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| 1 | Distinct regulatory mechanism of immunoglobulin gene transcription in epithelial cancer cells显示文摘The restriction of immunoglobulin(Ig)expression to B lymphocytes is well established.However,several reports have confirmed that the Ig gene can be expressed in many non-B cancer cells and/or some normal cells.Our aim is to determine whether the Ig gene promoter can be activated in non-B cancer cells and to identify the regulatory mechanism for Ig gene expression.Our results show that the Ig promoter of VH4-59 was activated in several non-B cancer cell lines.Moreover,two novel positive regulatory elements,an enhancer-like element at 2800 to 2610 bp and a copromoter-like element at 2610 to 2300 bp,were identified in two epithelial cancer cell lines,HeLa S3 and HT-29.The octamer element(59-ATGCAAAT-39)located in the Ig promoter,a crucial element for B-cell-derived Ig gene transcription,was also very important for non-B-cell-derived Ig gene transcription.More importantly,we confirmed that octamer-related protein-1(Oct-1),but not Oct-2,was a crucial transcriptional factor for Ig gene transcription due to its ability to bind to the octamer element of the Ig promoter in epithelial cancer cells.These results suggested the presence of a distinct regulatory mechanism for Ig gene expression in non-B cancer cells. | Xiaohui Zhu Lina Wu Li Zhang Peng Hao Shuai Zhang Jing Huang Jie Zheng Yinan Liu Wenjun Li Yingmei Zhang Chunyan Zhou Youhui Zhang C Cameron Yin Xiaoyan Qiu | 2010 | Cellular & Molecular Immunology2010，7，4： | 5 |
| 2 | Image-adaptive watermarking using visual models显示文摘 | C I Podilchuk Wenjun Zeng | 1998 | IEEE Journals on Selected Area in Communications: Special issue on Copyright and Privacy Protection1998，16，4： | 1 |
| 3 | Quality design and environmental implications of green consumerism in remanufacturing显示文摘 | Wenjun Gu Dilip Chhajed Nicholas C Petruzzi | 2015 | Int J of Production Economics2015，162，4： | 1 |
| 4 | Image-adaptive watermarking using fisual models显示文摘 | PODILCHUK C I ZENG Wenjun | 1998 | IEEE Journal on Selected Areas in Communications1998，16，4： | 1 |
| 5 | Experimental demonstration of near-infrared negative-index metamaterials显示文摘 | Zhang Shuang Fan Wenjun Panoiu N C | 2005 | Physical Review Letters2005，95，13： | 1 |
| 6 | Image-adaptive watermarking using visual models 显示文摘 | PODILCHUK C I Zeng Wenjun | 1998 | IEEE Journal on Selected Areas in Communications1998，16，4： | 1 |
| 7 | Turbulent exchange processes with in and above astrew mulch, Part I: Mean wind speed and turbulent statistics显示文摘 | Novak M D C Wenjun | 2000 | Agric For Meterol2000，102，： | 1 |
| 8 | Microencapsulation of uncharged low molecular weight organic materials by polyeletrolyte multilayer self-assembly 显示文摘 | FRANK C WENJUN Y DIETER T | 2000 | Langmuir2000，16，23： | 1 |
| 9 | Image-adaptive Watermarking Using Visual Models显示文摘 | C I Podilchuk Wenjun Zeng | 1998 | IEEE Journals on Selected Area in Communications:Special Issue on Copyright and Privacy Protection1998，16，4： | 1 |
| 10 | Image-adaptive watermarking using visual models 显示文摘 | Podilchuk C I Zeng Wenjun | 1998 | IEEE Journal on Selected Areas in Communications1998，16，4： | 1 |
| 11 | Image-adaptive watermarking using visual models显示文摘 | Podilchuk C J Zeng Wenjun | 1998 | IEEE Journal on Selected Area in Communications1998，16，4： | 1 |
| 12 | Optical negative-index bulk metamaterials consisting of 2D per- forated metal-dielectric stacks 显示文摘 | Zhang Shuang Fan Wenjun Panoiu N C | 2006 | Opt Express2006，14，15： | 1 |
| 13 | Image-adaptive Watermarking using visual models显示文摘 | Podilchuk C I Wenjun Zeng | 1998 | IEEE Journal of Selected Areas in Communication1998，16，4： | 1 |
| 14 | Image-adaptive watermarking using visual models显示文摘 | Podilchuk C I Zeng Wenjun | 1998 | IEEE Journal on Selected Areas in Communications1998，16，4： | 1 |
| 15 | Digital Image Watermarking Using Visual Models显示文摘 | Podilchuk C I Zeng Wenjun | 1998 | IEEE Journal on Selected Area in Com- munication1998，16，4： | 1 |
| 16 | New calculation methods of diurnal distribution of solar radiation and its in- terception by canopy over complex terrain 显示文摘 | Wang Shusen Chen Wenjun Josef C | 2002 | Ecological Modelling2002，00，： | 1 |
| 17 | Image-adaptive Watermarking Using Visual Models显示文摘 | Podilchuk C I Zeng Wenjun | 1998 | IEEE Journal on Selected Areas in Communications1998，16，4： | 1 |
| 18 | Image - adaptive watermarking using visual models 显示文摘 | PODILCHUK C I ZENG WENJUN | 1998 | IEEE Journal on Selected Areas in Communications1998，16，4： | 1 |
| 19 | Digital Image Watermarking Using Visual Models 显示文摘 | Podichuk C I Zeng Wenjun | 1998 | IEEE Journal on Selected Area in Communication1998，16，4： | 1 |
| 20 | Image adaptive water marking using visual models 显示文摘 | Podilchuk C I Zeng Wenjun | 1998 | IEEE Journal of Selected Areas in Communication1998，16，4： | 1 |
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