance capabilities and limitations.The genotyping of DNA samples was consistent across a large range of template DNA concentrations,with complete profiles obtained at 0.125 ng;however,no more than 2 mm× 1.2 mm punches of samples would be recommended for direct amplification.The size precision and accuracy test revealed the genotyping ability;while consistent results were obtained when comparing the kit with other commercially available systems.In addition,the whole PCR amplification can finish within approximately 45 min,making the system suitable for fastdetection.However,only partial profiles may be obtained with challenging samples,including DNA stored on Foam-Tipped Applicators (FTA) cards or some case samples.For the forensic application in ethnic groups,a total of 282 and 229 alleles were obtained in Han and Mongolia,respectively.Since the 23 short tandem repeats were independent from each other,the cumulative power of exclusion in duos was 0.999999157188 and the cumulative power of exclusion in trios was 0.999999999859 in the Han group while the cumulative power of exclusion in duos (CPEduo) was 0.999 998 848 26 and cumulative power of exclusion in trios (CPEtrio) was 0.999 999 999 79 in the Mongolia group.And good internal consistency was found between the two investigated groups and the Sichuan Han,Hui,Tibetan and Uygur according to available reference data. | Xiang Sheng Yali Wang Jiashuo Zhang Liqin Chen Yuan Lin Zhenmin Zhao Chengtao Li Suhua Zhang | 2018 | Forensic Sciences Research2018，3，2： | 4 |
| 8 | Degradation of poly(butylene adipate-co-terephthalate) by Stenotrophomonas sp. YCJ1 isolated from farmland soil显示文摘In recent years, poly(butylene adipate-co-terephthalate)(PBAT) has been widely used. However, PBAT-degrading bacteria have rarely been reported. PBAT-degrading bacteria were isolated from farmland soil and identified. The effects of growth factors on the degradation of PBAT and the lipase activity of PBAT-degrading bacteria were assessed. The degradation mechanism was analyzed using scanning electron microscopy, attenuated total reflection Fourier transform infrared spectroscopy, proton nuclear magnetic resonance, Xray diffraction, and liquid chromatography-mass spectrometry. The results showed that Stenotrophomonas sp. YCJ1 had a significant degrading effect on PBAT. Under certain conditions, the strain could secrete 10.53 U/m L of lipase activity and degrade 10.14 wt.% of PBAT films. The strain secreted lipase to catalyze the degradation of the ester bonds in PBAT, resulting in the production of degradation products such as terephthalic acid, 1,4-butanediol, and adipic acid. Furthermore, the degradation products could participate in the metabolism of YCJ1 as carbon sources to facilitate complete degradation of PBAT, indicating that the strain has potential value for the bioremediation of PBAT in the environment. | Hao Jia Min Zhang Yunxuan Weng Yao Zhao Chengtao Li Aqsa Kanwal | 2021 | Journal of Environmental Sciences2021，33，5： | 4 |
| 9 | Validation of the DNATyper^(TM)15 PCR Genotyping System for Forensic Application显示文摘We describe the optimization and validation of the DNATyper^(TM)15 multiplex polymerase chain reaction(PCR)genotyping system for autosomal short tandem repeat(STR)amplification at 14 autosomal loci(D6S1043,D21S11,D7S820,CSF1PO,D2S1338,D3S1358,D13S317,D8S1179,D16S539,Penta E,D5S818,vWA,D18S51,and FGA)and amelogenin,a sex‑determining locus.Several DNATyper^(TM)15 assay variables were optimized,including hot start Taq polymerase concentration,Taq polymerase activation time,magnesium concentration,primer concentration,annealing temperature,reaction volume,and cycle number.The performance of the assay was validated with respect to species specificity,sensitivity to template concentration,stability,accuracy,influence of the DNA extraction methods,and the ability to genotype the mixture samples.The performance of the DNATyper^(TM)15 system on casework samples was compared with that of two widely used STR amplification kits,Identifiler^(TM)(Applied Biosystems,Carlsbad,CA,USA)and PowerPlex 16®(Promega,Madison,WI,USA).The conditions for PCR‑based DNATyper^(TM)15 genotyping were optimized.Contamination from forensically relevant nonhuman DNA was not found to impact genotyping results,and full profiles were generated for all the reactions containing≥0.125 ng of DNA template.No significant difference in performance was observed even after the DNATyper^(TM)15 assay components were subjected to 20 freeze‑thaw cycles.The performances of DNATyper^(TM)15,Identifiler^(TM),and PowerPlex 16®were comparable in terms of sensitivity and the ability to genotype the mixed samples and case‑type samples,with the assays giving the same genotyping results for all the shared loci.The DNA extraction methods did not affect the performance of any of the systems.Our results demonstrate that the DNATyper^(TM)15 system is suitable for genotyping in both forensic DNA database work and case‑type samples. | Jian Ye Chengtao Jiang Xingchun Zhao Le Wang Caixia Li Anquan Ji Li Yuan Jing Sun Shuaifeng Chen | 2015 | Journal of Forensic Science and Medicine2015，1，1： | 3 |
| 10 | Simultaneous determination of ivabradine and N-desmethylivabradine in human plasma and urine using a LC-MS/MS method: application to a pharmacokinetic study显示文摘A sensitive and specific liquid-chromatography tandem mass spectrometry(LC-MS/MS)assay has been developed and validated for the simultaneous quantification of ivabradine and its active metabolite N-desmethylivabradine in human plasma and urine.The assay employed a single liquid–liquid extraction of the analytes from plasma and urine samples,and diazepam was used as internal standard(IS).The chromatographic separation was achieved on a Diamonsil C18 column(150 mm4.6 mm,5 mm,Dikma)using a mixture of methanol and aqueous 5 mM ammonium acetate buffer containing 0.2%formic acid(80:20,v/v)as mobile phase.The assay for ivabradine and N-desmethylivabradine in plasma showed good linearity(r≥0.99)over the ranges 0.1013–101.3 ng/mL and 0.085–25.5 ng/mL,respectively.The assay for ivabradine and N-desmethylivabradine in urine showed good linearity(r≥0.99)over the ranges 10.13–6078 ng/mL and 8.5–850 ng/mL,respectively.The intra-and inter-day accuracy and precision values were found to be within the assay variability limits(RSD<15%)in accordance with FDA guidelines.The methods were successfully used for evaluating the pharmacokinetic properties of ivabradine and N-desmethylivabradine in human plasma and urine in Chinese healthy volunteers. | Chengtao Lu Yanyan Jia Jing Yang Xin Jin Ying Songa Wenxing Liu Yi Ding Xiaoli Sun Aidong Wen | 2012 | Acta Pharmaceutica Sinica B2012，2，2： | 3 |
| 11 | Double Vagueness: Uncertainty in Multi-scale Fuzzy Assignment of Duneness显示文摘In the automation of identification of landscape fe atures the vagueness arises from the fact that the attributes and parameters tha t make up a landscape vary over space and scale. In most of existing studies, t hese two kinds of vagueness are studied separately. This paper investigates thei r combination in identification of coast landscape units. Fuzzy set theory is us ed to describe the vagueness of geomorphic features due to the continuity in spa ce. The vagueness resulted from the scale of measurement is evaluated by statist ic indicators. The differences of fuzzy objects derived from data at differing r esolutions (in size from 3×3 cells to 25×25 cells) are studied in order to exa mine these higher-order uncertainties. | CHENGTao PeteFisher LIZhilin | 2004 | Geo-Spatial Information Science2004，7，1： | 3 |
| 12 | Irreducible Z+-modules of near-group fusion ring K(Z3, 3)显示文摘 | Chengtao YUAN Ruju ZHAO Libin LI | 2018 | Frontiers of Mathematics in China2018，13，4： | 3 |
| 13 | Functional difference between Sinorhizobium meliloti NifA and Enterobacter cloacae NifA显示文摘The nifA gene is an important regulatory gene and its product, NifA protein, regulates the expression of many nif genes involved in the nitrogen fixation process. We introduced multiple copies of the constitutively expressed Sinorhizobium meliloti (Sm) or Enterobacter cloacae (Ec) nifA gene into both the nifA mutant strain SmY and the wild-type strain Sm1021. Root nodules produced by SmY containing a constitutively expressed Sm nifA gene were capable of fixing nitrogen, while nodules produced by SmY containing the Ec nifA gene remained unable to fix nitrogen, as is the case for SmY itself. However, transfer of an additional Sm nifA gene into Sm1021 improved the nitrogen-fixing efficiency of root nodules to a greater extent than that observed upon transfer of the Ec nifA gene into Sm1021. Comparative analysis of amino acid sequences between Sm NifA and Ec NifA showed that the N-terminal domain was the least similar, but this domain is indispensable for complementation of the Fix? phenotype of SmY by Sm NifA. We conclude that more than one domain is involved in determining functional differences between Sm NifA and Ec NifA. | YANG Chengtao YU Guanqiao SHEN Shanjiong(San Chiun Shen) ZHU Jiabi | 2004 | Science China(Life Sciences)2004，47，1： | 2 |
| 14 | Fluid Catalytic Cracking Feed Hydrotreatment and its Impact on Distribution of Sulfur and Nitrogen Compounds in FCC Diesel显示文摘The sulfides and nitrogen compounds in FCC diesel were analyzed by gas chromatography equipped with a pulsed flame photometric detector(GC-PFPD) and gas chromatography coupled with nitrogen chemiluminescence detection(GC-NCD). And the variation of sulfides and nitrogen compounds in FCC diesel produced from gas oil feed hydrotreated at different temperatures was investigated. The test results showed that two main types of sulfur compounds, i.e. benzothiophenes(BTs) and dibenzothiophenes(DBTs) were found in diesel. Nitrogen compounds are mainly composed of non-basic nitrogen compounds, and indoles and carbazoles account for about 98% of the total nitrogen contents. The sulfides in FCC diesel obtained from hydrotreated feed are mainly BTs with a small amount of 4-MDBT and 4,6-DMDBT. With the increase in FCC feed hydrotreating temperature, indoles content in FCC diesel increases, while carbazoles content decreases. | Bai Rui Chai Yongming Zhang Chengtao Liu Chenguang | 2015 | China Petroleum Processing & Petrochemical Technology2015，17，1： | 2 |
| 15 | Temporal-spatial Distribution and Short-range Prediction Indicators of Hail Weather in East Central Haixi Prefecture of Qinghai Province显示文摘[Objective] The study aimed to discuss the temporal-spatial distribution and short-range prediction indicators of hail weather in east central Haixi Prefecture of Qinghai Province. [Method] Using hail data of six stations in east central Haixi Prefecture from 1960 to 2010, the temporal and spatial distribution of hail weather was analyzed firstly. Afterwards, based on the high-altitude factual data of 30 case studies of hail during 2006-2010, its high-altitude and ground weather situation and physical quantity field were studied to summarize short-term circulation pattern and short-range prediction characteristics of hail weather. [Result] In east central Haixi, hail appeared from April to September, and it was most frequently from May to August. Meanwhile, hail was frequent from 14:00 to 20:00. Among the six stations, hail was most frequent in Tianjun but least frequent in Wulan. Moreover, hail disaster mainly occurred in Wulan and Tianjun. In addition, there were three types of circulation pattern of hail weather at 500 hPa. Hail mainly occurred under the effect of northwest airflow, and it had shortwave trough, cold center or trough, jet stream core or one of the three. Hail appeared frequently under the situation of upper-level divergence and low-level convergence, and abundant water vapor and water vapor flux convergence at low levels were important conditions for hailing. [Conclusion] The research could provide scientific references for improving the accuracy of hail forecast. | Xiuping Cheng Chengtao Shan Gasang Pei Na Wang | 2013 | Meteorological and Environmental Research2013，4，4： | 2 |
| 16 | A Wavelet-Based Method to Predict Muscle Forces From Surface Electromyography Signals in Weightlifting显示文摘 | Gaofeng Wei Feng Tian Gang Tang Chengtao Wang | 2012 | Journal of Bionic Engineering2012，9，1： | 2 |
| 17 | Detecting genetic hypermutability of gastrointestinal tumor by using a forensic STR kit显示文摘Growing evidence suggests that somatic hypermutational status and programmed cell death-1 overexpression are potential predictive biomarkers indicating treatment benefits from immunotherapy using immune checkpoint inhibitors.However,biomarker-matched trials are still limited,and many of the genomic alterations remain difficult to target.To isolate the potential somatic hypermutational tumor from microsatellite instability low/microsatellite stability(MSI-L/MSS)cases,we employed two commercial kits to determine MSI and forensic short tandem repeat(STR)alternations in 250 gastrointestinal(GI)tumors.Three types of forensic STR alternations,namely,allelic loss,Aadd,and Anew,were identified.62.4%(156/250)of the patients with GI exhibited STR alternation,including 100%(15/15)and 60%(141/235)of the microsatellite high instability and MSI-L/MSS cases,respectively.30%(75/250)of the patients exhibited STR instability with more than 26.32%(26.32%–84.21%)STR alternation.The cutoff with 26.32%of the STR alternations covered all 15 MSI cases and suggested that it might be a potential threshold.Given the similar mechanism of the mutations of MSI and forensic STR,the widely used forensic identifier STR kit might provide potential usage for identifying hypermutational status in GI cancers. | Anqi Chen Suhua Zhang Jixi Li Chaoneng Ji Jinzhong Chen Chengtao Li | 2020 | Frontiers of Medicine2020，14，1： | 2 |
| 18 | Genomic Insight into the Antimicrobial Resistance of Streptococcus Suis-Six Countries,2011-2019显示文摘Summary What is already known on this topic?Streptococcus suis(S.suis)is a zoonotic pathogen causing disease in humans and animals,and the emergence of its increased resistance to antimicrobial agents has become a significant challenge in many countries. | Lichao Ma Wanjiang Zhang Jingyun Ma Qingpo Cui Chaoyang Zhang Peng Zhang Chengtao Sun Huarun Sun Yao Zhu Shaolin Wang Shuangyang Ding Gongzheng Hu Zhangqi Shen | 2021 | China CDC weekly2021，3，47： | 2 |
| 19 | Determination of ifenprodil by LC–MS/MS and its application to a pharmacokinetic study in healthy Chinese volunteers显示文摘This paper reports the development and validation of an assay for ifenprodil based on liquid chromatography–tandem mass spectrometry(LC–MS/MS)and its application to a pharmacokinetic study involving single and multiple intravenous infusions to healthy Chinese volunteers.After sample preparation of plasma by liquid–liquid extraction with ethyl acetate,the analyte and internal standard,urapidil,were separated by reversed phase chromatography in a run time of 4 min and detected by positive ion electrospray ionization followed by multiple reaction monitoring of the precursor-to-product ion transitions at m/z 326.2-308.1 for ifenprodil and m/z 388.4-205.3 for IS.The assay was linear in the concentration range 0.2–50.0 ng/mL with recovery 476.4%.In the pharmacokinetic study of single intravenous infusions of 5,10 and 15 mg ifenprodil,peak plasma concentrations and areas under the plasma concentration–time curve were both linearly related to dose.In the pharmacokinetic study of multiple once daily intravenous infusions of 10 mg ifenprodil for 7 days,pharmacokinetic parameters were similar to those after the single dose showing that ifenprodil does not accumulate on repeated administration. | Jing Yang Chengtao Lu Wei Song Jiankang Li Yi Ding Yanrong Zhu Jinyi Cao Likun Ding Yanyan Jia Aidong Wen | 2013 | Acta Pharmaceutica Sinica B2013，3，3： | 2 |
| 20 | Research of optical and structural properties in Cu/Ti multilayer films 显示文摘 | Yang Chengtao Zhang Shuren Luo Jiahui | 2005 | Vacuum2005，80，4： | 1 |
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