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7篇 您的检索式:作者名="Chander Kumar Singh"
    题名 作者 年代 出处 被引量
1Antibiotic Use in Agriculture and Its Impact on the Terrestrial Environment显示文摘Kuldip Kumar Satish C. Gupta Yogesh Chander Ashok K. Singh 2005Advances in Agronomy2005,,:1
2Design of Combretastatin A-4 Analogs as Tubulin Targeted Vascular Disrupting Agent with Special Emphasis on Their Cis-Restricted Isomers显示文摘Harish Rajak Pramod Kumar Dewangan Vijay Patel Deepak Kumar Jain Avineesh Singh Ravichandran Veerasamy Prabodh Chander Sharma Anshuman Dixit 2013Current Pharmaceutical Design2013,,10:1
3Neoadjuvant chemotherapy with weekly paclitaxel and carboplatin followed by chemoradiation in locally advanced cervical carcinoma: A pilot study显示文摘Rajkumar Bikramjit Singh Subhash Chander B.K. Mohanti Sushmita Pathy Sunesh Kumar Neerja Bhatla Sanjay Thulkar Sreenivas Vishnubhatla Lalit Kumar 2013Gynecologic Oncology2013,,:1
4Determining the genetic origin of nitrate contamination in aquifers of Northern Gujarat, India显示文摘Kumari Rina Datta P S Chander Kumar Singh 2014Environmental EarthSciences2014,71,4:1
5Enzyme-linked immunosorbent assay for ultratrace determination of antibiotics in aqueous samples显示文摘Kumar K Thompson A Singh A K Chander Y Gupta S C 0,,1:1
6Primary biliary cirrhosis in India显示文摘BACKGROUND: Primary biliary cirrhosis (PBC) is a rare cause of chronic liver disease in India. We analyzed the clinical, biochemical, serological and histological features of patients with PBC for over a 10-year period. METHODS: PBC was diagnosed by the presence of raised level of serum alkaline phosphatase (ALP), anti-mitochondrial antibody (AMA) positivity (1:40 dilution), and/or diagnostic liver histology. RESULTS:Fifteen female patients with mean age of 46.5±11 years were studied. Pruritis (80%) followed by jaundice (67%), skin changes (pigmentation, coarsening, xanthelesma and vitiligo) (67%) and fatigue (60%) were common symptoms. The mean duration of the symptoms was 3.5± 5.4 years (3 months to 20 years). Dryness of eyes was observed in only 2 patients. Hepatomegaly was noted in 87% of the patients and ascites at presentation in 40%. Mean levels of bilirubin and albumin at the time of diagnosis were 3.4±3.3 mg/dl and 3.5±0.8 g/dl, respectively. The level of serum ALP ranged from 54 to 2400 IU/L, with a median being 552 IU/L (2×ULN). In all the 15 patients with AMA positive, 8(53%) were also positive for either anti-nuclear or anti-smooth muscle antibodies. Two patients presented with persistently elevated SAP after an acute hepatitic illness. Liver biopsy was available in 13 patients, diagnostic of PBC Ⅱ & Ⅲ(8) and with evidence of cirrhosis (5). Associated autoimmune disorders were observed in 5 patients (33%). The mean time for follow-up was 26±21 months (1 to 87 months). In 4 deaths, 3 were due to liver related causes. CONCLUSION: PBC is a rare cause of chronic liver disease in India. PBC in India, unlike in the West, presents late, often with features of cirrhosis and decompensation.Shiv Kumar Sarin Rajnish Monga Bimaljeet Singh Sandhu Barjesh Chander Sharma Puja Sakhuja Veena Malhotra 2006Hepatobiliary & Pancreatic Diseases International2006,5,1:1
7Spectrum of fungal keratitis: clinicopathologic study of 44 cases显示文摘AIM: To determine the causative agents of fungal keratitis and study the predisposing factors over a period of ten years in a single tertiary care hospital. ·METHODS: A retrospective analysis of fungal corneal ulcers was done from 2003-2012. Patients' clinical data were noted from the file records. Correlation of histopathological diagnosis was done with the report on fungal culture. · RESULTS: Mycotic keratitis was established in 44 cases by a positive fungal culture. Direct microscopic examination of potassium hydroxide(KOH) mounts revealed fungal elements in 39 cases while 40 cases showed fungus on Gram stained smears. Males(54.55%) were more commonly affected than the females(45.45%). The age ranged from 18 to 82 years. Most common age group to be involved was 41-60 years. Predisposing risk factors were seen in 34(77.27%) cases. Most common findings on clinical examination were anterior chamber reaction and conjunctival injection seen in all the cases. Other common findings were stromal infiltration and hypopyon seen in 20(45.45%) and 18(40.91%) cases respectively. On histopathological examination the fungus was typed,as aspergillus in 34 cases while no definite typing was possible in 10 cases. The predominant isolate was aspergillus flavus(59.09%) followed by fusarium(15.91%). Mixed fungal and bacterial infection was seen in 3(6.82%) cases. ·CONCLUSION: Although culture is the gold standard for definitive diagnosis of fungal keratitis,direct microscopic examination of corneal scrapings or histomorphological evaluation of biopsies allow a rapidpreliminary diagnosis. Early administration of antifungal treatment helps in preventing dreadful complications.Rajpal Singh Punia Reetu Kundu Jagdish Chander Sudesh Kumar Arya Uma Handa Harsh Mohan 2014International Journal of Ophthalmology(English edition)2014,7,1:0
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