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| 1 | Synthesis and Properties of Functionalized Schiff Bases of 5α,10α-Di(4-hydroxylphenyl)calix[4]pyrrole and 5α,15β-Di(4-hydroxylphenyl)calix|4] pyrrole显示文摘 | HAN Ying SUN Juanjuan WANG Genliang YAN Chaoguo | 2014 | Chemical Research in Chinese Universities2014，30，6： | 2 |
| 2 | Pillar[5]arene-based [3]rotaxanes: Convenient construction via multicomponent reaction and pH responsive self-assembly in water显示文摘Four pillar[5]arene based[3]rotaxanes(1-4)involving two 1,4-diethoxypillar[5]arene(DEP5)rings and a dumbbell-shaped component were successfully synthesized.The dumbbell-shape molecules contain one longer bridge,two triazole sites and two multicomponent stoppers.After threading DEP5 rings with linear guests(G1-G4)which contain two benzaldehyde units,the base catalyzed three-component reaction of dimedone,malononitrile and benzaldehyde was performed to construct the stoppers and connected the pseudorotaxanes with stoppers to generate 1-4.The structures of[3]rotaxanes and their self-assembly behaviors were characterized by 1 H NMR,13C NMR,NOESY,HR-ESI-MS,DLS and TEM technologies.We hope that pillar[5]arene based[3]rotaxanes may have potential applications in drug delivery systems and molecular devices. | Junmei Ye Runmiao Zhan Wenjuan Yang Ying Han Hao Guo Ju Xie Chaoguo Yan Yong Yao | 2020 | Chinese Chemical Letters2020，31，6： | 1 |
| 3 | Synthesis and Crystal Structure ofp-tert-Butylcalix[4]arene 1,3-Distal and Monosubstituted Semicarbazones and Thiosemicarbazones显示文摘 | LIU Zhenming LIU Dongmei WANG Jinxiang SUN Jing YAN Chaoguo | 2014 | Chemical Research in Chinese Universities2014，30，3： | 1 |
| 4 | Selective Synthesis of 1,2-Diarylpyrrolo[3,4-b]pyridine-5,7- diones via Cyclization Reaction of β-Enamino Imides with Cinnamaldehydes显示文摘 | Yanhong Jiang Chaoguo Yan | 2016 | Chinese Journal of Chemistry2016，34，12： | 0 |
| 5 | 1,3-Indanedione:An versatile building block显示文摘Indanone-containing compounds are very important components of various natural products,chemical drugs,agrochemicals and functionalized material fields.1,3-Indanedione is a typical cyclic 1,3-dicarbonyl compound with three contiguous reactive electrophilic and nucleophilic sites.The easily prepared 2-arylidene-1,3-indanediones are activeα,β-unsaturated carbonyl compounds and could act as 1,3-dipolarophile,1,4-dienophile and 1-oxa-1,3-diene,etc.On the other hand,the homodimer(bindone)and cyclotrimer(truxenone)derived from basecatalyzed self-condensation of 1,3-indanedione are also reactive carbonyl compounds.Therefore,1,3-indanedione and its derivatives can be employed as key substrates in various domino and multicomponent reactions.In this review,we summarized the recent progress on the domino and multicomponent reactions of 1,3-indanedione,especially on our achievements on the synthetic applications for the complex indanone-containing carbocyclic and heterocyclic compounds. | Chaoguo Yan | 2023 | Green Synthesis and Catalysis2023，4，2： | 0 |
| 6 | Convenient Synthesis of Spiro[benzo[d]pyrrolo[2,1-b]thiazole- 3,2'-indenes] Derivatives via Three-Component Reaction显示文摘 | Guoliang Shen Jing Sun Chaoguo Yan | 2016 | Chinese Journal of Chemistry2016，34，4： | 0 |
| 7 | A novel four-component reaction involving ring-opening/recyclization of 1,3-thiazolidinedione显示文摘The multicomponent reactions of 1,3-thiazolidinedione, malononitrile, aromatic aldehydes and α-phenylethylamine or β-phenylethylamine in acetonitrile at room temperature produce dihydrothiophene ureidoformamide derivatives in moderate yields through a domino ring-opening/recyclization reaction of 1,3-thiazolidinedione. On treatment with DDQ, dihydrothiophenes are dehydrogenated to convert efficiently to thiophenes in the mild condition. | SUN Jing, XIA ErYan, ZHANG LiLi & YAN ChaoGuo College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China | 2010 | Science China Chemistry2010，53，4： | 0 |
| 8 | Efficient Synthesis of Spiro[furan-3,3'-indoline] Derivatives via Reactions of Pyridinium Salts with Isatinylidene Acetoacetates显示文摘为 functionalized spiro 的一个有效合成过程[furan-3,3-indoline ] 衍生物被 N-phenacylpyridinium 溴化物或 N-ethoxycarbonylmethylenepyridinium 溴化物的牙齿反应成功地在乙醇面对 triethylamine 与 isatinylidene acetoacetate 开发在房间温度。机制包括了顺序的迈克尔增加在里面 situ 产生了 enolate 的 pyridinium ylide 和 intramolecular 替换。 | Zhenming Liu Jun Fang Chaoguo Yan | 2013 | Chinese Journal of Chemistry2013，31，8： | 0 |
| 9 | Synthesis of Dispirocyclopentyl-3,3'-bisoxindoles via Domino Cycloaddition Reactions of 4-Dimethylaminopyridinium Bromides with 3-Phenacylideneoxindoles显示文摘 | Lijuan Lu Chaoguo Yan | 2015 | Chinese Journal of Chemistry2015，33，10： | 0 |
| 10 | Diastereoselective Synthesis of Arylidene Bis(3-arylamino- acrylates) via One-pot Domino Reactions显示文摘functionalized arylidene 二度(3-arylaminoacrylates ) 被 FeCl3 高效地准备主要的胺,甲基 propiolate 和芳香的醛的催化一个壶牙齿反应。当靛红在类似的条件下面被利用时,仅仅 2-oxoindolinyl 3-arylaminoacrylates 在中等收益被获得。1H NMR 数据和单个水晶结构显示这反应有高 diastereoselectivity。 | Zhenming Liu Lili Zhang Jing Sun Chaoguo Yan | 2013 | Chinese Journal of Chemistry2013，31，4： | 0 |
| 11 | Syntheses and Crystal Structures of Functionalized Tetramethyl Resorcinarenes显示文摘 | MU Huarong ZHOU Rui SUN Jing YAN Chaoguo | 2015 | Chemical Research in Chinese Universities2015，31，6： | 0 |
| 12 | Synthesis of Functionalized 1-Benzamido-1,4-dihydropyridines via a One-Pot Two-Step Four-Component Reaction显示文摘The one-pot four-component reaction of benzohydrazide,acetylenedicarboxylate,aromatic aldehydes and malononitrile in ethanol with triethylamine as base catalyst afforded functionalized 1-benzamido-1,4-dihydropyridines in satisfactory yields.Under similar conditions,picolinohydrazide or nicotinohydrazide can also be successfully utilized in the reactions to give corresponding functionalized 1,4-dihydropyridines.1H NMR data indicated that an equilibrium of cis/trans-conformations exist in 1-benzamido-1,4-dihydropyridines. | Jing Sun Guoliang Shen Yajing Xie Chaoguo Yan | 2014 | Chinese Journal of Chemistry2014，32，11： | 0 |
| 13 | Synthesis, Crystal Structure and Copper Complex of 1,3-Alternate p-tert-Butylthiacalix[4]arene 2-picolyl Schiff Base显示文摘 | HUANG Kun LIU Kai YAN Chaoguo | 2014 | Chemical Research in Chinese Universities2014，30，2： | 0 |
| 14 | Development, Application and Prospect of Dissolving Microneedles显示文摘In recent years, as a new transdermal drug delivery method, microneedle transdermal drug delivery technology accelerates the absorption of drugs through micron pores, which has been widely used in the field of medicine and cosmetics. Dissolving microneedles have the characteristics of good biocompatibility and fast dissolution speed, which attract more and more researchers’ attention and research. In this paper, the concept, properties and preparation methods of dissolving microneedles as well as the research status of dissolving microneedles in the field of medicine and cosmetics in recent years were summarized and prospected, so as to enable researchers to have a clearer and comprehensive understanding of dissolving microneedles and prospect the application and development prospects of dissolving microneedles in the industry. | Juan YAN Chaoguo SUN Yanjing LI Yuchen CUI Dongfang SHI Suohui ZHANG | 2023 | Agricultural Biotechnology2023，12，1： | 0 |
| 15 | One-pot Two-Step Cycloaddition Reaction for Convenient Synthesis of Polycyclic Spirooxindole-fused [1,3]Oxazines显示文摘熔化的新奇 spirooxindoline [1,3 ] 哑嗪高效地与 1,2-dihydro-2-oxospiro 从 N-arylmaleimides 的一天一夜桤木的反应被综合[3H-indole-3,2 ′-[2H,9aH-pyrido [2,1-b ][1,3 ] 哑嗪] ,它与甲基 propiolate,或 dimethyl acetylenedicarboxylate 从代替的 pyridines 和靛红的三部件的反应在 situ 被产生。产品的立体化学被 1 H NMR 数据和获得的多不的混合物的单个水晶结构。 | Jing Sun Hui Gong Chaoguo Yan | 2015 | Chinese Journal of Chemistry2015，33，9： | 0 |
| 16 | Diastereoselective Synthesis of Functionalized Tetrahydropyrimidin-2-thiones via ZnCl2 Promoted One-pot Reactions显示文摘In the presence of zinc chloride,the in situ generatedβ-enamino ester from the reaction of morpholine,piperidine and pyrrolidine with methyl propiolate reacted,with aromatic aldehydes and thiourea in ethanol resulting in the functionalized tetrahydropyrimidin-2-thiones in satisfactory yields and with good diastereoselectivity.When aromatic aldehydes bearing electron-withdrawing group were used in the reaction,the 4-hydroxytetrahydropyrimidin-2-thione derivatives were obtained as the main product. | Zhenming Liu Lili Zhang Jing Sun Chaoguo Yan | 2014 | Chinese Journal of Chemistry2014，32，2： | 0 |
| 17 | A microenvironment sensitive pillar[5]arene-based fluorescent probe for cell imaging and drug delivery显示文摘Dansylamide(DNSA) is a typical ICT probe that has a favorable serum albumin sensitivity. Inspired by this, we designed a microenvironment sensitive fluorescent probe 4 C-G through introducing DNSA into pillar[5]arene. Unlike DNSA, 4 C-G displayed differentiated sensitivity to multiple proteins, which was benefit from pillar[5]arene assisted the probe to form complexes with proteins. 4 C-G could not only be applied in imaging of Hep G2, but also act as a favorable drug carrier for regorafenib(REG) encapsulation.The 4 C-G-REG complex would aggregate into high drug-loading fluorescent nanoparticles in a physiological environment(pH 7.4). Such nanoparticles exhibited p H-triggered enrichment ability, which rapidly enriched REG in the acidic environment(pH 6.0). Furthermore, the complexation between 4 C-G and REG maintained the imaging property of the probe and the excellent anticancer activity of the drug on Hep G2. | Qing Wang Jingwen Fan Xiaoyan Bian Hang Yao Xiaohui Yuan Ying Han Chaoguo Yan | 2022 | Chinese Chemical Letters2022，33，4： | 0 |
| 18 | Synthesis of Highly Stable Porous Metal-lminodiacetic Acid Gels from a Novel IDA Compound显示文摘 | Wenjing Chen Yanhong Jiang Xuesong Ding Chaoguo Yan Baohang Han | 2016 | Chinese Journal of Chemistry2016，34，6： | 0 |
| 19 | Three-Component Reaction for Construction of Spiro[indoline- 3,7'-thiazolo[3,2-a]pyridines] and Spiro[benzo[4,5]- thiazolo[3,2-a]pyridine-3,3'-indolines]显示文摘 | Fan Yang Jing Sun Chaoguo Yan | 2015 | Chinese Journal of Chemistry2015，33，12： | 0 |
| 20 | Molecular Diversity of Three-Component Reaction of β-Enamino Imide, Malononitrile and Cyclic α-Diketones显示文摘在 acetonitrile 的 -enamino imide, malononitrile 和各种各样的周期的 -diketones 的基础支持的三部件的反应显示出有趣的分子的差异。有 acenaphthylene-1,2-dione 和 ninhydrin 的反应负担得起 functionalized spiro [indene-2,4-pyrrolo [3,4-b ] pyridines ] 并且 spiro [acenaphthylene-1,4-pyrrolo [3,4-b ] pyridines ] 在好收益。phenanthrene-9,10-dione 的类似的反应导致了意外复杂 phenanthro 的形成[9,10:4,5 ] furo [2,3-c ] pyrrolo [3,4-b ] 在令人满意的收益的吡咯。 | Man Xiao Chaoguo Yan | 2017 | Chinese Journal of Chemistry2017，35，9： | 0 |
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