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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Modulation of matrix metalloproteinase-9 activity by hyaluronan is dependent on NF-kappaB activity in lymphoma cell lines with dissimilar invasive behavior显示文摘 | Alaniz L Garcia M Cabrera P | 2004 | Biochem Biophys Res Commun2004，324，2： | 1 |
| 3 | Effects of drying and rewetting on carbon and nitrogen mineralization in soils and incorporated residues显示文摘 | Kruse J S Kissel D E Cabrera M L | 2004 | Nutr Cycl Agroeco- sys2004，69，： | 1 |
| 4 | Tuning the stator resistance of induction motors using the artificial neural network 显示文摘 | Cabrera L A Elbuluk M E Husain I | 1997 | IEEE Trans on PE1997，12，5： | 1 |
| 5 | The essential oil of Senecio graveolens(Compositae) : Chemical composition and antimicrobial activity tests 显示文摘 | PEREZ C AGNESE A M CABRERA J L | 1999 | Journal of Ethnopharmacology1999，66，2： | 1 |
| 6 | Ammonia volatilization from urea, ammonium sulfate and NutraSweet sludge in bare and straw-cov- ered soils显示文摘 | Shahandeh H Cabrera M L Sumner M E | 1992 | Communications in Soil Science and Plant A nolysis1992，23，78： | 1 |
| 7 | Aggregate-protected and unprotected organic matter pools in conventional and no-tillage soils 显示文摘 | BEARE M H HENDRIX P F CABRERA M L | 1994 | Soil Science Society of America Journal1994，58，3： | 1 |
| 8 | Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle 显示文摘 | JI L L GOMEZ CABRERA M C STEINHAFEL N | 2004 | FASEB J2004，18，13： | 1 |
| 9 | Learning technique to train neural networks as a state selector for inverter-fed induction machines using direct torque control 显示文摘 | Cabrera L A Elbuluk M E Zinger D S | 1997 | IEEE Trans on PE1997，12，5： | 1 |
| 10 | Aggregate-protected and unprotected organic matter pools in conventional-tillage and no-tillage soils显示文摘 | Beate M H Cabrera M L Hendrix P F | 1994 | Soil Sci Soc Am J1994，58，： | 1 |
| 11 | Influence of growth temperature on cryotolerance and lipid composition of lactobacillus acidophilus显示文摘 | FERNANDEZ MURGA M L CABRERA G M FONT DE VALDEZ G | 2000 | Journal of Applied Microbiology2000，88，2： | 1 |
| 12 | Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly (dimethylsiloxane) devices 显示文摘 | HEO Y S CABRERA L M SONG J W | 2007 | Anal Chem2007，79，3： | 1 |
| 13 | EBSD study of purity effects during hot working in austenitic stainless steels显示文摘 | Wahabi E I Gavara M Cabrera L | 2005 | Mater Sci and Eng A2005，393，： | 1 |
| 14 | Agricultural use of three (sugar-beet) vinasse composts: effect on crops and chemical properties of a Cambisol soil in the Guadalquivir river valley (SW Spain)显示文摘 | Engracia Madejón Rafael López José M Murillo Francisco Cabrera | 2001 | Agriculture Ecosystems and Environment2001，，1： | 1 |
| 15 | Aggregate-protected and unprotected organic matter pools in conventional and no-tillage soils显示文摘 | BEAR M H CABRERA M L HENDRIX P F | 1994 | Soil Science Society of America Journal1994，，58： | 1 |
| 16 | Alkaline persulfate oxida- tion for determining total nitrogen in microbial biomass extracts 显示文摘 | Cabrera M L Beare M H | 1993 | Soil Science Society of America Journal1993，57，4： | 1 |
| 17 | Aboveground and be- lowground competition between intercropped cabbage and young Eucalyptus torelliana显示文摘 | Nissen T M Midmore D J Cabrera M L | 1999 | Agroforestry Systems1999，46，1： | 1 |
| 18 | Hot deformation of duplex stainless steels 显示文摘 | Cabrera J M Mateo A Llanes L | 2003 | Journal of Materials Processing Technology2003，，： | 1 |
| 19 | Hot Delormation of Duplex Stainless Steels 显示文摘 | Cabrera J M Mateo A Llanes L | 2003 | Journal of Materials Processing Technology2003，143，144： | 1 |
| 20 | Reactions of ammonia and urea-hydrolysis products in soil显示文摘 | KISSEL D E CABRERA M L FERGUSON R B | 1988 | Soil Sci Soc Am1988，52，： | 1 |
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