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| 1 | Complex interactomes and post-translational modifications of the regulatory proteins HABP4 and SERBP1 suggest pleiotropic cellular functions显示文摘The 57 kDa antigen recognized by the Ki-1 antibody,is also known as intracellular hyaluronic acid binding protein 4 and shares 40.7%identity and 67.4%similarity with serpin mRNA binding protein 1,which is also named CGI-55,or plasminogen activator inhibitor type-1-RNA binding protein-1,indicating that they might be paralog proteins,possibly with similar or redundant functions in human cells.Through the identification of their protein interactomes,both regulatory proteins have been functionally implicated in transcriptional regulation,mRNA metabolism,specifically RNA splicing,the regulation of mRNA stability,especially,in the context of the progesterone hormone response,and the DNA damage response.Both proteins also show a complex pattern of post-translational modifications,involving Ser/Thr phosphorylation,mainly through protein kinase C,arginine methylation and SUMOylation,suggesting that their functions and locations are highly regulated.Furthermore,they show a highly dynamic cellular localization pattern with localizations in both the cytoplasm and nucleus as well as punctuated localizations in both granular cytoplasmic protein bodies,upon stress,and nuclear splicing speckles.Several reports in the literature show altered expressions of both regulatory proteins in a series of cancers as well as mutations in their genes that may contribute to tumorigenesis.This review highlights important aspects of the structure,interactome,post-translational modifications,sub-cellular localization and function of both regulatory proteins and further discusses their possible functions and their potential as tumor markers in different cancer settings. | Carolina Colleti Talita Diniz Melo-Hanchuk Flavia Regina Moraes da Silva Angela Saito Jorg Kobarg | 2019 | World Journal of Biological Chemistry2019，10，3： | 4 |
| 2 | Structural insights into substrate traffic and inhibition in acetylcholinesterase 显示文摘 | Colletier JP Fournier D Greenblatt HM | 2006 | EMBO J2006，25，： | 1 |
| 3 | The potential use of mixed fihns of pectin, chitosan and HPMC for bimodal drug release显示文摘 | MACLEOD G S COLLETY J H FELL J T | 1999 | J Controlled Release1999，58，3： | 1 |
| 4 | Chemotherapy with Preoperative Radiotherapy in Rectal Cancer 显示文摘 | BOSSET J F COLLETI'E L CALAIS G | 2006 | N Engl J Med2006，355，11： | 1 |
| 5 | Molecular basis for amyloid-beta poiymorphism显示文摘 | Colletier JP Laganowsky A Landau M | 2011 | Proc Natl Acad Sci USA2011，108，16： | 1 |
| 6 | Brain imaging of the cental execu- tive component of working memory 显示文摘 | COLLETI'E VAN L M | 2002 | Neurosci Biobehav- ioral Pev2002，26，2： | 1 |
| 7 | Molecular basis for amyloid-beta polymorphism显示文摘 | COLLETIER J P LAGANOWSKY A LANDAU M | 2011 | Proc Natl Acad Sci USA2011，108，16： | 1 |
| 8 | Energy resource potential of natural gas hydrates 显示文摘 | COLLETY T S | 2002 | AAPGBulletin2002，86，11： | 1 |
| 9 | Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases , mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis 显示文摘 | Carletti E Schopfer LM Colletier JP | 2011 | Chern Res Toxicol2011，24，6： | 1 |
| 10 | Adenoviral-mediated p53 transgene expression sensitizes both wild-type and null p53 prostate cancer in vitro to radiation显示文摘 | Colletier PJ Ashoori F Cowen D | 2000 | Int J Radiat Oncol Biol Phys2000，48，5： | 1 |
| 11 | The effect of feeding regimen on growth, food conversion ratio and size variation in juvenile dusky kob Argyrosomus japonicus ( Teleostei : Sciaenidae) 显示文摘 | KAISER H COLLETY P D VINE N G | 2011 | African Journal of Aquatic Science2011，36，1： | 1 |
| 12 | Postoperative radiation for squamous cell carcinoma metastatic to cervical lymph nodes from an unknown site: outcomes and patterns of failure显示文摘 | Colletier PJ Garden AS Morrison WH | 1998 | Head Neck1998，20，67： | 1 |
| 13 | Evidence of gadolinium distribution from the endolymphatic sac to the endolymphacit compartments of the human inner ear显示文摘 | Colleti V Mandala M Carner M | 2010 | Audiol Neurootol2010，15，： | 1 |
| 14 | Protein encapsulation in liposomes: efficiency depends on interactions between protein and phospholipid bilayer显示文摘 | COLLETIER J P CHAIZE B WINTERHALTER M | 2002 | BMC Biotechnol2002，2，： | 1 |
| 15 | Tumor necrosis factor up-regulates intercellular adhension modullar neutrophil-dependent lung and liver injury associated with hepatic ischemia reperfusion in the rat显示文摘 | COLLETI L M CORTIS A | 1998 | Shock1998，10，： | 1 |
| 16 | EZH2 expression is associated with high proliferation rate and ag- gressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast 显示文摘 | I M BACHMANN O J HALVORSEN K COLLETI' | 2006 | Clinical Oncology2006，24，： | 1 |
| 17 | The role of eytokine networks in the local liver injury following hepatic ischemia/reperfusion in the rat 显示文摘 | COLLETI L M KUNKEL S L WALZ A | 1996 | Hepatology1996，23，： | 1 |
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