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| 1 | Triglyceride levels and apolipoprotein E polymorphism in patients with acute pancreatitis显示文摘BACKGROUND:Hypertriglyceridemia is an unusual cause of acute pancreatitis and sometimes considered to be an epiphenomenon.This study aimed to investigate the clinical and analytical features and the APOE genotypes in patients with acute pancreatitis and severe hypertriglyceridemia.METHODS:We undertook a one-year,prospective study of patients with acute pancreatitis whose first laboratory analysis on admission to the emergency department included measurement of serum triglycerides.The APOE genotype was determined and the patients answered an established questionnaire within the first 24 hours concerning their alcohol consumption,the presence of co-morbidities and any medications being taken.The patients' progression,etiological diagnosis,hospital stay and clinical and radiological severity were all recorded.RESULTS:Hypertriglyceridemia was responsible for 7 of 133 cases of pancreatitis (5%);the remaining cases were of biliary (53%),idiopathic (26%),alcoholic (11%) or other (5%) origin.Compared with these remaining cases,the patients with hypertriglyceridemia were significantly younger,had more relapses,and more often had diabetes mellitus.They usually consumed alcohol or consumed it excessively on the days before admission.Also,the ε4 allele of the APOE gene was more common in this group (P<0.05).CONCLUSION:One of 20 episodes of acute pancreatitis is caused by hypertriglyceridemia and it is linked to genetic (ε4 allele) and comorbid factors such as diabetes and,especially,alcohol consumption. | Radka Ivanova Susana Puerta Alfonso Garrido Ignacio Cueto Ana Ferro María José Ariza Andrés Cobos Pedro González-Santos Pedro Valdivielso | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，1： | 26 |
| 2 | Analysis of mortality and risk factors associated with native valve endocarditis in drug users: The importance of vegetation size显示文摘 | Pilar Martín-Dávila Enrique Navas Jesús Fortún Jose Luis Moya Javier Cobo Vicente Pintado Carmen Quereda Manuel Jiménez-Mena Santiago Moreno | 2005 | American Heart Journal2005，，5： | 1 |
| 3 | Comparison of concomitant outcome achieved with fresh and cryopreserved donor oocytes vitri- fied by the cryotop method显示文摘 | Cobo A Kuwayama M Perez S | 2008 | Fertil Steril2008，89，6： | 1 |
| 4 | Risk of Episiotomy and Perineal Lacerations Recurring After First Delivery显示文摘 | Sebastian Manzanares Davinia Cobo Maria Dolores Moreno‐Martínez Mar Sánchez‐Gila Alicia Pineda | 2013 | Birth2013，，4： | 1 |
| 5 | Using RAPDs to study phylogenetic relationship in Rosa显示文摘 | Millan T Osuna F Cobos S | 1996 | Theoretical and Applied Genetics1996，92，： | 1 |
| 6 | Comparison of concomitant outcome achieved with fresh and cryopreserved donor oocytes vitrified by the cryotop method显示文摘 | Cobo A Kuwayama M Pérez S | | 0，，06： | 1 |
| 7 | Using RAPDS to study phylogenetic relationships in Rosa显示文摘 | MILLAN T OSUNA F COBOS S | 1996 | TAG1996，92，2： | 1 |
| 8 | Use of Subjective Global Assessment, Patient - Genera- ted Subjective Global Assessment and Nutritional Risk Screening 2002 to evaluate the nutritional status of non - critically ill patientson parenteral nutrition 显示文摘 | BADIA TAHULL M B COBO SACRISTAN S LEIVA BADOSA E | 2014 | Nutr Hosp2014，29，2： | 1 |
| 9 | Ant-based routing for wireless multimedia senso networks using multiple QoS metrics显示文摘 | COBO L QUINTERO A PIERRE S | 2010 | Computer Networks2010，54，17： | 1 |
| 10 | Vitrification : an ef- fective new approach to oocyte banking and preserving fer- tility in cancer patients 显示文摘 | Cobo A Domingo J Perez S | 2008 | Clinical & Translational Oncol- ogy2008，10，5： | 1 |
| 11 | Factors affecting the development of oxide scales on austenitic stainless steels during hot rolling in Steckel Mills 显示文摘 | Cobo S J Rainforth W M | 2008 | Metallurgical and Materials Transactions A2008，39，： | 1 |
| 12 | Storage of human oocytes in the vapor phase of nitrogen 显示文摘 | Cobo A Romero JL Perez S | 2010 | F ertil Steril2010，94，5： | 1 |
| 13 | Conservative treatment with tran-surethral resection,neoadjuvant chemotherapy followed by radio-chemotherapy in stage T2-3 transitional bladder cancer显示文摘 | Cobo M Delgado R Gil S | 2006 | Clin Transl Oncol2006，8，12： | 1 |
| 14 | Ant-based rou- ting for wireless multimedia sensor networks using multi- ple QoS metrics 显示文摘 | COBO L QUINTERO A PIERRE S | 2010 | Computer Netwroks2010，54，17： | 1 |
| 15 | Preliminary static analysis of suspension bridges显示文摘 | COBO DEL ARCO D APARICIO A S | 2001 | Engineering Structures2001，23，9： | 1 |
| 16 | Use of fluorescence in situ hybridization to assess the chromosomal status of embryos obtained from cryopreserved oocytes 显示文摘 | Cobo A Rubio C Gerli S | 2001 | Fertil Steril2001，75，2： | 1 |
| 17 | Secular trends of candidemia in a large tertiary-care hospital from 1988 to 2000: emergence of Candida parapsilosis 显示文摘 | San Miguel L G Cobo J Otheo E SAnchez Sousa A Abraira V Moreno S | 2005 | Infect Control Hosp Epidemio12005，26，： | 1 |
| 18 | Predictors of outcome after decompressive lumbar surgery and instru- mented posterolateral fusion 显示文摘 | Cobo S J Sendino RM Fabregate FM | 2010 | Eur Spine J2010，，11： | 1 |
| 19 | Effects of Probiotic Lactobacillus Casei DN-114 001 in Prevention of Radiation-Induced Diarrhea: Results From Multicenter, Randomized, Placebo-Controlled Nutritional Trial显示文摘 | Jordi Giralt José Perez Regadera Ramona Verges Jesus Romero Isabel de la Fuente Albert Biete Jesús Villoria Jose Maria Cobo Francisco Guarner | 2008 | International Journal of Radiation Oncology, Biology, Physics2008，，4： | 1 |
| 20 | Microstructural Evolution of Austen- ite Under Conditions Simulating Thin Slab Casting and Hot Direct Rolling显示文摘 | Cobo S J Sellars C M | | 0，，03： | 1 |
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