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| 1 | CanTree:a canonical-order tree for incremental pattern mining显示文摘 | Leung Carson Kai-Sang Khan Quamrul I Li Zhan | | 0,,03: | 1 |
| 2 | CanTree: A canonical-order tree for incremental frequent pattern mining 显示文摘 | Leung Carson Kai-Sang Khan Quamrul I Li Zhan | 2007 | Knowledge Information System2007,11,3: | 1 |
| 3 | Multiparametric MRI reporting using Prostate Imaging Reporting and Data System version 2.0 (PI-RADSv2) retains clinical efficacy in a predominantly post-biopsy patient population显示文摘Objective:To evaluate the efficacy of multiparametric magnetic resonance imaging(mp-MRI)using Prostate Imaging Reporting and Data System version 2.0(PI-RADSv2)definitions in detecting organ-confined prostate cancer.Methods:All patients who underwent radical prostatectomy between January 1,2014 and December 30,2014 were identified.All underwent mp-MRI within 180 days before surgery.Those with prior pelvic irradiation or androgen deprivation therapy were excluded.Fully embedded,whole-mount histopathology was centrally reviewed and correlated with imaging for tumour location,Gleason score(GS)and stage.Results:There were 39 patients included,of which 35(90%)had mp-MRI done post-biopsy.A total of 93 cancer foci were identified on whole-mount pathology,of which mp-MRI detected 63(68%).Of those detected by mp-MRI,14 were PI-RADS 3(n=6 for GS 6,n=8 for GS 7,no GS≥8)and 49 were PI-RADS 4e5(nZ7 for GS 6,nZ33 for GS 7,and nZ9 for GS≥8).There were 30(32%)cancer foci missed by mp-MRI(n=15 for GS 6,n=13 for GS 7 and n=2 for GS≥8).A lesion classified as PI-RADS 4e5 predicted a higher grade cancer on pathology as compared to PI-RADS 3(for GS 7 lesions,odds ratio[OR]=3.53,95%CI:0.93e13.45,p=0.064).The mp-MRI size detection limit was 20 mm2 and 100 mm2 for 50%and 75%probability of cancer,respectively.In associating with radiological and pathologic stage,the weighted Kappa value was 0.69(p<0.0001).The sensitivity and positive predictive values for this study were 68%(95%CI:57%e77%)and 78%(95%CI:67%e86%),respectively.Conclusion:In this predominantly post-biopsy cohort,mp-MRI using PI-RADSv2 reporting has a reasonably high diagnostic accuracy in detecting clinically significant prostate cancer. | Edwin Jonathan Aslim Yan Mee Law Puay Hoon Tan John Carson Allen Jr Lionel Tim-Ee Cheng Viswanath Anand Chidambaram Li Yan Khor Benjamin Yongcheng Tan Ernest Wencong Eu Christopher Wai Sam Cheng John Shyi Peng Yuen Henry Sun Sien Ho Lui Shiong Lee | 2019 | Asian Journal of Urology2019,6,3: | 1 |
| 4 | Assessing environmental support for better health: Active living opportunity audits in rural communities in the southern United States显示文摘 | Jennifer C. Robinson Tiffany L. Carson Erica R. Johnson Claudia M. Hardy James M. Shikany Eva Green Lillie M. Willis John V. Marron Yufeng Li Choo Hyung Lee Monica L. Baskin | 2014 | Preventive Medicine2014,,: | 1 |
| 5 | Parathyroid hormone-stimulated resorption in calvaria cultured in serum-free medium is enhanced by the calcium-mobilizing activity of 1,25-dihydroxyvitamin D(3)显示文摘 | Li W Farach Carson M C | 2001 | Bone2001,29,3: | 1 |
| 6 | Histopathological analysis of infiltrating T cell subsets in acute T cell-mediated rejection in the kidney transplant显示文摘AIM To compare the differential immune T cell subset com-position in patients with acute T cell-mediated rejection in the kidney transplant with subset composition in the absence of rejection, and to explore the association of their respective immune profiles with kidney transplant outcomes.METHODS A pilot cross-sectional histopathological analysis of the immune infiltrate was performed using immunohistochemistry in a cohort of 14 patients with acute T cellmediated rejection in the kidney transplant and 7 kidney transplant patients with no rejection subjected to biopsy to investigate acute kidney transplant dysfunction. All patients were recruited consecutively from 2012 to 2014 at the Singapore General Hospital. Association of the immune infiltrates with kidney transplant outcomes at up to 54 mo of follow up was also explored prospectively.RESULTS In a comparison to the absence of rejection, acute T cell-mediated rejection in the kidney transplant was characterised by numerical dominance of cytotoxic T lymphocytes over Foxp3^+ regulatory T cells, but did not reach statistical significance owing to the small sample size in our pilot study. There was no obvious difference in absolute numbers of infiltrating cytotoxic T lymphocytes, Foxp3^+ regulatory T cells and Th17 cells between the two patient groups when quantified separately. Our exploratory analysis on associations of T cell subset quantifications with kidney transplant outcomes revealed that the degree of Th17 cell infiltration was significantly associated with shorter time to doubling of creatinine and shorter time to transplant loss.CONCLUSION Although this was a small pilot study, results support our suspicion that in kidney transplant patients the immune balance in acute T cell-mediated rejection is tilted towards the pro-rejection forces and prompt larger and more sophisticated studies. | Francisco Salcido-Ochoa Susan Swee-Shan Hue Siyu Peng Zhaoxiang Fan Reiko Lixiang Li Jabed Iqbal John Carson Allen Jr Alwin Hwai Liang Loh | 2017 | World Journal of Transplantation2017,7,4: | 1 |
| 7 | Quantum state and process tomography via adaptive measurements显示文摘We investigate quantum state tomography(QST) for pure states and quantum process tomography(QPT) for unitary channels via adaptive measurements. For a quantum system with a d-dimensional Hilbert space, we first propose an adaptive protocol where only 2d. 1 measurement outcomes are used to accomplish the QST for all pure states. This idea is then extended to study QPT for unitary channels, where an adaptive unitary process tomography(AUPT) protocol of d2+d.1measurement outcomes is constructed for any unitary channel. We experimentally implement the AUPT protocol in a 2-qubit nuclear magnetic resonance system. We examine the performance of the AUPT protocol when applied to Hadamard gate, T gate(/8 phase gate), and controlled-NOT gate,respectively, as these gates form the universal gate set for quantum information processing purpose. As a comparison, standard QPT is also implemented for each gate. Our experimental results show that the AUPT protocol that reconstructing unitary channels via adaptive measurements significantly reduce the number of experiments required by standard QPT without considerable loss of fidelity. | HengYan Wang WenQiang Zheng NengKun Yu KeRen Li DaWei Lu Tao Xin Carson Li ZhengFeng Ji David Kribs Bei Zeng XinHua Peng JiangFeng Du | 2016 | Science China(Physics,Mechanics & Astronomy)2016,59,10: | 0 |