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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | 百乐锌与氧化锌的比较试验:减少猪饲粮中的锌添加量同时维持猪的生长性能显示文摘猪的饲料原料通常含有适量浓度的锌(Zn)似乎可以满足猪对Zn的需要。研究证实,高浓度饲粮锌能刺激保育猪的生长和改善饲料利用率。但是,近年来养殖业日渐意识到饲粮中高浓度的矿物质会引起环境问题。人们也日益关注使用有机微量元素作为一种减少矿物质添加量和排泄量的方法。Wedekind(1990,1992)的试验表明,与硫酸锌(100%)相比,蛋氨酸锌(Zn—Met)的生物学效价在117%~206%。 | Carlson M S Veum T L 汪静霞 | 2007 | 养猪2007，，3： | 2 |
| 3 | Modeling and control of magnetorheological dampers forseismic response reduction 显示文摘 | DYKE S J SPENCER B F SAIN M K CARLSON J D | 1996 | Smart Materials and Structures1996，5，5： | 2 |
| 4 | Inhibitionof a signaling pathway in cardiac muscle cells by active mitogen-activated protein kinase kinase显示文摘 | Thorburn J Carlson M Mansour SJ | 1995 | Mol Biol Cell1995，6，： | 1 |
| 5 | ECP:molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease显示文摘 | Bystrom J Carlson M | 1999 | 29(9):1172-11861999，29，9： | 1 |
| 6 | Effects of bolus injection of esmolol in healthy,exercising subjects显示文摘 | Carlson L Gold MD | 1991 | Anesth Analg1991，72，： | 1 |
| 7 | Remote Estimation of Sell Moisture Availability and Fractional Vegetation Cover for Agricultural Fields显示文摘 | Perry E M Schmugge T J | 1990 | Agriculture and Forest Meteorology1990，52，12： | 1 |
| 8 | A randomized,wait-list controlled clinical trial:The effect of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients显示文摘 | Speca M Carlson LE Goodey E | 2000 | Psychosomat Med2000，62，5： | 1 |
| 9 | Sentinel lymph node biopsy for breast cancer: a suitable alternative to routine axillary dissection in multi-inatitutional practice when optimal technique is used显示文摘 | MCMASTERS K M TUTTLE T M CARLSON D J | 2000 | J Clin Oncel2000，18，13： | 1 |
| 10 | Chromosomal distribution of en- dogenous Jaagsiekte sheep retrovirus proviral sequences in the sheep genome 显示文摘 | Carlson J Lyon M Bishop J | 2003 | J Virol2003，77，17： | 1 |
| 11 | Evidence that physiLologic levels of circulating estrogens and neonatal sex-imprinting modify postpubertal hepatic microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase acivity显示文摘 | Carlson S E Mitchell A D Carter M L | 1980 | Biochem Biophys Acta1980，633，： | 1 |
| 12 | Discrete Equilibrium Price Dispersion显示文摘 | CARLSON J PRESTON M | 1983 | Journal of Political Economy1983，，： | 1 |
| 13 | Rigid fluid:animation the interplay between rigid bodies and fluid显示文摘 | Carlson M Mucha P J Turk G | 2004 | ACM Transactions on Graphics2004，23，3： | 1 |
| 14 | Federated Kalman Filter Sim- ulation Results显示文摘 | Carlson N A Berarduccl M P | 1994 | Navigation1994，28，3： | 1 |
| 15 | Stem cell therapy restores transparency to defective murine corneas显示文摘 | Du Y Carlson E C Funderburgh M L | | 0，，07： | 1 |
| 16 | Determining data informa- tion literacy needs: A study of students and research faculty 显示文摘 | Carlson J Fosmire M Miller C C | 2011 | por- tal: Libraries and the Academy2011，11，2： | 1 |
| 17 | Complexity and robustness 显示文摘 | Carlson J M Doyle J | 2002 | Proc National of Academac SCI2002，99，1： | 1 |
| 18 | Construction and initial validation of a multidimensional measure of work - family conflict 显示文摘 | Carlson D S Kacmar K M Williams L J | 2000 | Journal of Vocational Behavior2000，56，2： | 1 |
| 19 | Characterization of vitellogenin from white sturgeon Acipenser transmontanus 显示文摘 | BidweU C A Carlson D M | 1995 | Mol Evol1995，41，1： | 1 |
| 20 | Properties and applications of commercial magnetorheological fluids 显示文摘 | JOLLY M R BENDER J W CARLSON D J | 2000 | Journal of Intelligent Material Systems and Struc- tures2000，10，11： | 1 |
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