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| 1 | The next detectors for gravitational wave astronomy显示文摘This paper focuses on the next detectors for gravitational wave astronomy which will be required after the current ground based detectors have completed their initial observations, and probably achieved the first direct detection of gravitational waves. The next detectors will need to have greater sensitivity, while also enabling the world array of detectors to have improved angular resolution to allow localisation of signal sources. Sect. 1 of this paper begins by reviewing proposals for the next ground based detectors,and presents an analysis of the sensitivity of an 8 km armlength detector, which is proposed as a safe and cost-effective means to attain a 4-fold improvement in sensitivity. The scientific benefits of creating a pair of such detectors in China and Australia is emphasised. Sect. 2 of this paper discusses the high performance suspension systems for test masses that will be an essential component for future detectors, while sect. 3 discusses solutions to the problem of Newtonian noise which arise from fluctuations in gravity gradient forces acting on test masses. Such gravitational perturbations cannot be shielded, and set limits to low frequency sensitivity unless measured and suppressed. Sects. 4 and 5 address critical operational technologies that will be ongoing issues in future detectors. Sect. 4 addresses the design of thermal compensation systems needed in all high optical power interferometers operating at room temperature. Parametric instability control is addressed in sect. 5. Only recently proven to occur in Advanced LIGO, parametric instability phenomenon brings both risks and opportunities for future detectors. The path to future enhancements of detectors will come from quantum measurement technologies. Sect. 6 focuses on the use of optomechanical devices for obtaining enhanced sensitivity, while sect. 7 reviews a range of quantum measurement options. | BLAIR David JU Li ZHAO ChunNong WEN LinQing MIAO HaiXing CAI RongGen GAO JiangRui LIN XueChun LIU Dong WU Ling-An ZHU ZongHong HAMMOND Giles PAIK Ho Jung FAFONE Viviana ROCCHI Alessio BLAIR Carl MA YiQiu QIN JiaYi PAGE Michael | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，12： | 3 |
| 2 | Impact of Bt Cotton in China显示文摘 | Carl Pray D Ma Jikun Huang Fangbin Qiao | 2001 | World Development2001，，5： | 1 |
| 3 | Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle显示文摘 | Thornton C Snowden MA Carling D | 1998 | J Biol Chem1998，273，12： | 1 |
| 4 | Association of HIV, hepatitis C virus and liver fibrosis severity with interleukin-6 and C-reactive protein levels显示文摘 | Shailja Shah Yifei Ma Rebecca Scherzer Greg Huhn Audrey L. French Michael Plankey Marion G. Peters Carl Grunfeld Phyllis C. Tien | 2015 | AIDS2015，，11： | 1 |
| 5 | Expression of the uterine Mx protein in cyclic and pregnant cows,gilts,and mares显示文摘 | Hicks BA Etter SJ Carnahan KG Joyce MM Assiri AA Carling SJ Kodali K Johnson GA Hansen TR Mirando MA Woods GL Vandervall DK Ott TL | | 0，，06： | 1 |
| 6 | Consecutive series of patients with laryngeal carcinoma treated by primary irradiation 显示文摘 | Greisen O Carl J Pedersen MA | 1997 | Acta Oncol1997，36，： | 1 |
| 7 | Impacts of Bt Cotton in China显示文摘 | CARL MA Danmeng HUANG Jikun QIAO Fangbin | 2001 | World Development2001，，29： | 1 |
| 8 | Impact of Bt Cotton in China显示文摘 | Carl Pray D Ma Jikun Huang Fangbin Qiao | 2001 | World Development2001，，5： | 1 |
| 9 | Sepsis from the gut: the enteric habitat of bacteria that cause late-on- set neonatal bloodstream infections 显示文摘 | Carl MA Ndao IM Springman AC | 2014 | Clin Infect Dis2014，58，9： | 1 |
| 10 | Sepsis from the gut:the enteric habitat of bacteria that cause late-onset neonatal bloodstream infections显示文摘 | Carl MA Ndao IM Springman AC | 2014 | Clin Infect Dis2014，58，9： | 1 |
| 11 | A comparison of crop data measured by two commercial sensors for variable-rate nitrogen application显示文摘 | Nicolas Tremblay Zhijie Wang Bao-Luo Ma Carl Belec Philippe Vigneault | 2009 | Precision Agriculture2009，，2： | 1 |
| 12 | Current dosing of low - mo- lecular - weight heparins does not reflect licensed product labels : an in-ternational survey 显示文摘 | Barras MA Kirkpatrick Carl MJ Green B | 2010 | Br J Clin Pharmacol2010，69，5： | 1 |
| 13 | Corneal healing after uncomplicated LASIK and its relationship to refractive changes: A six-month prospective confocal study显示文摘 | Avni MA Carl JS Sherif E | 2004 | Invest Ophthalmol Vis Sci2004，45，： | 1 |
| 14 | Alveolar Permeability Enhancement by Oleic Acid and Related Fatty Acids: Evidence for a Calcium-Dependent Mechanism显示文摘 | Li Ying Wang Joseph K. H. Ma Wei Fang Pan David Toledo-Velasquez Carl J. Malanga Yongyut Rojanasakul | 1994 | Pharmaceutical Research1994，，4： | 1 |
| 15 | Corneal healing after uncomplicated LASIK and its relationship to refractive changes:A six-month prospect ire cortfocal study显示文摘 | Avni MA Carl JS Sherif E | 2004 | Invest Ophthalmol Vis Sci2004，45，4： | 1 |
| 16 | Impacts of Bt Cotton in China 显示文摘 | PRAY CARL MA Danmeng HUANG Jikun QIAO Fangbin | 2001 | World Development2001，，29： | 1 |
| 17 | Integrin CD11 c/CD18 a-chain phosphorylation is functionally important 显示文摘 | Liisa M Uotila MA Carl G | 2013 | Bio Chem2013，288，33： | 1 |
| 18 | Prudently conduct the engineering and synthesis of the SARS-CoV-2 virus显示文摘In response to the outbreak of COVID-19 that has been sweeping the world,scientists reconstructed the SARSCoV-2 rapidly using a synthetic genomics platform,in order to accelerate therapeutics and vaccine development.However,given the dual-use nature of this technology,there exists a high biosecurity risk.This paper points out the potential risks of the engineering SARS-CoV-2 virus and puts forward 6 questions to this work.The authors emphasize that the two basic values of safety/security and intellectual freedom of research must be considered evenly.From the perspective of responsible development of biotechnology,this paper calls for a careful assessment to the risks of the technology,replacing risky technologies with safe ones.The risks of publication also need to be strictly assessed.The authors believe,in addition to enhancing the“self-government”and self-discipline of scientists and scientific communities,government supervision must be reinforced,laws and regulations should be improved,and global regulation framework ought to be constructed. | Peng Gao Shiwen Ma Daru Lu Carl Mitcham Yijia Jing Guoyu Wang | 2020 | Synthetic and Systems Biotechnology2020，5，2： | 0 |
| 19 | 肌电图监测面神经功能用于预测标准麻醉深度患者的体动反应显示文摘背景面神经(facialnerve,FN)监测已成为颅面部手术、中耳手术以及颅底手术的标准监护手段,以减少医源性损伤,进行面神经定位,并预测术后神经功能。以往的研究也表明面神经肌电图监测(facialnerve electromyography,FNEMG)具有评估麻醉深度和预测患者体动的临床价值。本研究旨在探讨脑电双频指数(bispectral index,BIS)和FNEMG在两种不同的麻醉方式中,是否能用于预测颅骨手术患者的术中体动。方法采用单盲、随机、对照的临床试验方法,将FNEMG监测和BIS监测用于特殊颅面部手术和颅骨手术的全麻患者,评价这两种监测手段预测术中患者体动的相关性。另外采用异丙酚联合瑞芬太尼的全凭静脉麻醉(total IV anesthetic,TIVA)与地氟烷吸入麻醉进行比较,确定何种麻醉方式既能够提供最佳的充分麻醉状态,也能够预防需要FNEMG监测的非肌松患者术中运动。结果TIVA组血流动力学状态更好。两组间BIS值无显著性差异,而TIVA组FNEMG活性更低。地氟烷组出现运动的患者多于TTVA组,10例运动患者中有8例存在显著FNEMG活性,FNEMG对术中可见运动的阳性预测价值为38%,阴性预测值为95%。FNEMG表现活性的运动患者与无运动患者相比,血流动力学、BIS值与基础值相比均无显著变化。结论本研究表明FNEMG可能成为预测颅面部手术和颅底手术患者术中运动的有效监测。但是,BIS监测不能充分预测这类患者的运动。DES组更常见血流动力学变化和FNEMG活性,而TTVA更有效的防止患者运动,可调整剂量为临床操作提供稳定的状态。FNEMG是辅助预测并阻止颅面部手术和颅底手术患者运动的一种有效的临床工具。 | W. Scott Jellish John P. Leonetti Carl M. Buoy, BA James M. Sincacore I(ristina J. Sawicki BSN, Micheal P. Ma&en 房丽丽(译) 严敏(校) | 2012 | 麻醉与镇痛2012，8，2： | 0 |
| 20 | In vitro assessment of the effect of microencapsulation techniques on the stability,bioaccessibility and bioavailability of mulberry leaf bioactive compounds显示文摘Mulberry(Morus alba L.)leaf extract is well-known for its health-promoting features.However,food processing conditions affect its bioactive profile,which could be limited by encapsulation.Nevertheless,assessing the impact of encapsulating techniques on the digestibility of embedded biocompounds requires further knowledge.Hence,the aimed of this study was to assess the effects of carrier materials and drying techniques on(i)bioaccessibility and bioavailability indexes,(ii)stability of nutraceuticals,and(iii)changes in antioxidant activities of mulberry leaf extract powder by using an in vitro oral-gastrointestinal digestion.Digestion was performed out at 37°C in darkness by shaking encapsulated extract with human saliva during 2 min,followed by 2 h of incubation with a pepsin-HCl mixture,then mixed for 2 h with bile salts and pancreatin.After digestion the samples were acidified and HPLC assayed.A significant(p<0.05)decrease in nutraceuticals content was noted during the intestinal phase with more reduction in gamma-aminobutyric acid(34.91–51.14%)compared to that of flavonols(16.58–28.90%),1-deoxynojirimycin(17.56–20.42%)and phenolic acids(0.53–0.67%)in the gastric digesta.Although encapsulation was observed to enhance the bioaccessibility,negative effects were found in terms of the bioefficiency and bioavailability.Furthermore,encapsulation techniques mostly affected the ion reducing capacity than the radical scavenging capacity.The outcomes suggested that carriers had a major effect on the digestibility and antioxidative activity,whilst the drying techniques mostly affect the bioaccessibility and bioavailability of the flavonols. | William Tchabo Giscard Kuate Kaptso Guillaume Legrand Ngolong Ngea Kenuo Wang Guifeng Bao Yongkun Ma Xiangyang Wang Carl Moses Mbofung | 2022 | Food Bioscience2022，47，3： | 0 |
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