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| 1 | 脉冲染料激光联合外用咪喹莫特与单纯激光治疗鲜红斑痣的初步对比研究显示文摘研究目的评估脉冲染料激光(pulsed dye laser PDL)联合外用咪喹莫特治疗与单纯激光治疗鲜红斑痣的疗效。研究设计对20名亚裔鲜红斑痣受试者的结果进行评估。鲜红斑痣皮损内设置三个治疗测试区:A区用PDL+外用咪喹莫特治疗;B区单纯PDL治疗;C区单纯外用咪喹莫特软膏治疗。治疗后1、3、6和12个月进行随访,利用皮肤光谱检测仪测量血红蛋白指数。 | 苑凯华 Chang CJ Hsiao YC Mihm MC | 2011 | 中国激光医学杂志2011，20，1： | 6 |
| 2 | Protective effects of Ginkgo biloba extract on the ethanol-induced gastric ulcer in rats显示文摘AIM: To evaluate the preventive effect of Ginkgo bilobaextract (GbE) on ethanol-induced gastric mucosal injuries in rats.METHODS: Female Wistar albino rats were used for the studies. We randomly divided the rats for each study into five subgroups: normal control, experimental control, and three experimental groups. The gastric ulcers were induced by instilling 1 mL 50% ethanol into the stomach. We gaveGbE 8.75, 17.5, 26.25 mg/kg intravenously to the experimental groups respectively 30 min prior to the ulcerative challenge. We removed the stomachs 45 min later. The gastric ulcers,gastric mucus and the content of non-protein sulfhydryl groups (NP-SH), malondialdehyde (MDA), c-Jun kinase (JNK) activity in gastric mucosa were evaluated. The amount of gastric juice and its acidity were also measured. RESULTS: The findings of our study are as follows: (1)GbE pretreatment was found to provide a dose-dependent protection against the ethanol-induced gastric ulcers in rats; (2) the GbE pretreatment afforded a dose-dependent inhibition of ethanol-induced depletion of stomach wall mucus, NP-SH oontents and increase in the lipid peroxidation (increase MDA) in gastric tissue; (3) gastric ulcer induced by ethanolproduced an increase in JNK activity in gastric mucosawhich also significantly inhibited by pretreatment with GbE;and (4) GbE alone had no inhibitory effect on gastric secretionin pylorus-ligated rats.CONCLUSION: The finding of this study showed that GbE significantly inhibited the ethanol-induced gastric lesions in rats. We suggest that the preventive effect of GbE may be mediated through: (1) inhibition of lipid peroxidation;(2) preservation of gastric mucus and NP-SH; and (3)blockade of cell apoptosis. | Sheng-Hsuan Chen Yu-Chih Liang Jane CJ Chao Li-Hsueh Tsai Chun-Chao Chang Chia-Chi Wang Shiann Pan | 2005 | World Journal of Gastroenterology2005，11，24： | 6 |
| 3 | Management of hemangiomas of infancy:review of 245 patients显示文摘 | Achauer BM Chang CJ Vander Kam VM | 1997 | Plast Reconstr Surg1997，99，5： | 1 |
| 4 | Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation显示文摘 | Guo W Lasky JL Chang CJ | 2008 | Nature2008，453，7194： | 1 |
| 5 | Effects of tamsulosin on lower uri-nary tract symptoms due to double-J stent:a prospective study显示文摘 | Wang CJ Huang SW Chang CH | 2009 | U-rol Int2009，83，1： | 1 |
| 6 | Prevelence and risk factors of diabetic retinopathy among the noninsulin-dependent diabetics subjects显示文摘 | Chen MS Kao CS Chang CJ | 1992 | Am J Ophthalmol1992，114，： | 1 |
| 7 | Differentiation of benign and malignant cervical lymph nodes with color Doppler sonography显示文摘 | Chang DB Yuan A Tu CJ | 1994 | AJD1994，162，： | 1 |
| 8 | Influence of third-generation cephalosporin resistance on adult in-hospital mortal ity from post-neurosurgical bacterial meningitis显示文摘 | Chang CJ Ye J J Yang CC | 2010 | J Microbiol Immunol Infect2010，43，4： | 1 |
| 9 | The effectiveness of silver-releasing dressings in the management of non- healing chronic wounds : A meta analysis 显示文摘 | Lo SF Change CJ Hu WY | 2009 | Journal of Clinical Nursing2009，18，5： | 1 |
| 10 | Clinical implications of human papillomavirus genotype in cervical adeno -adenosquamous carcinoma显示文摘 | Lai CH Chou HH Chang CJ | 2013 | Eur J Cancer2013，49，3： | 1 |
| 11 | Three-Dimensional ultrasound in margin evaluation for breast tumor excision using mammotome显示文摘 | Chen DR Chang RF Chen CJ | 2004 | Ultrasound Med Biol2004，30，2： | 1 |
| 12 | Effect of calcium channel blockers on vertebral bone marrow perfusion of the lunbar spine显示文摘 | Shih TT Chang CJ Tseng WY | 2004 | Radiology2004，231，： | 1 |
| 13 | Management of heman- gioma of infancy : review of 245 patients 显示文摘 | Achauer BM Chang CJ Vander Kam VM | 1997 | Plast Reconstr Surg1997，99，5： | 1 |
| 14 | Significant difference in the trends of female breast cancer incidence between Taiwanese and Caucasian Americans: implications from age-period-cohort analysis显示文摘 | Shen YC Chang CJ Hsu C | 2005 | Cancer Epidemiol Biomarkers Prev2005，14，8： | 1 |
| 15 | p53 regulates epithelial- mesenchymal transition and stem cell properties through modulating miRNAs 显示文摘 | Chang CJ Chao CH Xia W | 2011 | Nat Cell Biol2011，13，3： | 1 |
| 16 | Suppressed transformation and induced differentiation of HER-2/neu-overexpressing breast cancer cells by emodin 显示文摘 | Zhang L Chang CJ Bacus SS | 1995 | Cancer Res1995，55，17： | 1 |
| 17 | Mechaniem of reducing platelet activity by percutaneous transluminal mitral valvuloplasty in patients with rheumatic mitral stenosis 显示文摘 | Chen MC Wu CJ Chang HW | 2004 | Chest2004，125，5： | 1 |
| 18 | Survival analysis in systemic lupus cry- thematosus patients on maintenance dialysis: a nationwide population- based study in Taiwan显示文摘 | Chang YS Liu CJ Wu TH | 2013 | Rheumatology (Oxford)2013，52，1： | 1 |
| 19 | Impact of mental health and car-egiver burden on family caregivers,physical health显示文摘 | Chang HY Chiou CJ Chen NS | 2010 | Archivesof Gerontology and Geriatrics2010，，26： | 1 |
| 20 | Replication and metaanalysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase(BLK)in disease susceptibility显示文摘 | Chang CJ Kuo HC Chang JS | 2013 | PLo S One2013，8，8： | 1 |
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