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| 1 | An overview of clinical andexperimental treatment modalities for port wine stains显示文摘 | ChenJK Ghasri P Aquilar G | 2012 | JAm Acad Dermatol2012，67，2： | 1 |
| 2 | Failureanalysisofagraphite/epoxylaminatesubjectedtocombinedthermalandmechanicalloading显示文摘 | ChenJK SunCT ChangCI | 1985 | JCompositeMaterials1985，19，： | 1 |
| 3 | Cardioprotectiveeffectofresveratrolanaturalantioxidantderivedfromgrapes显示文摘 | HungLM ChenJK HuangSS etal | 2000 | Cardio-vascRes2000，47，3： | 1 |
| 4 | The USe of radioactive zinc ox?ide nanoparticles in determination of their tissue concentrations fol?lowing intravenous administration in mice显示文摘 | ChenJK Shih MH PeriJ J | 2010 | Analyst2010，135，7： | 1 |
| 5 | Modellingofultrashortlaserablationofgoldfilmsinvacuum显示文摘 | ChenJK BeraunJE | 2003 | JournalofOpticsA :PureandAppliedOptics2003，5，3： | 1 |
| 6 | Ultrafastsolid-liquid-vaporphasechangeofagoldfilminducedbypico-to-femtosecondlasers显示文摘 | HuangJ ZhangY ChenJK | 2009 | AppliedPhysicsA2009，95，3： | 1 |
| 7 | Ultrafastphasechangeduringfemtosecondlaserinteractionwithgoldfilms:effectoffilmthickness显示文摘 | HuangJ ZhangY ChenJK | 2010 | NumericalHeatTransfer PartA :Applications2010，57，12： | 1 |
| 8 | Oxidativestress-inducedat-tenuationofthrombospondin-1expressioninprimaryratastro-cytes显示文摘 | ChenJK ZhanYJ YangCS etal | 2011 | JCellBiochem2011，112，1： | 1 |
| 9 | Aliteraturereviewonplantcompetition显示文摘 | LiB ChenJK WatkinsonA R | 1998 | ChineseBullBot1998，15，4： | 1 |
| 10 | Effect of fluoroalkyl substituents on the reactions of alkylchlorosilanes with mold surfaces for nanoimprint lithography显示文摘 | CHENJK KOFH HSIEHKF etal | 2004 | J Vac Sci Technol B2004，22，6： | 1 |
| 11 | Resveratrol,a red wine antioxidant,possesses an insulin-like effect in streptozotocin-induced diabetic rats显示文摘 | SuHc HungLM ChenJK | 2006 | Am J Physiol Endocrinol Metab2006，290，： | 1 |
| 12 | YC-1 rescues cancer cachexia by affecting lipolysis and adipogenesis显示文摘 | ChungTH Yen-Ping KuoM ChenJK | 2011 | Int J Cancer2011，129，9： | 1 |
| 13 | Numericalstudyofultrashortlaserpulseinteractionswithmetalfilms显示文摘 | ChenJK BeraunJE | 2001 | NumericalHeatTransferPartA :Applications2001，40，1： | 1 |
| 14 | Theapplicationoftheconceptandmethodofpopulationtoplanttaxonomy显示文摘 | ChenJK(陈家宽) WangHQ(王徽勤) | 1986 | 武汉植物学研究1986，4，4： | 1 |
| 15 | Network analyses of differen?tially expressed proteins in amniotic fluid supernatant associated with abnormal human karyotypes显示文摘 | Wang TH Chao AS ChenJK | 2009 | Fertil Steril2009，92，1： | 1 |
| 16 | Theroleofelectron-phononcouplinginultrafastlaserheating显示文摘 | ChenJK Latham W P BeraunJE | 2005 | JournalofLaserApplications2005，17，1： | 1 |
| 17 | Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule-specific knockout mouse models显示文摘 | WeiQ DongG ChenJK | 2013 | Kidney Int2013，84，1： | 1 |
| 18 | Astudyoflaser/compositematerialinteractions显示文摘 | ChenJK PereaA AllahdadiFA | 1995 | CompositesScienceandTechnology1995，54，1： | 1 |
| 19 | Identification of amino acid residues of abrin-a A chain is essential for catalysis and reassociation with abrin-a B chain by site-directed mutagenesis显示文摘 | ChenJK HungCH LiawYC etal | 1997 | Protein Eng1997，10，7： | 1 |
| 20 | The molecular mechanisms of hazardous metals for carcinogenesis显示文摘The available experimental and epidemiological data have shown that nickel (Ni) and cadmium (Dd) and their compounds are carcinogenic to experimental animals and human.These two metals have been classified as human carcinogens bythe International Agency for Research on Cancer (IARC).However,Their underlying molecular mechanisms remain unknown.The objective of this research was to investigate the molecular mechanisms responsible for Ni and Cd carcinogenesis through epidemiological study in human exposure,transformation expreiments in human epithelial cells (16HBE) and BALB/c-3T3 cell lines in vitro,DNA damage detections (comet,DNA-protein crosslinks) as well as telomerase activity and apoptosis assay,and analysis of oncogens,tumor suppressor genes and their mutation (including genomic instability,k-ras,p15,p16,p53,FHIT) in transformed cell lines or tumor cells/tissue.Furthermore,we also detected and analyses the methylation,related novel genes and encoded protein in Cd transformed cells.The results and conclusion are as follows:(1)There is significant relationship between some hazardous metals and lung cancer (OR=8.76),especially for nickel(OR=11.25).(2)Ni and Cd and their compounds could induce malignant transformation in mammalian cell lines and human epithelial cells,and induce tumorigenesis in nude mice.(3)There is obvious DNA damage during cell transformation and tumorigenesis induced by Ni.(4) Significant genomic instability has been shown during cell transformation and tumorigenesis induced by Ni.(5)Detection of k-ras,p15,p16 genes in point mutation have demonstrated no changes during cell transformation and tumorigenesis induced by hazardous medals,suggesting that gene mutation is not the main way to metal carcinogenesis.(6)There are some aberrant DNA methylation in Cdtransformed cell lines.(7)We found two novel Cd-responsive proto-oncogenes and their encoded proteins in Cd-transformed cell lines. | ChenJK LeiYX | 2002 | 中国药理学与毒理学杂志2002，16，6： | 0 |
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