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| 1 | Risk factors associated with the development of ischemic colitis显示文摘AIM:To ascertain the role of cardiovascular risk factors,cardiovascular diseases,standard treatments and other diseases in the development of ischemic colitis(IC).METHODS:A retrospective,case-control study was designed,using matched data and covering 161 incident cases of IC who required admission to our hospital from 1998 through 2003.IC was diagnosed on the basis of endoscopic findings and diagnostic or compatible his-tology.Controls were randomly chosen from a cohort of patients who were admitted in the same period and required a colonoscopy,excluding those with diagnosis of colitis.Cases were matched with controls(ratio 1:2),by age and sex.A conditional logistic regression was performed.RESULTS:A total of 483 patients(161 cases,322 con-trols)were included;mean age 75.67±10.03 years,55.9%women.The principal indications for colonos-copy in the control group were lower gastrointestinal hemorrhage(35.4%),anemia(33.9%),abdominal pain(19.9%)and diarrhea(9.6%).The endoscopic findings in this group were hemorrhoids(25.5%),diverticular disease(30.4%),polyps(19.9%)and colorectal cancer(10.2%).The following variables were associated with IC in the univariate analysis:arterial hypertension(P= 0.033);dyslipidemia(P<0.001);diabetes mellitus(P =0.025);peripheral arterial disease(P=0.004);heart failure(P=0.026);treatment with hypotensive drugs(P=0.023);angiotensin-converting enzyme inhibitors;(P=0.018);calcium channel antagonists(P=0.028);and acetylsalicylic acid(ASA)(P<0.001).Finally,the following variables were independently associated with the development of IC:diabetes mellitus[odds ratio(OR)1.76,95%confidence interval(CI):1.001-3.077,P=0.046];dyslipidemia(OR 2.12,95%CI:1.26-3.57,P=0.004);heart failure(OR 3.17,95%CI:1.31-7.68,P=0.01);peripheral arterial disease(OR 4.1,95%CI:1.32-12.72,P=0.015);treatment with digoxin(digitalis)(OR 0.27,95%CI:0.084-0.857,P=0.026);and ASA(OR 1.97,95%CI:1.16-3.36,P=0.012).CONCLUSION:The development of an episode of IC was independently associated with diabetes,dyslipid-emia,presence of heart failure,peripheral arterial dis-ease and treatment with digoxin or ASA. | Joaquín Cubiella Fernández Luisa Núez Calvo Elvira González Vázquez Maria Jesús García García Maria Teresa Alves Pérez Isabel Martínez Silva Javier Fernández Seara | 2010 | World Journal of Gastroenterology2010，16，36： | 27 |
| 2 | The importance of avoiding unnecessary right ventricular pacing in clinical practice显示文摘Symptomatic bradycardia is effectively treated with the implantation of a cardiac pacemaker. Although a highly successful therapy, during recent years there has been a focus on the negative effects associated with longterm pacing of the apex of the right ventricle(RV). It has been shown in both experimental and clinical studies that RV pacing leads to ventricular dyssynchrony, similar to that of left bundle branch block, with subsequent detrimental effects on cardiac structure and function, and in some cases adverse clinical outcomes such as atrial fibrillation, heart failure and death. There is substantial evidence that patients with reduced left ventricular function(LVEF) are at particular high risk of suffering the detrimental clinical effects of long-term RV pacing. The evidence is, however, incomplete, coming largely from subanalyses of pacemaker and implantable cardiac defibrillator studies. In this group of patients with reduced LVEF and an expected high amount of RV pacing, biventricular pacing(cardiac resynchronization therapy) devices can prevent the negative effects of RV pacing and reduce ventricular dyssynchrony. Therefore, cardiac resynchronization therapy has emerged as an attractive option with promising results and more clinical studies are underway. Furthermore, specific pacemaker algorithms, which minimize RV pacing, can also reduce the negative effects of RV stimulation on cardiac function and may prevent clinical deterioration. | Finn Akerstrm Miguel A Arias Marta Pachón Jesús Jiménez-López Alberto Puchol Justo Juliá-Calvo | 2013 | World Journal of Cardiology2013，5，11： | 3 |
| 3 | Circulating levels of GDF15, MMP7 and miR-200c as a poor prognostic signature in gastric cancer显示文摘 | Moisé s Blanco-Calvo Nuria Tarrí o Margarita Reboredo Mar Haz-Conde Jorge Garcí a Marí a Quindó s Angé lica Figueroa Luis Antó n-Aparicio Lourdes Calvo Manuel Valladares-Ayerbes | 2014 | Future Oncol2014，，7： | 2 |
| 4 | 在经历 transcatheter 的病人的 atrial 纤维性颤动的临床、预示的含意大动脉的阀门培植显示文摘 AIM: To study a cohort of consecutive patients under-going transcatheter aortic valve implantation (TAVI) and compare the outcomes of atrial fibrillation (AF) patients vs patients in sinus rhythm (SR). METHODS: All consecutive patients undergoing TAVI in our hospital were included. The AF group comprised patients in AF at the time of TAVI or with history of AF, and were compared with the SR group. Procedural, echocardiographic and follow-up variables were compared. Likewise, the CHA 2 DS 2-VASC stroke risk score and HAS-BLED bleeding risk score and antithrombotic treatment at discharge in AF patients were compared with that in SR patients. RESULTS: From a total of 34 patients undergoing TAVI, 17 (50%) were allocated to the AF group, of whom 15 (88%) were under chronic oral anticoagulation. Patients in the AF group were similar to those in the SR group except for a trend (P = 0.07) for a higher logistic EuroSCORE (28% vs 19%), and a higher prevalence of hypertension (82% vs 53%) and chronic renal failure (17% vs 0%). Risk of both stroke and bleeding was high in the AF group (mean CHA 2 DS 2-VASC 4.3, mean HAS-BLED 2.9). In the AF group, treatment at discharge included chronic oral anticoagulation in all except one case, and in association with an antiplatelet drug in 57% of patients. During a mean follow-up of 11 mo (maximum 32), there were only two strokes, none of them during the peri-procedural period: one in the AF group at 30 mo and one in the SR group at 3 mo. There were no statistical differences in procedural success, and clinical outcome (survival at 1 year 81% vs 74% in AF and SR groups, respectively, P = NS). CONCLUSION: Patients in AF undergoing TAVI show a trend to a higher surgical risk. However, in our cohort, patients in AF did not have a higher stroke rate compared to the SR group, and the prognosis was similar in both groups. | Pablo Salinas Raúl Moreno Luis Calvo Santiago Jiménez-Valero Guillermo Galeote Angel Sánchez-Recalde Teresa López-Fernández Sergio Garcia-Blas Diego Iglesias Luis Riera Isidro Moreno-Gómez Jose María Mesa Ignacio Plaza Rocio Ayala Rosa Gonzalez José-Luis López-Sendón | 2012 | World Journal of Cardiology2012，4，1： | 2 |
| 5 | Maintenance treatment with Pegylated liposomal doxorubicin versus observation following induction chemotherapy for metastatic breast cancer: GEICAM 2001-01 study显示文摘 | Emilio Alba Manuel Ruiz-Borrego Mireia Margelí álvaro Rodríguez-Lescure Pedro Sánchez-Rovira Amparo Ruiz Jose Ramón Mel-Lorenzo Manuel Ramos-Vázquez Nuria Ribelles Elisa Calvo Antonio Casado Antonia Márquez David Vicente José Angel García-Sáenz Miguel Mar | 2010 | Breast Cancer Research and Treatment2010，，1： | 2 |
| 6 | Influence of formula- tion on propofol pharmacokineties and pharmacodynam ics in anesthetized patients显示文摘 | Calvo R Telletxea S Leal N et a l | 2004 | Acta Anaesthesiol Scand2004，48，8： | 1 |
| 7 | Impulsive noise measurement and characterization in a UHF digital TV channel显示文摘 | Manuel García Sánchez Leandro de Haro Miguel Calvo Ramón | 1999 | IEEE Transactions on Electromagnetic Compatibility1999，41，2： | 1 |
| 8 | Hedgehog signalling as a target in cancer stem cells显示文摘 | Medina V Calvo MB Díaz-Prado S | 2009 | Clin Transl Oncol2009，11，4： | 1 |
| 9 | Metabolic monitoring of postischemic myocardium during intermittent warm-blood cardioplegic administration显示文摘 | Borowski A Kurt M Calvo S | 2010 | Tex Heart Inst J2010，37，2： | 1 |
| 10 | Characterization of a new experimental model of osteoporosis in rabbits显示文摘 | Castaneda S Calvo E Largo R | 2008 | J Bone Miner Metab2008，26，1： | 1 |
| 11 | The genome sequence of the filamentous fungus Neurospora显示文摘 | Galagan J E Calvo S E Borkovich K A | 2003 | Nature2003，422，6934： | 1 |
| 12 | The genuine sequence of the filamentous fungus Neurospora crassa 显示文摘 | Galagan J E Calvo S E Borkovich K A | 2003 | Nature2003，422，： | 1 |
| 13 | Bone mineral mea- surements of subchondral and trabecular bone in healthy and osteoporotic rabbits 显示文摘 | Castaneda S Largo R Calvo E | 2006 | Skeletal Radiol2006，35，1： | 1 |
| 14 | Does the presence of hepatitis virus B and C influence the evolution of diffuse large B-cell lymphoma?显示文摘 | Judit Rubio Fernando Franco Antonio Sá nchez Blanca Cantos Miriam Mé ndez Virginia Calvo Constanza Maximiano David Perez Isabel Millá n Margarita Sá nchez-Beato Mariano Provencio | 2015 | Leukemia & Lymphoma2015，，6： | 1 |
| 15 | Adenovirus-mediated endostatin delivery results in inhibition of mammary gland tumor growth in C3 (1)/SV40 T-antigen transgene mice显示文摘 | Calvo A Feldman A L Libutti S K | 2002 | Cancer Res2002，62，14： | 1 |
| 16 | Molecular basis and clinical applica- tion of biological markers of bone turnover 显示文摘 | Calvo M S Eyre D R Caren M G | 1996 | Endocr Rev1996，17，4： | 1 |
| 17 | Special stature of the formation of the diffusion banded joints between copper and aluminium 显示文摘 | Calvo S A Urena A | 1988 | Journal of Materials Science1988，23，8： | 1 |
| 18 | The genome sequence of the filamentous fungus Neurospora crassa显示文摘 | Galagan J E Calvo S E Borkovich K A | 2003 | Nature2003，442，： | 1 |
| 19 | Vitamin D fortification in the United States and Canada:current status and data needs显示文摘 | CALVO M S WHITING S J BARTON C N | 2004 | American Journal of Clinical Nutrition2004，80，6： | 1 |
| 20 | Detecting Naturalistic Expressions of Nonbasic Affect Using Physiological Signals 显示文摘 | ALZOUBI O D'MELLO S K CALVO R A | 2010 | IEEE Transactions on Affecitive Computing2010，1，2： | 1 |
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