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42篇 您的检索式：作者名="CHRISTIANO P"

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	题名	作者	年代	出处	被引量
1	Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis显示文摘AIM:To investigate whether butyrate or glutamine enemas could diminish inflammation in experimental diversion colitis.METHODS:Wistar specific pathogen-free rats were submitted to a Hartmann's end colostomy and treated with enemas containing glutamine,butyrate,or saline.Enemas were administered twice a week in the excluded segment of the colon from 4 to 12 wk after the surgical procedure.Follow-up colonoscopy was performed every 4 wk for 12 wk.The effect of treatment was evaluated using video-endoscopic and histologic scores and measuring interleukin-1β,tumor necrosis factor-alpha,and transforming growth factor beta production in organ cultures by enzyme linked immunosorbent assay.RESULTS:Colonoscopies of the diverted segment showed mucosa with hyperemia,increased number of vessels,bleeding and mucus discharge.Treatment with either glutamine or butyrate induced significant reductions in both colonoscopic(P < 0.02) and histological scores(P < 0.01) and restored the densities of collagen fibers in tissue(P = 0.015;P = 0.001),the number of goblet cells(P = 0.021;P = 0.029),and the rate of apoptosis within the epithelium(P = 0.043;P = 0.011) to normal values.The high levels of cytokines in colon explants from rats with diversion colitis significantly decreased to normal values after treatment with butyrate or glutamine.CONCLUSION:The improvement of experimental diversion colitis following glutamine or butyrate enemas highlights the importance of specific luminal nutrients in the homeostasis of the colonic mucosa and supports their utilization for the treatment of human diversion colitis.	Rodrigo Goulart Pacheco Christiano Costa Esposito Lucas CM Müller Morgana TL Castelo-Branco Leonardo Pereira Quintella Vera Lucia A Chagas Heitor Siffert P de Souza Alberto Schanaider	2012	World Journal of Gastroenterology2012，18，32：	9
2	Seismic response of tiedback retaining walls显示文摘	Siller T J Christiano P P Bielak J	1991	Earthquake Engineering and Structural Dynamics1991，20，7：	1
3	Steady state harmonic response of a rigid plate baring on a liquid-saturated poroelastic halfspace 显示文摘	Halpern M R Christiano P	1986	Earthq Eng Struet Dyn1986，14，3：	1
4	Three- dimensional nonlinear study of piles显示文摘	TROCHANIS A M BIELAK J CHRISTIANO P	1991	Journal of Geoteehnieal Engineering ASCE1991，117，3：	1
5	Response of poroelastic half space to steady-state harmonic surface tractions显示文摘	HALPERN M R CHRISTIANO P	1986	Int J Numer Anal Met1986，10，6：	1
6	Steady-state harmonic response of a rigid plate bearing on a liquid-saturated poroelastic half space显示文摘	HALPERN M R CHRISTIANO P	1986	Earthq Eng Struct D1986，14，3：	1
7	Efficacy of cinacalcet with low-dose vitamin D in incident haemodialysis subjects with secondary hyperparathyroidism显示文摘	Urena-Torres P Bridges I Christiano C	2013	Nephrol Dial Transplant2013，28，5：	1
8	Steady-state harmonic response of a rigid plate bearing on a liquid-saturated poroelastic halfspace 显示文摘	HALPERN M R CHRISTIANO P	1986	Earthquake Engng Struct Dynam1986，14，：	1
9	Simplified Model for Analysis of One or Two Piles显示文摘	Bielak J Christiano P	1991	Journal of Geotechnical Engineering1991，117，3：	1
10	Three-dimensional nonlinear study of piles显示文摘	Trochanis A M Bielak J Christiano P	1991	Journal of Geotechnical Engineering ASCE1991，117，3：	1
11	Steady-state response of a rigid plate bearing on a liquid-saturated poroelastic halfspace显示文摘	Christiano P	1986	Earth Eng Struct Dyn1986，14，：	1
12	Simplified model for analysis of one or two piles显示文摘	Bielak J Christiano P	1991	Journal of Geotechnical Engineering ASCE1991，117，3：	1
13	Simplified model for analysis of one or two piles显示文摘	TROCHANIS A M BIELAK J CHRISTIANO P	1991	Geotechnical Engineering ASCE1991，117，3：	1
14	Three-dimensional nonlinear study of piles显示文摘	TROCHANIS A M BIELAK J CHRISTIANO P	1991	Journal of Geotechnical Engineering1991，117，3：	1
15	Three- dimensional non-linear study of piles 显示文摘	Trochanis A M Bielak J Christiano P	1991	Journal of Geotechnical and Geoenvironmental Engineering1991，117，3：	1
16	Three-dimensional nonlinear study of piles显示文摘	Trochanis A.M Bielak J Christiano P		0，，03：	1
17	Simplified model for analysis of one or two piles 显示文摘	Trochanis A M Bielak J Christiano P	1991	Journal of Geotechnical and Geoenvironmental Engineering1991，117，3：	1
18	Steady-state response of a rigid plate bearing on a liquid-saturated porodastic halfspace显示文摘	Halpern M R Christiano P	1986	Earthquake Eng Struct Dyn1986，14，3：	1
19	Silicone antifoam perfornmance: correlation with spreading and surfactant monolayer packing 显示文摘	JHA B K CHRISTIANO S P	2000	Langmuir2000，16，26：	1
20	Silicone antiibams performance: Correlation with spreading and surfactant monolayer packing 显示文摘	JHA B K CHRISTIANO S P SHAH D O	2000	Langmuir2000，16，：	1

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