|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Antidiabetic therapy and increased risk of hepatocellular carcinoma in chronic liver disease显示文摘AIM:To explore the association between hepatocellular carcinoma(HCC) and type 2 diabetes mellitus, describe the temporal relations between the onset of diabetes and the development of HCC and evaluate the possible effects of antidiabetic therapy on HCC risk.METHODS:We recruited 465 HCC patients, 618 with cirrhosis and 490 control subjects.We evaluated the odds ratio(OR) for HCC by univariate and multivariate analysis.Moreover, OR for HCC in diabetic subjects treated with insulin or sulphanylureas and with metformin were calculated.RESULTS:The prevalence of diabetes mellitus was 31.2% in HCC, 23.3% in cirrhotic patients and 12.7% in the Control group.By univariate and multivariate analysis, the OR for HCC in diabetic patients were respectively 3.12(CI 2.2-4.4, P < 0.001) and 2.2(CI 1.2-4.4, P = 0.01).In 84.9% of cases, type 2 diabetes mellitus was present before the diagnosis of HCC.Moreover, we report an OR for HCC of 2.99(CI 1.34-6.65, P = 0.007) in diabetic patients treated with insulin or sulphanylureas, and an OR of 0.33(CI 0.1-0.7, P = 0.006) in diabetic patients treated with metformin.CONCLUSION:Our study confi rms that type 2 diabetes mellitus is an independent risk factor for HCC and pre-exists in the majority of HCC patients.Moreover, in male patients with type 2 diabetes mellitus, our data shows a direct association of HCC with insulin and sulphanylureas treatment and an inverse relationship with metformin therapy. | Valter Donadon Massimiliano Balbi Michela Ghersetti Silvia Grazioli Antonio Perciaccante Giovanni Della Valentina Rita Gardenal Maria Dal Mas Pietro Casarin Giorgio Zanette Cesare Miranda | 2009 | World Journal of Gastroenterology2009，15，20： | 23 |
| 2 | Current status and future perspectives of radiomics in hepatocellular carcinoma显示文摘Given the frequent co-existence of an aggressive tumor and underlying chronic liver disease,the management of hepatocellular carcinoma(HCC)patients requires experienced multidisciplinary team discussion.Moreover,imaging plays a key role in the diagnosis,staging,restaging,and surveillance of HCC.Currently,imaging assessment of HCC entails the assessment of qualitative characteristics which are prone to inter-reader variability.Radiomics is an emerging field that extracts high-dimensional mineable quantitative features that cannot be assessed visually with the naked eye from medical imaging.The main potential applications of radiomic models in HCC are to predict histology,response to treatment,genetic signature,recurrence,and survival.Despite the encouraging results to date,there are challenges and limitations that need to be overcome before radiomics implementation in clinical practice.The purpose of this article is to review the main concepts and challenges pertaining to radiomics,and to review recent studies and potential applications of radiomics in HCC. | Joao Miranda Natally Horvat Gilton Marques Fonseca Jose de Arimateia Batista Araujo-Filho Maria ClaraFernandes Charlotte Charbel Jayasree Chakraborty Fabricio Ferreira Coelho Cesar Higa Nomura Paulo Herman | 2023 | World Journal of Gastroenterology2023，29，1： | 3 |
| 3 | Flexible Ureteroscopy With a Ureteral Access Sheath: When to Stent?显示文摘 | Fabio Cesar Miranda Torricelli Shubha De Bryan Hinck Mark Noble Manoj Monga | 2013 | Urology2013，，： | 2 |
| 4 | Relationship be- tween fi'aeture Ioughness and flexural strength in dental porcelains 显示文摘 | Cesar PF Yoshimura HN Miranda WG Jr | 2006 | J Biomed Mater Res B Appl Biomater2006，78，2： | 1 |
| 5 | Evaluation of the adaptation of zirconia-based fixed partial dentures using micro- CT technology显示文摘 | Borba M Miranda WG Jr Cesar PF | 2013 | Braz Oral Res2013，27，5： | 1 |
| 6 | Effect of ion exchange on hardness and fracture toughness of dental porcelains 显示文摘 | Cesar PF Gonzaga CC Miranda WG Jr | 2007 | J Biomed Mater Res B Appl Biomater2007，83，2： | 1 |
| 7 | Different patterns between mechanical and electrical activities: an approach to investigate gastric motility in a model of long-term diabetic rats显示文摘 | Rozemeire G Marques Madileine F Americo Cesar T Spadella Luciana A Corá Ricardo B Oliveira Jose Ricardo A Miranda | 2014 | Physiological Measurement2014，，1： | 1 |
| 8 | Correlation between fracture toughness and leucite content in dental porcelains 显示文摘 | Cesar PF Yoshimura HN Miranda Junior WG | 2005 | J Dent2005，33，9： | 1 |
| 9 | Truffle thio-flavours reversibly inhibit truffle tyrosinase显示文摘 | Osvaldo Zarivi Antonella Bonfigli Patrizia Cesare Fernanda Amicarelli Giovanni Pacioni Michele Miranda | 2003 | FEMS Microbiology Letters2003，，1： | 1 |
| 10 | Relationship between fracture toughness and flexural strength in dental porcelains显示文摘 | Cesar PF Yoshimura HN Miranda WG | 2006 | J Biomed Mater Res B Apple Biomater2006，78，2： | 1 |
| 11 | Urolithiasis in Horseshoe Kidney With Duplex Collecting System显示文摘 | Fabio Cesar Miranda Torricelli Manoj Monga | 2013 | Urology2013，，： | 1 |
| 12 | Correlation be- tween fracture toughness and ]eucite content in dental pnrcelaions 显示文摘 | Cesar PF Yoshimura HN Miranda WG Jr | 2005 | J Dent2005，33，9： | 1 |
| 13 | Potential strategies offered by animals to implement in buildings' energy performance: Theory and practice显示文摘The strategies for thermal regulation and envir on mental control found in nature are countless. In this article, a parallelism between animals and building energy systems is defined in order to identJfy and emphasize the immediate opportunities that biomimicry offers for future research. The motivation was the need to find alternative solutions to tackle problems mainly in the efficiency of heating, ventilation and cooling systems. Due to the wide range of possibilities offered by animals, this study is largely limited to the strategies that cold-blooded animals have developed through evolutionary adaptation to the environment. The method used for the an a lysis is based on a soluti on-based approach. Firstly, differe nt animal thermoregulation strategies are defined (biological domain). Then the strategy is an a lyzed and classified into three categories. This classification is esse ntial in order to formulate the parallelism with building systems (transfer phase). The final step is to identify the potential implementation (technological domain).This approach has been seen to be useful in creating new research opportunities based on biomimicry. In addition, suitable solutions arising from multidisciplinary team research are presented as promising answers to the challenges that building energy systems face no wadays. | Cesar Martin-Gomez Amaia Zuazua-Ros Javier Bermejo-Busto Enrique Baquero Rafael Miranda Cristina Sanz | 2019 | Frontiers of Architectural Research2019，8，1： | 0 |
| 14 | Nutritional supplementation on wound healing in diabetic foot:What is known and what is new?显示文摘Non-healing diabetic foot ulcers(DFU)are the most notable and striking complications of diabetes mellitus.More than 25% of nonhealing DFU can ultimately lead to amputation of the lower extremity within 6-18 mo after the first manifestation of the wound.Although wound healing is complex,nutritional status is crucial in soft tissue repair.Malnutrition is highly prevalent and overlooked in patients with diabetes and chronic wounds.Moreover,to date,we do not have clear recommendations or evidence about the use of nutritional supplements for improving wound healing in patients with DFU.In this article the authors briefly analyzed the current evidence on the use of nutritional supplements of proteins or amino acids,fatty acids,probiotics,vitamins,and trace elements in the wound healing process in patients with DFU. | Andrea Da Porto Cesare Miranda Gabriele Brosolo Giorgio Zanette Andrea Michelli Roberto Da Ros | 2022 | World Journal of Diabetes2022，13，11： | 0 |
| 15 | Minimally invasive tenodesis for peroneus longus tendon rupture: A case report and review of literature显示文摘BACKGROUND Peroneal tendon disorders are common causes of lateral hindfoot pain.However,total rupture of the peroneal longus tendon is rare.Surgical treatment for this condition is usually a side-to-side tenodesis of the peroneal longus tendon to the peroneal brevis tendon.While the traditional procedure involves a long lateral curved incision,this approach is associated with damage to the lateral soft tissues(up to 24%incidence).CASE SUMMARY A 50-year-old female had developed pain at the lateral aspect of the hindfoot 1 mo after an ankle sprain while walking in the street.Previous treatments were anti-inflammatory drugs,ice,rest and Cam-walker boot.At physical exam,there was pain and swelling over the course of the peroneal tendons.Ankle instability and cavovarus foot deformity were ruled out.Eversion strength was weak(4/5).Imaging showed complete rupture of the peroneal longus tendon associated with a sharp hypertrophic peroneal tubercle.Surgical repair was indicated after failure of conservative treatment(physiotherapy,rest,analgesics,and ankle stabilizer).A less invasive approach was performed for peroneal longus tendon debridement and side-to-side tenodesis to the adjacent peroneal brevis tendon,with successful clinical and functional outcomes.CONCLUSION Peroneus longus tendon tenodesis can be performed through a less invasive approach with preservation of the lateral soft tissue integrity. | Danilo Ryuko Cândido Nishikawa Fernando Aires Duarte Guilherme Honda Saito Cesar de Cesar Netto Fábio Correia Paiva Fonseca Bruno Rodrigues de Miranda Augusto César Monteiro Marcelo Pires Prado | 2020 | World Journal of Orthopedics2020，11，2： | 0 |
| 16 | Application of Automatic Mass Balance in Metal Accounting of Iron Ore Plant显示文摘 | Rodrigo Cesar de Miranda Marco Aurelio Soares Martins Hugo Montalvao Gontijo Plinio Cruz Gianeli Bruna Torres Negreiros Cordeiro Andrade | 2013 | Journal of Environmental Science and Engineering(A)2013，2，2： | 0 |
| 17 | Surgical treatment of cementoblastoma associated with apicoectomy and endodontic therapy:Case report显示文摘This case report describes the surgical removal of cementoblastoma associated with apicoectomy and endodontic therapy. The patient, an 18-year-old man, presented pain in the region of the mandibular body on the right side. On clinical exam, bone expansion was observed in the region at the bottom of the vestibular sulcus, pain on palpation, slight extrusion of tooth 46 with presence of pulp vitality. Radiographic exams demonstrated the presence of a radiopaque area and discrete radiolucent halo associated with the root of tooth 46, suggesting the diagnosis of cementoblastoma. Endodontic treatment of tooth 46 was performed and exeresis of the lesion by apicoectomy. Twelve months after the first surgery, recurrence of the lesion was observed, and a new apicoectomy was necessary, this time up to the middle third of the root. Clinical radiographic control 12 mo after the second surgical intervention demonstrated absence of signs and symptoms, radiographic repair, with tooth 46 shown to be fully functional. | Bernardo Cesar Costa Guilherme José Pimentel Lopes de Oliveira Maria das Gra?as Afonso Miranda Chaves Renan Roberto da Costa Mário Francisco Real Gabrielli Juliane Maria Guerreiro-Tanomaru Mário Tanomaru-Filho | 2016 | World Journal of Clinical Cases2016，4，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员