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| 1 | Exploring alternative treatments for Helicobacter pylori infection显示文摘Helicobacter pylori(H. pylori) is a successful pathogen that can persist in the stomach of an infected person for their entire life. It provokes chronic gastric inflammation that leads to the development of serious gastric diseases such as peptic ulcers, gastric cancer and Mucosa associated lymphoid tissue lymphoma. It is known that these ailments can be avoided if the infection by the bacteria can be prevented or eradicated. Currently, numerous antibiotic-based therapies are available. However, these therapies have several inherent problems, including the appearance of resistance to the antibiotics used and associated adverse effects, the risk of re-infection and the high cost of antibiotic therapy. The delay in developing a vaccine to prevent or eradicate the infection has furthered research into new therapeutic approaches. This review summarises the most relevant recent studies on vaccine development and new treatments using natural resources such as plants, probiotics and nutraceuticals. In addition, novel alternatives based on microorganisms, peptides, polysaccharides, and intragastric violet light irradiation are presented. Alternative therapies have not been effective in eradicating the bacteria but have been shown to maintain low bacterial levels. Nevertheless, some of them are useful in preventing the adverse effects of antibiotics, modulating the immune response, gastroprotection, and the general promotion of health. Therefore, those agents can be used as adjuvants of allopathic anti-H. pylori eradication therapy. | Guadalupe Ayala Wendy Itzel Escobedo-Hinojosa Carlos Felipe de la Cruz-Herrera Irma Romero | 2014 | World Journal of Gastroenterology2014，20，6： | 16 |
| 2 | 形成性评价(Formative Assessment)的本质及其对教与学的影响显示文摘长期以来,很多学者一直倡导指导教学的评价,即通过评估学生需求和监测其学习进展,适当地设计学习顺序,调整教学策略,改良学习计划,以便有效地促进学习目标的完成。本研究调查了形成性评价在美国中学科学课中的实施情况,并分析其对学生学习进步的影响。研究表明,教师都在努力使用形成性评价来指导教学,而学生取得的成绩各不相同。 | Joan L.Herman Ellen Osmundson Carlos Ayala Stephen Schneider Mike Timms 杜承达 | 2010 | 考试研究2010，6，1： | 12 |
| 3 | Chronotherapy of hypertension: Administration-time-dependent effects of treatment on the circadian pattern of blood pressure显示文摘 | Ramón C. Hermida Diana E. Ayala Carlos Calvo Francesco Portaluppi Michael H. Smolensky | 2007 | Advanced Drug Delivery Reviews2007，，9： | 1 |
| 4 | Seasonal Variation of Fibrinogen in Dipper and Nondipper Hypertensive Patients显示文摘 | Ramón C. Hermida Carlos Calvo Diana E. Ayala José E. López José R. Fernández Artemio Mojón María J. Domínguez Manuel Covelo | 2003 | Circulation: Journal of the American Heart Association2003，，9： | 1 |
| 5 | Decrease in Urinary Albumin Excretion Associated With the Normalization of Nocturnal Blood Pressure in Hypertensive Subjects显示文摘 | Ramón C. Hermida Carlos Calvo Diana E. Ayala José E. López | 2005 | Hypertension ( Part Suppl)2005，，4： | 1 |
| 6 | Reagent-free determination of amikacin content in amikacin sulfate injections by FTIR derivative spectroscopy in a continuous flow system显示文摘The quantitative estimation of amikacin(AMK) in AMK sulfate injection samples is reported using FTIR-derivative spectrometric method in a continuous flow system. Fourier transform of mid-IR spectra were recorded without any sample pretreatment. A good linear calibration(r>0.999, %RSD<2.0) in the range of 7.7–77.0 mg/mL was found. The results showed a good correlation with the manufacturer's and overall they all fell within acceptable limits of most pharmacopoeial monographs on AMK sulfate. | José F.Ovalles Máximo Gallignani María R.Brunetto Rebeca A.Rondón Carlos Ayala | 2014 | Journal of Pharmaceutical Analysis2014，4，2： | 1 |
| 7 | Administration time-dependent effects of amlodipine on ambulatory blood pressure in patients with essential hypertension 显示文摘 | Ramon Hermida C Carlos C Diana Ayala E | 2005 | Am J Hypertens2005，18，5： | 1 |
| 8 | Chronotherapy Improves Blood Pressure Control and Reverts the Nondipper Pattern in Patients With Resistant Hypertension显示文摘 | Ramón C. Hermida Diana E. Ayala José R. Fernández Carlos Calvo | 2008 | Hypertension2008，，1： | 1 |
| 9 | Effects of Time of Day of Treatment on Ambulatory Blood Pressure Pattern of Patients With Resistant Hypertension显示文摘 | Ramón C. Hermida Diana E. Ayala Carlos Calvo José E. López Artemio Mojón María J. Fontao Rita Soler José R. Fernández | 2005 | Hypertension ( Part Suppl)2005，，4： | 1 |
| 10 | Analysis and Prediction of Risks From Rockfall in the Huancavelica City显示文摘This research refers to the analysis and prediction of rockfall risk,whose objective is to determine the results of the validation of the model and application of modeling in the Rocfall Software,in this way to prepare the map of risk areas.Likewise,the general problem was identified:What are the results of the analysis and prediction of risks from rockfall in the city of Huancavelica?To respond to the problem posed,the following steps were carried out:obtaining field information with Drone equipment and using photogrammetric processes the topography of the study area was obtained,identification of unstable areas,trajectories,traces of the previously occurred landslides and five geomechanical stations.The specific weight of eight rock samples in the laboratory of the National University of Huancavelica was also calculated,which served to obtain the weight of the large-scale rock blocks.In addition,the normal and tangential restitution coefficients were calibrated,that is,field trials.Once the data were obtained,modeling was carried out by applying the Rocfall software,whose results of ten trajectories were:final distance reached,bounce height,kinetic energy and translational speed.With these values,risk maps have been prepared,taking into account the areas of housing vulnerability in the city of Huancavelica.Finally,it is proposed to mitigate these risks of rockfall,with dynamic barriers,which is important for the security of housing in the analysis sectors. | Ivan Ayala Bizarro Victor Paitan Sedano Edman Ventura Sullca Marco Lopez Barrantes Hugo Lujan Jeri Abdon Olivera Quintanilla Jorge Ortega Vargas Carlos Gaspar Paco | 2019 | Journal of Environmental Science and Engineering(A)2019，8，5： | 0 |
| 11 | Performance between the Hydraulic Gradient Method and the Perturbation Method for the Analysis of Water Supply Networks显示文摘The HGM(Hydraulic Gradient Method),it is used in most of the current commercial software,such as EPANET,WaterCAD,MikeNet,among others,the same that corresponds to an iterative method that depends on initial estimated parameters and programming structures that ensure convergence to obtain results with the highest precision,in addition to this the method makes use of non-linear equation systems.Likewise,the execution time for large extensions of water distribution networks is considerably high.On the other hand,the PM(Perturbation Method),is a new direct solution method,which makes use of principles of quantum mechanics to transform nonlinear equations into simpler linear systems.Obtaining a simple and robust optimization method that only requires simple and direct mathematical processes.Using the MathCad and Python programming languages as a verification tool,multiple tests were carried out,the results for the hydraulic parameters showing that the flow rates and pressures obtained by the HGM and the PM are extremely similar,in the same way the execution time(time run)have been 77.09%favorable to the PM.In other words,the PM presents efficiency to estimate the hydraulic characteristics such as the pressures at the nodes and the velocities in the pipes of the drinking water distribution networks. | Iván Ayala Bizarro Elviz Quispe García Marco Lopez Barrantes Freddy Marrero Saucedo Omar CaballeroSanchez Hugo Lujan Jeri Carlos Gaspar Paco Jorge Ortega Vargas | 2020 | Journal of Environmental Science and Engineering(A)2020，9，6： | 0 |
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