|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Development of a script of phonemically balanced monosyllable lists of Mandarin-Chinese显示文摘Objectives To develop a set of monosyllable audiometry test material that can be used in speech recognition testing in Mandarin Chinese. Materials and Methods In an effort to improve reliability and efficiency in clinical practice, a set of 30 test lists of 25 monosyllable test items each was designed with consideration of the following: length of the list, phonemical balance (PB), word utility frequency, coverage of common words, and equivalency among lists. The 30 lists contained 750 monosyllabic words and were constructed on the basis of Chinese phoneme distribution probability summarized in the Manual of Acoustic. The occurrence incidence of the 22 consonants, 36 vowels, and 4 tones of the Chinese Mandarin characters in the 30 test lists were calculated. To achieve PB, 489 monosyllables were selected from the 2500 most commonly used Chinese characters and the 4000 most commonly used Chinese phrases to compile the 30 monosyllable test lists using a computer algorithm with manual adjustment. Results Thirty phonemical balanced word lists of common Mandarin Chinese monosyllabic words were compiled. Each list consisted of 25 monosyllables. A total of 489 phonemes (consonants, vowels and tones) were included in the set. Conclusions This set of lists can potentially be used as the basic lists for future development of Mandarin PB monosyllable speech test materials. | JI Fei, CHEN Aiting, ZHAO Yang, XI Xin, HAN Dongyi Departments of Otorhinolaryngology-Head and Neck Surgery, Institute of Otorhinolaryngology, General Hospital of People’s Liberation Army, Beijing 100853, China | 2010 | Journal of Otology2010，5，1： | 4 |
| 2 | Discrete-time Indefinite LQ Control with State and Control Dependent Noises显示文摘 | M. Ait Rami X. Chen X.Y. Zhou | 2002 | Journal of Global Optimization (-)2002，，3： | 1 |
| 3 | Solvability and Asymptotic Behavior of Generalized Riccati Equations Arising in Indefinite Stochastic LQ Controls显示文摘 | Ait Rami M Chen X Moore J B | 2001 | IEEE Transactions on Automatic Control2001，46，： | 1 |
| 4 | Discrete -time Indefinite LQ Control with State and Control Dependent Noises显示文摘 | Ait Rami M Chen X Zhou X Y | 2002 | Journal of Global Optimization2002，23，： | 1 |
| 5 | Overexpression of Hepcidin Alleviates Steatohepatitis and Fibrosis in a Diet-induced Nonalcoholic Steatohepatitis显示文摘Background and Aims:Iron overload can contribute to the progression of nonalcoholic fatty liver disease(NAFLD)to nonalcoholic steatohepatitis(NASH).Hepcidin(Hamp),which is primarily synthesized in hepatocytes,is a key reg-ulator of iron metabolism.However,the role of Hamp in NASH remains unclear.Therefore,we aimed to elucidate the role of Hamp in the pathophysiology of NASH.Methods:Male mice were fed a choline-deficient L-amino acid-defined(CDAA)diet for 16 weeks to establish the mouse NASH model.A choline-supplemented amino acid-defined(CSAA)diet was used as the control diet.Recombinant adeno-asso-ciated virus genome 2 serotype 8 vector expressing Hamp(rAAV2/8-Hamp)or its negative control(rAAV2/8-NC)was administered intravenously at week 8 of either the CDAA or CSAA diet.Results:rAAV2/8-Hamp treatment markedly decreased liver weight and improved hepatic steatosis in the CDAA-fed mice,accompanied by changes in lipogenesis-related genes and adiponectin expression.Compared with the control group,rAAV2/8-Hamp therapy attenuated liver damage,with mice exhibiting reduced histological NAFLD inflammation and fibrosis,as well as lower levels of liver enzymes.Moreover,α-smooth muscle actin-positive acti-vated hepatic stellate cells(HSCs)and CD68-postive mac-rophages increased in number in the CDAA-fed mice,which was reversed by rAAV2/8-Hamp treatment.Consistent with the in vivo findings,overexpression of Hamp increased adi-ponectin expression in hepatocytes and Hamp treatment inhibited HSC activation.Conclusions:Overexpression of Hamp using rAAV2/8-Hamp robustly attenuated liver stea-tohepatitis,inflammation,and fibrosis in an animal model of NASH,suggesting a potential therapeutic role for Hamp. | Hui Chen Wenshan Zhao Xuzhen Yan Tao Huang Aiting Yang | 2022 | Journal of Clinical and Translational Hepatology2022，10，4： | 0 |
| 6 | AUDITORY BRAINSTEM RESPONSES IN SENILE PRESBYCUSIS PATIENTS OVER 90 YEARS显示文摘Objective To analyze the characteristics of auditory brainstem response(ABR) in presbycusis patients elder than 90 years. Methods Fourteen presbycusis patients elder than 90 years(presbycusis group, 91.1.4±1.3 years, 26 ears) and 9 normal-hearing young adults(control group, 22.7±1.2 years, 18 ears) participated in the study. Alternative click-evoked ABRs were recorded in both groups. The peak latency(PL) of peak I,Ⅲ, and V, and the inter-peak latency(IPI) of I-Ⅲ, Ⅲ-V, and I-V were compared between groups. Results In elder presbycusis patients, the occurrence rate of peak I and Ⅲ were both 76.9%, and that of peak V was84.6%. In presbycusis group, the peak latencies of I, Ⅲ, V were significantly longer than that of control group(P<0.001). There was no significant difference between groups in the IPI of peak I-I Ⅲ(P=0.298,peak Ⅲ-V(P=0.254) and peak I-V(P=0.364). Conclusions Auditory brainstem responses in presbycusis patients elder than 90 years showed worse wave | CHEN Aiting LIANG Sichao ZHANG Ruining GUO Weiwei ZHOU Qiyou JI Fei | 2014 | Journal of Otology2014，9，1： | 0 |
| 7 | The New Clinical Skills Training Module for the Master's Degree in Ophthalmology显示文摘This article aims at the principle problems noticed in the process of training postgraduates in ophthalmology for clinical skills (POCs). Alteration of the training objectives and training curricula,.as well as the clinical department training plans,.will allow POCs to obtain a systematic and standardized education to establish their general attitude toward medical life and career plans. This will help to improve their clinical skills and establish professional ethics that will protect the interests of patients and promote the healthy and harmonious development of the Eye Hospital. Furthermore, the Ophthalmology Center could cultivate a number of outstanding postgraduate students that match its tier, to describe the quality of the training for the master's degree in Ophthalmology. | Meihua Le Weiguo Chen Aiting Yu | 2013 | Eye Science2013，28，4： | 0 |
| 8 | UTILITY OF VIBRANT SOUNDBRIDGE IN PATIENTS WITH CONGENITAL MIDDLE AND OUTER EAR DEFORMITIES | ZOU Yihui LI Jianan CHEN Aiting DAI Bu HAN Dongyi LIU Huizhan YANG Shiming | 2012 | Journal of Otology2012，7，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员