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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Effect of Cold-Water Immersion on Skeletal Muscle Contractile Properties in Soccer Players显示文摘 | Juan Manuel García-Manso Darío Rodríguez-Matoso David Rodríguez-Ruiz Samuel Sarmiento Yves de Saa Javier Calderón | 2011 | American Journal of Physical Medicine & Rehabilitation2011，，5： | 2 |
| 3 | The effect of propolis and its components on eicosanoid production during the inflammatory response 显示文摘 | Mirzoeva O K Calder P C | 1996 | Prostaglandins Leukotrienes Essent Fatty Acids1996，55，6： | 1 |
| 4 | On a problem of Mihlim显示文摘 | CALDER(O)N A P ZYGMUND A | 1995 | Trans Amer Math Soc1995，78，2： | 1 |
| 5 | On singular integral with variable kernels显示文摘 | CALDER(O)N A P ZYGMUND A | 1978 | Appl Analysis1978，7，2： | 1 |
| 6 | Microstructure evolution in magnetorheological suspensions governed by Mason number显示文摘 | Melle S Calderón O G Rubio M A | 2003 | Phys Rev2003，68，04： | 1 |
| 7 | Somicrobial commumity composition and land use history icultivated and grassland ecosystems of coastal California显示文摘 | STEENWERTH K L JACKSON L E CALDER(O)N F J | 2002 | Soil Biology& Biochemistry2002，34，： | 1 |
| 8 | Parabolic maximal functions associated with a distribution显示文摘 | CALDER(o)N A P TORKINSKY A | | 0，，： | 1 |
| 9 | Parabolic maximal functions associated with a distribution Ⅱ显示文摘 | CALDER(O)N A P TORKINSKY A | | 0，，： | 1 |
| 10 | EBM in primary care: a qualitative multicenter 显示文摘 | Calder o n C Sola I Rotaeche R | 2011 | BMC Faro Pract2011，12，9： | 1 |
| 11 | Role of reduced exogenous organic compounds in the physiology of the blue-green bacteria(algae): photoheterotrophic growth of a 'heterotrophic' blue-green bacterium 显示文摘 | Ingram L O Calder J A Vanbaalen C | 1973 | Bacteriology1973，114，2： | 1 |
| 12 | MnxZn1-x-Fe2-yRyO4 (R=Gd,Eu) ferrite nanocrystals for magnetocaloric applications显示文摘 | Calderón-Ortiz E Perales-Perez O Voyles P | 2009 | Microelectron J2009，40，45： | 1 |
| 13 | Epidural hematoma显示文摘 | Scheibl A Calder(o)n EM Borau MJ | | 0，，2： | 1 |
| 14 | Dynamic behavior of Arabidopsis elF4A-Ⅲ, putative core protein of exon junction complex: fast relocation to nucleolus and splicing speckles under hypoxia显示文摘 | Koroleva O A Calder G Pendle A F | 2009 | Plant Cell2009，21，5： | 1 |
| 15 | Aantegrade intramedullary fixationofdisplaced fifthmetacarpal fractures显示文摘 | Calder JD O'Leary S Evans SC | 2000 | Injury2000，31，： | 1 |
| 16 | Early phenotypic and genotypic alterations in submandibular gland oncogenesis in rats显示文摘 | Brunotto M Malberti A Zarate AM Barra JL Calderón O Pinas E Plavnik L Crosa M | 2006 | Acta Odontol Latinoam2006，19，1： | 1 |
| 17 | The use of Magallanic peat as non-conventional sorbent for EDTA removal from wastewater显示文摘 | CALDER(O)N M MORAGA C LEAL J | 2008 | Bioresource Technology2008，99，17： | 1 |
| 18 | Effects of diabetes on oxidative and nitrosative stress in kidney mitochondria from aged rats显示文摘 | Rocío V. Pérez-Gallardo Ruth Noriega-Cisneros Edgar Esquivel-Gutiérrez Elizabeth Calderón-Cortés Christian Cortés-Rojo Salvador Manzo-Avalos Jesús Campos-García Rafael Salgado-Garciglia Rocío Montoya-Pérez Istvan Boldogh Alfredo Saavedra-Molina | 2014 | Journal of Bioenergetics and Biomembranes2014，，6： | 1 |
| 19 | Trade intensity and business cycle synchronization:Are developing countries any different显示文摘 | Calder(o)n | | 0，，71： | 1 |
| 20 | Aantegrade intramedullary fixtion of displaced fifth metacarpal fractures显示文摘 | Calder JD O' Leary S Evans SC | 2000 | Injury2000，31，： | 1 |
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