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| 1 | Shape-free finite element method:The plane hybrid stress-function (HS-F) element method for anisotropic materials显示文摘The sensitivity problem to mesh distortion and the low accuracy problem of the stress solutions are two inherent difficulties in the finite element method.By applying the fundamental analytical solutions (in global Cartesian coordinates) to the Airy stress function of the anisotropic materials,8-and 12-node plane quadrilateral hybrid stress-function (HS-F) elements are successfully developed based on the principle of the minimum complementary energy.Numerical results show that the present new elements exhibit much better and more robust performance in both displacement and stress solutions than those obtained from other models.They can still perform very well even when the element shapes degenerate into a triangle and a concave quadrangle.It is also demonstrated that the proposed construction procedure is an effective way for developing shape-free finite element models which can completely overcome the sensitivity problem to mesh distortion and can produce highly accurate stress solutions. | CEN Song FU XiangRong ZHOU GuoHua ZHOU MingJue LI ChenFeng | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，4： | 7 |
| 2 | A simple approach for bubble modelling from multiphase fluid simulation显示文摘This article presents a novel and flexible bubble modelling technique for multi-fluid simulations using a volume fraction representation. By combining the volume fraction data obtained from a primary multi-fluid simulation with simple and efficient secondary bubble simulation, a range of real-world bubble phenomena are captured with a high degree of physical realism, including large bubble deformation,sub-cell bubble motion, bubble stacking over the liquid surface, bubble volume change, dissolving of bubbles,etc. Without any change in the primary multi-fluid simulator, our bubble modelling approach is applicable to any multi-fluid simulator based on the volume fraction representation. | Bo Ren Yuntao Jiang Chenfeng Li Ming C.Lin | 2015 | Computational Visual Media2015，1，2： | 3 |
| 3 | Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury显示文摘Compelling evidence has revealed that biased activation of G protein-coupled receptor(GPCR)signaling,including angiotensin II(AngII)receptor type 1(AT1)signaling,plays pivotal roles in vascular homeostasis and injury,but whether a clinically relevant endogenous biased antagonism of AT1 signaling exists under physiological and pathophysiological conditions has not been clearly elucidated.Here,we show that an extracellular matrix protein,cartilage oligomeric matrix protein(COMP),acts as an endogenous allosteric biased modulator of the AT1 receptor and its deficiency is clinically associated with abdominal aortic aneurysm(AAA)development.COMP directly interacts with the extracellular N-terminus of the AT1 via its EGF domain and inhibits AT1-β-arrestin-2 signaling,but not Gq or Gi signaling,in a selective manner through allosteric regulation of AT1 intracellular conformational states.COMP deficiency results in activation of AT1a-β-arrestin-2 signaling and subsequent exclusive AAA formation in response to AngII infusion.AAAs in COMP–/–or ApoE–/–mice are rescued by AT1a orβ-arrestin-2 deficiency,or the application of a peptidomimetic mimicking the AT1-binding motif of COMP.Explorations of the endogenous biased antagonism of AT1 receptor or other GPCRs may reveal novel therapeutic strategies for cardiovascular diseases. | Yi Fu Yaqian Huang Zhao Yang Yufei Chen Jingang Zheng Chenfeng Mao Zhiqing Li Zhixin Liu Bing Yu Tuoyi Li Meili Wang Chanjuan Xu Yiwei Zhou Guizhen Zhao Yiting Jia Wei Guo Xin Jia Tao Zhang Li Li Ziyi Liu Shengchao Guo Mingliang Ma Heng Zhang Bo Liu Junbao Du Wengong Wang Chaoshu Tang Pei Gao Qingbo Xu Xian Wang Jianfeng Liu Jinpeng Sun Wei Kong | 2021 | Cell Research2021，31，7： | 2 |
| 4 | Visual Simulation of Multiple Fluids in Computer Graphics: A State-of-the-Art Report显示文摘在多重液体之间的各种各样的相互作用的现实主义的动画,可能经历阶段变化,是在计算机图形的一项挑战性的任务。多相的多液体现象的视觉范围盖住复杂纠缠的表面结构和富有的颜色变化,它能极大地在图形应用提高视觉效果。描述如此的现象要求更复杂的模型处理包含相互作用,动力学和多重阶段的空间分发的计算的挑战,它经常被包含并且难获得即时性能。最近,算法的一个多样的集合被介绍了基于管理实现复杂多液体现象物理法律和新奇 discretization 方法到当保证时,加速全面计算数字稳定性。由在多重液体的宽广题目通过最近的研究的目标现象排序,这份最先进的报告在计算机图形在多液体模拟上总结最近的进展。 | Bo Ren Xu-Yun Yang Ming C. Lin Nils Thuerey Matthias Teschner Chenfeng Li | 2018 | Journal of Computer Science & Technology2018，33，3： | 2 |
| 5 | Preparation, thermal stability and flame-retardant properties of halogen free polypropylene composites 显示文摘 | Li Yiluen Kuan Chenfeng Hsu Shuwei | 2012 | High Performance Polymers2012，24，6： | 1 |
| 6 | Finite element analysis for inclined wellbore stability of transversely iso-tropic rock with HMCD coupling based on weak plane strength criterion显示文摘The finite element analysis(FEA) technology by hydraulic-mechanical-chemical-damage(HMCD) coupling is proposed in this paper for inclined wellbore stability analysis of water-sensitive and laminated rock, developed basing on the recently established FEA technology for transversely isotropic rock with hydraulic-mechanical-damage(HMD) coupling. The chemical activity of the drilling fluid is considered as phenomenological hydration behavior, the moisture content and parameters of rock considering hydration could be determined with time. The finite element(FE) solutions of numerical wellbore model considering the chemical activity of drilling fluid, damage tensor calculation and weak plane strength criterion for transversely isotropic rock are developed for researching the wellbore failure characteristics and computing the time-dependent collapse and fracture pressure of laminated rock as shale reservoirs. A three-dimensional FE model and elastic solid deformation and seepage flow coupled equations are developed, and the damage tensor calculation technology for transversely isotropic rock are realized by introducing effect of the hydration and the stress state under the current load. The proposed method utilizing weak plane strength criterion fully reflects the strength parameters in rock matrix and weak plane. To the end, an effective and reliable numerically three-step FEA strategy is well established for wellbore stability analysis. Numerical examples are given to show that the proposed method can establish efficient and applicable FE model and be suitable for analyzing the timedependsolutions of pore pressure and stresses, and the evolution region considering the hydration surrounding wellbore,furthermore to compute the collapse cycling time and the safe mud weight for collapse and fracture pressure of transversely isotropic rock. | WANG YongLiang ZHUANG Zhuo LIU ZhanLi YANG HengLin LI ChenFeng | 2017 | Science China(Technological Sciences)2017，60，4： | 1 |
| 7 | Analysis of a mutualism model with stochastic perturbations显示文摘 | Mei Li Hongjun Gao Chenfeng Sun Yuezheng Gong | 2015 | International Journal of Biomathematics2015，8，6： | 1 |
| 8 | Application of Langlois' reagent(NaSO_(2)CF_(3)) in C–H functionalisation显示文摘The process of selectively introducing a CF_(3) group into an organic molecule using inexpensive, stable, and solid sodium trifluoromethanesulfinate has rapidly advanced in recent years to become an eco-friendly method used by organic chemists to synthesize various natural and bioactive molecules. This review focuses on advances made within the last five years regarding C-H functionalisation, namely thermochemical C(sp^(2))-H (thio)trifluoromethylations, photochemical C(sp^(2))-H trifluoromethylations, and electrochemical C(sp^(2))-H trifluoromethylations, using Langlois’ reagent (NaSO_(2)CF_(3)). | Jiabin Shen Jun Xu Lei He Chenfeng Liang Wanmei Li | 2022 | Chinese Chemical Letters2022，33，3： | 1 |
| 9 | Fisheye video correction 显示文摘 | Wei Jin Li Chenfeng Hu Shimin | 2012 | IEEE Transactions on Visualization and Computer Graphics2012，18，10： | 1 |
| 10 | Fisheye video correc- tion 显示文摘 | Wei Jin Li Chenfeng Hu Shimin | 2012 | IEEE Transactions on Visualization and Computer Graphics2012，18，10： | 1 |
| 11 | Isolation and identification of antioxidative peptides from porcine collagen hydrolysate by consecutive chromatography and electrospray ionization-mass spectrometry 显示文摘 | Li Bo ChenFeng | 2007 | Food Chemistry2007，102，： | 1 |
| 12 | Fisheye video correction显示文摘 | Wei Jin Li Chenfeng Hu Shimin Ralph R M Tai C L | | 0，，10： | 1 |
| 13 | Periodic signal extraction of GNSS height time series based on adaptive singular spectrum analysis显示文摘Singular spectrum analysis is widely used in geodetic time series analysis.However,when extracting time-varying periodic signals from a large number of Global Navigation Satellite System(GNSS)time series,the selection of appropriate embedding window size and principal components makes this method cumbersome and inefficient.To improve the efficiency and accuracy of singular spectrum analysis,this paper proposes an adaptive singular spectrum analysis method by combining spectrum analysis with a new trace matrix.The running time and correlation analysis indicate that the proposed method can adaptively set the embedding window size to extract the time-varying periodic signals from GNSS time series,and the extraction efficiency of a single time series is six times that of singular spectrum analysis.The method is also accurate and more suitable for time-varying periodic signal analysis of global GNSS sites. | Chenfeng Li Peibing Yang Tengxu Zhang Jiachun Guo | 2024 | Geodesy and Geodynamics2024，15，1： | 0 |
| 14 | mTORC1 induces plasma membrane depolarization and promotes preosteoblast senescence by regulating the sodium channel Scn1a显示文摘Senescence impairs preosteoblast expansion and differentiation into functional osteoblasts,blunts their responses to bone formation-stimulating factors and stimulates their secretion of osteoclast-activating factors.Due to these adverse effects,preosteoblast senescence is a crucial target for the treatment of age-related bone loss;however,the underlying mechanism remains unclear.We found that mTORC1 accelerated preosteoblast senescence in vitro and in a mouse model.Mechanistically,mTORC1 induced a change in the membrane potential from polarization to depolarization,thus promoting cell senescence by increasing Ca^(2+)influx and activating downstream NFAT/ATF3/p53 signaling.We further identified the sodium channel Scn1a as a mediator of membrane depolarization in senescent preosteoblasts.Scn1a expression was found to be positively regulated by mTORC1 upstream of C/EBPα,whereas its permeability to Na^(+)was found to be gated by protein kinase A(PKA)-induced phosphorylation.Prosenescent stresses increased the permeability of Scn1a to Na^(+)by suppressing PKA activity and induced depolarization in preosteoblasts.Together,our findings identify a novel pathway involving mTORC1,Scn1a expression and gating,plasma membrane depolarization,increased Ca^(2+)influx and NFAT/ATF3/p53 signaling in the regulation of preosteoblast senescence.Pharmaceutical studies of the related pathways and agents might lead to novel potential treatments for agerelated bone loss. | Ajuan Chen Jian Jin Shasha Cheng Zezheng Liu Cheng Yang Qingjing Chen Wenquan Liang Kai Li Dawei Kang Zhicong Ouyang Chenfeng Yao Xiaochun Bai Qingchu Li Dadi Jin Bin Huang | 2022 | Bone Research2022，10，2： | 0 |
| 15 | Welding molecules into polymeric chains in one fell swoop显示文摘Molecular components that are not covalently linked buttopologically interlocked represent a family of moleculesnamed mechanically interlocked molecules (MIMs) [1].One archetype of MIMs is catenane (the Latin "catena"means "chain"), which is formed between two ([2]cate-nane, Fig. la) or more ([n]catenane) mechanically inter-locked rings. Similar to their macroscopic counterpart, i.e., interlocked metal chains, these molecular ring com-ponents can move and deform (Fig. lb) in response toexternal stimuli. | Longyu Li Chenfeng Ke | 2018 | Science China Materials2018，61，7： | 0 |
| 16 | Rapid alkenylation of quinoxalin-2(1H)-ones enabled by the sequential Mannich-type reaction and solar photocatalysis显示文摘Herein,a rapid alkenylation of quinoxalin-2(1H)-ones enabled by a combination of Mannich-type reaction and solar photocatalysis is demonstrated.A wide range of functional groups are compatible,affording the corresponding products in moderate-to-good yields.Control experiments illustrate that the in situ generated^(1)O_(2)plays a central role in this reaction.This green and efficient strategy provides a practical solution for the synthesis of potentially bioactive compounds that containing a 3,4-dihydroquinoxalin-2(1H)-one structure. | Lin Huang Jun Xu Lei He Chenfeng Liang Yani Ouyang Yongping Yu Wanmei Li Pengfei Zhang | 2021 | Chinese Chemical Letters2021，32，11： | 0 |
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