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| 1 | Hollow mesoporous titania microsphere with low shell thickness/diameter ratio and high photocatalysis显示文摘 | Jianing Liu Gaowen Zhang Wei Ao Kan Yang Shaoxian Peng Christel Müller-Goymann | 2012 | Applied Surface Science2012，，20： | 2 |
| 2 | Prediction of the severity of colorectal lesion by fecal hemoglobin concentration observed during previous test in the French screening program显示文摘BACKGROUND The rate of positive tests using fecal immunochemical test(FIT)does not decrease with subsequent campaigns,but the positive predictive value of advanced neoplasia significantly decreases in subsequent campaign after a first negative test.A relationship between the fecal hemoglobin concentration(Fhb)and the opportunity to detect a colorectal cancer in subsequent campaign has been shown.AIM To predict the severity of colorectal lesions based on Fhb measured during previous colorectal cancer screening campaign.METHODS This etiological study included 293750 patients aged 50-74,living in Auvergne-Rhone-Alpes(France).These patients completed at least two FIT[test_((-1))and test_((0))]between June 2015 and December 2019.Delay between test_((-1))and test_((0))was>1year and test_((-1))result was negative(<150 ngHb/mL).The severity of colorectal lesions diagnosed at test_((0))was described according to Fhb measured at test_((-1))[Fhb_((-1))].The relationship between the severity classified in seven ordinal categories and the predictive factors was analyzed in an ordered multivariate polytomous regression model.RESULTS The test_((0))positive rate was 4.0%,and the colonoscopy completion rate was 97.1%in 11594 patients who showed a positive test_((0)).The colonoscopy detection rate was 77.7%in those 11254 patients who underwent a colonoscopy.A total of 8748 colorectal lesions were detected(including 2182 low-risk-polyps,2400 high-riskpolyp,and 502 colorectal cancer).The colonoscopy detection rate varied significantly with Fhb_((-1))[0 ngHb/mL:75.6%,(0-50 ngHb/mL):77.3%,(50-100 ngHb/mL):88.7%,(100-150 ngHb/mL):90.3%;P=0.001].People with a Fhb_((-1))within(100-150 ngHb/mL)(P=0.001)were 2.6(2.2;3.0)times more likely to have a high severity level compared to those having a Fhb_((-1))value of zero.This risk was reduced by 20%in patients aged 55-59 compared to those aged<55[adjusted odds ratio:0.8(0.6;1.0)].CONCLUSION The study showed that higher Fhb_((-1))is correlated to an increased risk of severity of colorectal lesions.This risk of severity increased among first-time participants(age<55)and the elderly(≥70).To avoid the loss of chance in these age groups,the FIT positivity threshold should be reduced to 100 ngHb/mL.The other alternative would be to reduce the time between the two tests in these age groups from the current 2 years to 1 year. | Christian Balamou Akoi Koivogui Christelle M Rodrigue Aurelie Clerc Claire Piccotti Anne Deloraine Catherine Exbrayat | 2021 | World Journal of Gastroenterology2021，27，31： | 2 |
| 3 | Prevalence of and risk factors for malaria,filariasis,and intestinal parasites as single infections or co-infections in different settlements of Gabon,Central Africa显示文摘Background:Malaria,filariasis,and intestinal parasitic infections(IPIs)are common and frequently overlap in developing countries.The prevalence and predictors of these infections were investigated in three different settlements(rural,semi-urban,and urban)of Gabon.Methods:During cross-sectional surveys performed from September 2013 to June 2014,451 individuals were interviewed.In addition,blood and stool samples were analysed for the presence of Plasmodium,filarial roundworm,intestinal protozoan,and helminth infections.Results:Intestinal parasitic infections(61.1%),including intestinal protozoa(56.7%)and soil-transmitted helminths(STHs)(22.2%),predominated,whereas Plasmodium falciparum(18.8%),Loa loa(4.7%),and Mansonella perstans(1.1%)were less prevalent.Filariasis and STHs were mainly found in rural settlements,whereas a higher plasmodial infection prevalence rate was observed in the periurban area.The most common IPI was blastocystosis(48.6%),followed by ascaridiasis(13.7%),trichuriasis(11.8%),amoebiasis(9.3%),giardiasis(4.8%),and strongyloidiasis(3.7%).Hookworm was detected in one adult from rural Dienga.Adults had a higher prevalence of Blastocystis hominis and STHs,whereas Giardia duodenalis was more frequently observed among children aged below 5 years(P<0.01).The polyparasitism rate was 41.5%,with 7.0%Plasmodium-IPIs and 1.8%Plasmodium-STH co-infections.The multivariate analysis showed that living in a suburban area,belonging to the age group of 5-15 years,having none or a secondary education,or having an open body water close to home were significant risk factors for malaria(P≤0.01).For STH infections,identified risk factors were drinking untreated water and living in a rural area(P≤0.04).No significant predictors were identified for IPIs and malaria-IPI co-infection.Conclusions:This study reports a high prevalence of IPIs and intestinal protozoa,but a low rate of malaria-IPI co-infections in the study sites.Improvements in the living conditions of the population such as adequate water supply and proper health education and sanitation should be integrated into control strategies for malaria,STHs,and IPIs. | Noe Patrick M’bondoukwe Eric Kendjo Denise Patricia Mawili-Mboumba Jeanne Vanessa Koumba Lengongo Christelle Offouga Mbouoronde Dieudonne Nkoghe Fousseyni Toure Marielle Karine Bouyou-AkotetAuthor details | 2018 | Infectious Diseases of Poverty2018，7，1： | 2 |
| 4 | Use of human pluripotent stem cells to study and treat retinopathies显示文摘Human cell types affected by retinal diseases(such as age-related macular degeneration or retinitis pimentosa) are limited in cell number and of reduced accessibility. As a consequence, their isolation for in vitro studies of disease mechanisms or for drug screening efforts is fastidious. Human pluripotent stem cells(h PSCs), either of embryonic origin or through reprogramming of adult somatic cells,represent a new promising way to generate models of human retinopathies, explore the physiopathological mechanisms and develop novel therapeutic strategies. Disease-specific human embryonic stem cells were the first source of material to be used to study certain disease states. The recent demonstration that human somatic cells, such as fibroblasts or blood cells, can be genetically converted to induce pluripotent stem cells together with the continuous improvement of methods to differentiate these cells into disease-affected cellular subtypes opens new perspectives to model and understand a large number of human pathologies, including retinopathies. This review focuses on the added value of h PSCs for the disease modeling of human retinopathies and the study of their molecular pathological mechanisms. We also discuss the recent use of these cells for establishing the validation studies for therapeutic intervention and for the screening of large compound libraries to identify candidate drugs. | Karim Ben M'Barek Florian Regent Christelle Monville | 2015 | World Journal of Stem Cells2015，7，3： | 2 |
| 5 | Helicobacer pylori initiate or perpetuate immune thrombocytopenic purpura? 显示文摘 | Marc M Nichola C Christelle J | 2004 | Blood2004，103，3： | 1 |
| 6 | Personality and Team Performance : A Meta - Analysis 显示文摘 | Miranda A G Peeters Harrie F J M Vantuijl Christel G Rutte Isabelle M M J Reymen | 2006 | European Journal of Personality2006，，20： | 1 |
| 7 | Leukemia inhhibitory factor:Role in human mesenchymal stem cells mediated immunosuptor:Role in human mesenchymal stem cells mediated immunosuppression显示文摘 | Aisha N Christelle M Sandrine B | 2008 | Cell Immuol2008，253，1： | 1 |
| 8 | Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial显示文摘 | Marcia S Brose Christopher M Nutting Barbara Jarzab Rossella Elisei Salvatore Siena Lars Bastholt Christelle de la Fouchardiere Furio Pacini Ralf Paschke Young Kee Shong Steven I Sherman Johannes W A Smit John Chung Christian Kappeler Carol Pe?a István Mo | 2014 | The Lancet2014，，： | 1 |
| 9 | Pharmacoki- netics of cyanide in poisoning of dogs, and the effect of 4-dimethylaminophenol or thiosulfate显示文摘 | Christel D Eyer P Hegemann M | 1977 | Archives of Toxicology1977，38，3： | 1 |
| 10 | Effe-ct of beeswax modification on the lipid matrix and solid lipid nanoparticle crystallinity显示文摘 | ATTAMA A A CHRISTEL C MüLLER-GOYMANN | 2008 | Colloids Surfaces A2008，315，13： | 1 |
| 11 | Determination of ethylphenol compounds in wine by headspace solid-phase microextraction in conjunction with gas chromatography and flame ionization detection 显示文摘 | Marie-Carmen M Christelle P Valerie G | 2002 | Analytica Chimica Acta2002，458，： | 1 |
| 12 | 显示文摘 | Arnold M Stux Christel Laberty Robert Karen E Swider Ly- ons | 2008 | Journal of Solid State Chemistry2008，181，： | 1 |
| 13 | New intumescent formulations of fire-retardant polypropylene-discussion of the free radical mechanism of the formation of carbonaceous protective materiaJ during the therme-oxidative treatment of the additives显示文摘 | Le Bras M Bourbigot S Christelle D | 1996 | Fire Mater1996，20，4： | 1 |
| 14 | Peyerimhoff study of the dependence of spin-orbit matrix elements on AO basis set composition for inner and valence shells: Besults for the multiplet splitting of X3 - and C311 of SO and X' II in SO' 显示文摘 | RAINER K CHRISTEL M M SIGRID D | 1983 | Chem Phys1983，76，3： | 1 |
| 15 | Diclofenac sodium delivery to the eye:in vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct显示文摘 | ATTAMA A A REICHL S CHRISTEL C M | 2008 | Int J Pharm2008，355，12： | 1 |
| 16 | Biomechanical compatibility and design of ceramic implants for orthopedic surgery显示文摘 | CHRISTEL P MEUNIER A DORLOT J M | 1988 | Bioceramics1988，23，： | 1 |
| 17 | Biomechanical compatibility and design of ceramic implants for orthopedic surgery Bioceramics: Material characteristics versus in vivo behavior 显示文摘 | Christel P Meunier A Dorlot J M | 1988 | Ann NY Acad Sci1988，523，： | 1 |
| 18 | Proteinase inhibitors from Nicotiana alata enhance plant resistance to insect pests显示文摘 | Heath RL Mcdonald G Christeller JT Lee M Bateman K West J Vanheeswuck R Anderson MA | | 0，，9： | 1 |
| 19 | Lessons Leamed from Building a Terabyte Digital Video Library 显示文摘 | Wactlar H D Christel M G Gong Y Hauptmann A G | 1999 | IEEE Computer1999，42，2： | 1 |
| 20 | Inhibition of by Maillard reaction Products Prepared from Glucose or fructose with L-Cysleine under Various Conditions of pH and Temperature 显示文摘 | Catherine B Christelle Polyphenoloxidase from Apple M Jacques N | 2004 | LWT2004，37，： | 1 |
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