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| 1 | Self-assembled multifunctional DNA nanoflowers for the circumvention of multidrug resistance in targeted anticancer drug delivery显示文摘癌症化疗被它的副作用和 multidrug 抵抗(MDR ) 限制了。因此,指向了能围绕 MDR 的药交货系统被需要。这里,我们向 chemosensitive 和在白血病和乳癌房间模型围绕了 MDR 的 MDR 癌症房间为指向的药交货汇报多功能的 DNA nanoflowers (NF ) 。NF 经由卷圆复制, NF 为特定的癌症房间识别,为 bioimaging 的 fluorophores,和 doxorubicin (纪录影片) 用 aptamers 在期间被合并产生的 DNA 和镁焦磷酸盐的潜在的一起沉淀是自我装配的为药交货的有约束力的 DNA。NF 尺寸是悦耳的(在直径击倒 nm 到 200 ) ,并且浓密地包装的药绑定主题和多孔的 intrastructures 赋予 NF 以一个高装载药的能力(71.4% , wt/wt ) 。尽管 Doxloaded NF (NF 纪录影片) 在生理的 pH 是稳定的,药版本在酸或基本的条件下面被便于。NF 交付纪录影片进目标 chemosensitive 和 MDR 癌症房间,阻止药流出并且提高在 MDR 房间的药保留。NF 纪录影片在两个目标 chemosensitive 房间和 MDR 房间,然而并非在 nontarget 房间导致有势力 cytotoxicity,并发地因此围绕 MDR 并且减少副作用。总的来说,这些 NF 为在指向的癌症治疗围绕 MDR 正在答应工具。 | Lei Mei Guizhi Zhu Liping Qiu Cuichen Wu Huapei Chen Hao Liang Sena Cansiz Yifan Lv Xiaobing Zhang Weihong Tan | 2015 | Nano Research2015，8，11： | 8 |
| 2 | Surgical treatment of laryngeal tumors with subglottic extension and tracheal tumors with composite nasal septal cartilage graft:technique and outcome显示文摘 | CANSIZ H YENER M BOZKURT A K | 2008 | Auris Nasus Larynx2008，35，： | 1 |
| 3 | Chitosan coating minimises eggshell breakage and improves egg quality显示文摘 | Caner C Cansiz O | | Journal of the Science of Food and Agriculture0，，： | 1 |
| 4 | Vertical and Lateral Forces Be- tween a Permanent and a High - Temperature Supercon- ductor显示文摘 | Hull John R Cansiz A | 1999 | Journal of Applied Physics1999，86，11： | 1 |
| 5 | A superconducting thrust- bearing system for an energy storage flywheel显示文摘 | Coombs T A Cansiz A Campbell A M | 2002 | Supercond Sci Teehnol2002，，15： | 1 |
| 6 | Surgical treatment of laryngeal tumors with subglottic extension and tracheal tumors with composite nasal septal cartilage graft:Technique and outcome显示文摘 | Cansiz H Yener M Bozkurt A K | | 0，，03： | 1 |
| 7 | 3-Aryl-5-furylpyrazolines and Their Biological Activities显示文摘 | Cetin A Cansiz A Digrak M | | 0，，4： | 1 |
| 8 | Three -wall orbital decompression superiority to 2 - wall orbital decompression in thyroid - associated ophthalmopathy 显示文摘 | Cansiz H Yilmaz S Karaman E | 2006 | J Oral Maxillofac Surg2006，64，5： | 1 |
| 9 | A study of prognostic factors in sudden heating loss 显示文摘 | Mamak A Yilmaz S Cansiz H | 2005 | Ear Nose Throat J2005，84，10： | 1 |
| 10 | Chitosan coatingminimises eggshell breakage and improves egg quality显示文摘 | CANER C CANSIZ O | 2008 | Sci Food Agric2008，88，： | 1 |
| 11 | Chitosan coating minimises eggshell breakage and improves egg quality 显示文摘 | Caner C Cansiz O | 2008 | Journal of the Science ofFood and Agriculture2008，，61： | 1 |
| 12 | Surgical approaches to juvenile nasopharyngeal angiofibroma 显示文摘 | CANSIZ H GUVENC M G SEKERCIOGLU N | 2006 | J Craniomaxillofac Surg2006，34，1： | 1 |
| 13 | Laryngotracheal reconstruction with a muscle-pedicle hyoid bone flap:a series of 23 patients显示文摘 | Cansiz H Yener HM Sekercioglu N Günes M | | 0，，： | 1 |
| 14 | An evershed type superconducting flywheel bearing显示文摘 | CANSIZ A CAMPBELL A M COOMBS T A | 2003 | Physica C2003，390，： | 1 |
| 15 | A study of prognostic factors in sudden hearing loss 显示文摘 | MAMAK A YILMAZ S CANSIZ H | 2005 | Ear Nose Throat2005，84，： | 1 |
| 16 | A study of prognostic factors in sudden hearing loss显示文摘 | Mamak A Yilmaz S Cansiz H | 2005 | Ear Nose Throat2005，84，10： | 1 |
| 17 | Improvements to G4 ( RW ) strong-post round-wood, W-beam guardrail system 显示文摘 | Atahan A O ASCE M Cansiz O F | 2005 | Journal of transportation engineering2005，，： | 1 |
| 18 | Vertical and lateral forces betweena permanent magnet and a high-temperature superconductor显示文摘 | Hull J R Cansiz A | 1999 | Journal of Applied Physics1999，86，11： | 1 |
| 19 | A case of increased intracranial pressure after unilateral modified radical neck dissection 显示文摘 | Karaman E Saritzali G Cansiz H | 2009 | Am J Otolaryngol2009，30，4： | 1 |
| 20 | An evershed type superconducting flywheel bearing 显示文摘 | Cansiz A Campbell A M Coombs T A | 2003 | Physica C2003，390，： | 1 |
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