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| 1 | 汉语普通话中双焦点的产出及其感知显示文摘以往的研究发现双焦点句中第一个焦点后往往缺少音高压缩。这一现象是否与两个焦点间的音节数有关?实验控制了焦点词的位置和句子长度两个因素,发现双焦点句中两个焦点既相互独立又相互依存.独立性表现为每个焦点有各自的实现范围,其音高升高和时长延长都和所对应的单焦点的条件接近;依存性表现为两个焦点可以在同一个语调短语内共存。第一个焦点后因为有了韵律短语边界而缺少音高压缩,而与两个焦点间的音节数没有直接关系。感知实验的结果显示:双焦点的辨认正确率显著低于句首单焦点。这主要因为同时判别两个焦点的难度比较高。如果只要求听音人关注第一个焦点,其辨认率明显提高,且与句首单焦点的判断正确率无显著差异。可见,在双焦点句中,句首和句末焦点的判断有不对称性。音高和时长的增加可以保证句首焦点的正确感知,但不能保证句末焦点的正确感知。总体来说,两个焦点中句首焦点在感知上有更高的突显度。 | 王蓓 刘璐 张夏夏 Caroline Féry | 2019 | 声学学报2019，44，1： | 3 |
| 2 | Infectious, atopic and inflammatory diseases, childhood adversities and familial aggregation are independently associated with the risk for mental disorders: Results from a large Swiss epidemiological study显示文摘AIM To examine the associations between mental disorders and infectious, atopic, inflammatory diseases while adjusting for other risk factors.METHODS We used data from PsyC oL aus, a large Swiss Population Cohort Study(n = 3720; age range 35-66). Lifetime diagnoses of mental disorders were grouped into the following categories: Neurodevelopmental, anxiety(early and late onset), mood and substance disorders. They were regressed on infectious, atopic and other inflammatory diseases adjusting for sex, educational level, familial aggregation, childhood adversities and traumatic experiences in childhood. A multivariate logistic regression was applied to each group of disorders. In a complementary analysis interactions with sex were introduced via nested effects. RESULTS Associations with infectious, atopic and other chronic inflammatory diseases were observable together with consistent effects of childhood adversities and familial aggregation, and less consistent effects of trauma in each group of mental disorders. Streptococcal infections were associated with neurodevelopmental disorders(men), and measles/mumps/rubella-infections with early and late anxiety disorders(women). Gastric inflammatory diseases took effect in mood disorders(both sexes) and in early disorders(men). Similarly, irritable bowel syndrome was prominent in a sex-specific way in mood disorders in women, and, moreover, was associated with early and late anxiety disorders. Atopic diseases were associated with late anxiety disorders. Acne(associations with mood disorders in men) and psoriasis(associations with early anxiety disorders in men and mood disorders in women) contributed sex-specific results. Urinary tract infections were associated with mood disorders and, in addition, in a sex-specific way with late anxiety disorders(men), and neurodevelopmental and early anxiety disorders(women).CONCLUSION Infectious, atopic and inflammatory diseases areimportant risk factors for all groups of mental disorders. The sexual dimorphism of the associations is pronounced. | Vladeta Ajdacic-Gross Aleksandra Aleksandrowicz Stephanie Rodgers Margot Mutsch Anja Tesic Mario Müller Wolfram Kawohl Wulf R?ssler Erich Seifritz Enrique Castelao Marie-Pierre F Strippoli Caroline Vandeleur Roland von K?nel Rosa Paolicelli Markus A Landolt Cornelia Witthauer Roselind Lieb Martin Preisig | 2016 | World Journal of Psychiatry2016，6，4： | 2 |
| 3 | From azoospermia to macrozoospermia,a phenotypic continuum due to mutations in the ZMYND15 gene显示文摘Thanks to tremendous advances in sequencing technologies and in particular to whole exome sequencing(WES),many genes have now been linked to severe sperm defects.A precise genetic diagnosis is obtained for a minority of patients and only for the most severe defects like azoospermia or macrozoospermia which is very often due to defects in the aurora kinase C(AURKC)gene.Here,we studied a subject with a severe oligozoospermia and a phenotypic diagnosis of macrozoospermia.AURKC analysis did not reveal any deleterious variant.WES was then initiated which permitted to identify a homozygous loss of function variant in the zinc finger MYND-type containing 15(ZMYND15)gene.ZMYND15 has been described to serve as a switch for haploid gene expression,and mice devoid of ZMYND15 were shown to be sterile due to nonobstructive azoospermia(NOA).In man,ZMYND15 has been associated with NOA and severe oligozoospermia.We confirm here that the presence of a bi-allelic ZMYND15 variant induces a severe oligozoospermia.In addition,we show that severe oligozoospermia can be associated macrozoospermia,and that a phenotypic misdiagnosis is possible,potentially delaying the genetic diagnosis.In conclusion,genetic defects in ZMYND15 can induce complete NOA or severe oligozoospermia associated with a very severe teratozoospermia.In our experience,severe oligozoospermia is often associated with severe teratozoospermia and can sometimes be misinterpreted as macrozoospermia or globozoospermia.In these instances,specific AURKC or dpy-19 like 2(DPY19L2)diagnosis is usually negative and we recommend the direct use of a pan-genomic techniques such as WES. | Zine-Eddine Kherraf Caroline Cazin Florence Lestrade Jana Muronova Charles Coutton Christophe Arnoult Nicolas Thierry-Mieg Pierre F Ray | 2022 | Asian Journal of Andrology2022，24，3： | 2 |
| 4 | Hypoxia-inducible factor-1 and activator protein-1 modulate the upregulation of CYP3A6 induced by hypoxia显示文摘 | Caroline F Patrick DS | 2003 | British Journal of Pharmacology2003，140，6： | 1 |
| 5 | maternal and child undemutrition: Consequcnces for adult health and human capital 显示文摘 | CESAR G V LINDA A CAROLINE F | 2008 | The lancet2008，371，9607： | 1 |
| 6 | Recombinant tissue-type plasminogen activator therapy of thrombosis in 16 neonates显示文摘 | Caroline F Odile C Didier P | 1998 | Pediatrics1998，133，1： | 1 |
| 7 | Lipoxin A(4) regulates bronchial epithelial cell responses to acid injury显示文摘 | Caroline B Koiehi F | 2006 | Am J Pathol2006，168，4： | 1 |
| 8 | Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization显示文摘 | Ahaun S Amy F Caroline RB | 2012 | Immunity2012，38，1： | 1 |
| 9 | Reduced Number of Circulating Endothelial Progenitor Cells Predicts Future Cardiovascular Events: Proof of Concept for the Clinical Importance of Endogenous Vascular Repair显示文摘 | Caroline SL Lothar R Stephan F | 2005 | Circulation2005，111，22： | 1 |
| 10 | The intra-and inter-la- boratory reproducibility and predictivity of the KeratinoSens assay to predict skin sensitizers in vitro : results of a ring- study in five laboratories显示文摘 | Andreas N Caroline B Leslie F | 2011 | Toxicol In Vitro2011，25，3： | 1 |
| 11 | Solid phase microextraction (SPME) combined with gas-chromatography and olfactometry-mass spectrometry for characterization of cheese aroma compounds显示文摘 | DAMIAN C F CAROLINE M O JOHN P | 2004 | LWT2004，37，2： | 1 |
| 12 | Differential effects of short-term treatment with two AT1 receptor blockers on diameter of pial arterioles in SHR显示文摘 | Sébastien F Franeois Du Caroline PS | | 0，，09： | 1 |
| 13 | Long distance running increases plantar pressures beneath the metatarsal heads: A barefoot walking investigation of 200 marathon runners显示文摘 | Arne N Frauke F Carolin K | 2008 | Gait Posture2008，27，1： | 1 |
| 14 | Role of the Raf signal transduetion cascade in the in vitro resistance to the anticancer drug doxorubicin显示文摘 | Caroline R Carlos F Patrick M | 2001 | Clin Caner Res2001，46，7： | 1 |
| 15 | Three-dimensionalspeckle - tracking echocardiography for automatic assessment ofglobal and regional left ventricular function based on area strain显示文摘 | Sebastiaan A Mohamed F Caroline B | 2011 | J Am Soc Echocardiogr2011，24，3： | 1 |
| 16 | Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi显示文摘 | Ana Carolina Alves de Paula e Silva Caroline Barcelos Costa-Orlandi Fernanda Patrícia Gullo Fernanda Sangalli-Leite Haroldo Cesar de Oliveira Julhiany de Fátima da Silva Liliana Scorzoni Nayla de Souza Pitangui Suélen Andrea Rossi Tatiane Benaducci Vaness | 2014 | Evidence-Based Complementary and Alternative Medicine2014，，： | 1 |
| 17 | Viral etiologies of lower respiratory tract infections a- mong Egyptian children under five years of age显示文摘 | Shafik Caroline F Mohareb Emad W Yassin Aymen S | 2013 | BMC Infectious Diseases2013，12，1： | 1 |
| 18 | Highhydrostatic pressure activates gene expression through Msn2/4 stress transcription factors which are involved in the acquired tolerance by mild pressure precondition in Saccharomyces cerevisiae显示文摘 | Tatiana D Caroline M F Emmanuelle B M | | 0，，： | 1 |
| 19 | Twenty Years of Pediatric Tuberculous Meningitis:Aretrospective Cohort Study in the Western Cape of South Africa显示文摘 | Gijs TJ van Well Berbe F Paes Caroline B Terwee | | 0，，01： | 1 |
| 20 | Filter backwash and start-up strategies for enhanced particulate removal显示文摘 | JASON F C PETER H CAROLINE S B | 1996 | Water Research1996，30，10： | 1 |
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