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| 1 | National trends in resection of the distal pancreas显示文摘AIM:To investigate national trends in distal pancreatectomy(DP) through query of three national patient care databases.METHODS:From the Nationwide Inpatient Sample(NIS,2003-2009),the National Surgical Quality Improvement Project(NSQIP,2005-2010),and the Surveillance Epidemiology and End Results(SEER,2003-2009) databases using appropriate diagnostic and procedural codes we identified all patients with a diagnosis of a benign or malignant lesion of the body and/or tail of the pancreas that had undergone a partial or distal pancreatectomy.Utilization of laparoscopy was defined in NIS by the International Classification of Diseases,Ninth Revision correspondent procedure code;and in NSQIP by the exploratory laparoscopy or unlisted procedure current procedural terminology codes.In SEER,patients were identified by the International Classification of Diseases for Oncology,Third Edition diagnosis codes and the SEER Program Code Manual,third edition procedure codes.We analyzed the databases with respect to trends of inpatient outcome metrics,oncologic outcomes,and hospital volumes in patients with lesions of the neck and body of the pancreas that underwent operative resection.RESULTS:NIS,NSQIP and SEER identified 4242,2681 and 11 082 DP resections,respectively.Overall,laparoscopy was utilized in 15%(NIS) and 27%(NSQIP).No significant increase was seen over the course of the study.Resection was performed for malignancy in 59%(NIS) and 66%(NSQIP).Neither patient Body mass index nor comorbidities were associated with operative approach(P = 0.95 and P = 0.96,respectively).Mortality(3% vs 2%,P = 0.05) and reoperation(4% vs 4%,P = 1.0) was not different between laparoscopy and open groups.Overall complications(10% vs 15%,P < 0.001),hospital costs [44 741 dollars,interquartile range(IQR) 28 347-74 114 dollars vs 49 792 dollars,IQR 13 299-73 463,P = 0.02] and hospital length of stay(7 d,IQR 4-11 d vs 7 d,IQR 6-10,P < 0.001) were less when laparoscopy was utilized.One and two year survival after resection for malignancy were unchanged over the course of the study(ductal adenocarinoma 1-year 63.6% and 2-year 35.1%,P = 0.53;intraductal papillary mucinous neoplasm and nueroendocrine 1-year 90% and 2-year 84%,P = 0.25).The majority of resections were performed in teaching hospitals(77% NIS and 85% NSQIP),but minimally invasive surgery(MIS) was not more likely to be used in teaching hospitals(15% vs 14%,P = 0.26).Hospitals in the top decile for volume were more likely to be teaching hospitals than lower volume deciles(88% vs 43%,P < 0.001),but were no more likely to utilize MIS at resection.Complication rate in teaching and the top decile hospitals was not significantly decreased when compared to non-teaching(15% vs 14%,P = 0.72) and lower volume hospitals(14% vs 15%,P = 0.99).No difference was seen in the median number of lymph nodes and lymph node ratio in N1 disease when compared by year(P = 0.17 and P = 0.96,respectively).CONCLUSION:There appears to be an overall underutilization of laparoscopy for DP.Centralization does not appear to be occurring.Survival and lymph node harvest have not changed. | Armando Rosales-Velderrain Steven P Bowers Ross F Goldberg Tatyan M Clarke Mauricia A Buchanan John A Stauffer Horacio J Asbun | 2012 | World Journal of Gastroenterology2012，18，32： | 8 |
| 2 | Surface modifica- tion of poly(e-caprolactone) using a dielectric barrier discharge in atmospheric pressure glow discharge mode显示文摘 | Little U Buchanan F Harkin-Jones E | 2009 | Acta Biomate- rialia2009，5，6： | 1 |
| 3 | Ovine dinucleotide repent polymorphism at the MAF 33 Locus显示文摘 | Buchanan F C Crawford A M | 1992 | Animal Genetics1992，23，： | 1 |
| 4 | Ovine microsatellites at the Oar FCBll ,Oar FCB128 ,Oar FCB193,0arFCB266 and OarFCB304 Loci 显示文摘 | Buchanan F C Crraford A M | 1993 | Animal Genetics1993，24，： | 1 |
| 5 | Microsatellite evolution in congeneric mammals:domesticand bighorn sheep显示文摘 | FORBES S H HOGG J T BUCHANAN F C | 1995 | Mol Biol Evul1995，12，6： | 1 |
| 6 | Does Decarboxyla- tion Lead to Cross--Linking in Low-Rank Coals 显示文摘 | Thorns P E Phillip F B Buchanan A C | 1996 | Energy Fuels1996，10，6： | 1 |
| 7 | A study on the rate of degradation of the bioabsorbable polymer polyglycolic acid(PGA)显示文摘 | Shawe S Buchanan F Harkin J E | 2006 | J Mater Sci2006，41，： | 1 |
| 8 | Effect ofpatient sex on general anaesthesia and recovery 显示文摘 | BUCHANAN F F MYLES P S CICUTTINI F | 2011 | Br JAnaesth2011，106，6： | 1 |
| 9 | Assignment of ^1H-NMR and ^13C-NMR spectra and investigation of hindered side-chain rotation in lupeol derivatives显示文摘 | Burns D Reynolds W F Buchanan G | 2000 | Magn Reson Chem2000，38，： | 1 |
| 10 | Growth and Feed Utilization Efficiencies of Seawater Atlantic Salmon,Salmon Salar L fed a Diet Containing Supplementary Enzymes显示文摘 | Carter C G Houlihan D F Buchanan B | 1994 | Aquaculture and Fisheris Management1994，25，1： | 1 |
| 11 | Declining blood lead and zine protoporphyrin levels in Ecuadorian Andean children显示文摘 | Ortega F Counter SA Buchanan LH | 2013 | Clin Biochem2013，46，1314： | 1 |
| 12 | Starch Xanthide Reinforced Styrene-Butadiene Rubber:Compounding to Reduce Water Sensitivity显示文摘 | Buchanan R A Doane W M Russel C R Kwolek W F | 1975 | J Elastomers Plast1975，795，： | 1 |
| 13 | Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels显示文摘 | Buchanan F C Fitzsimmons C J VanKessel A G | 2002 | Genet Sel Evol2002，34，： | 1 |
| 14 | Three di- mensional microfluidic collagen hydrogels for investiga- ting flow - mediated tumor - endothelial signaling and vascular organization 显示文摘 | Buchanan C F Voigt E E Szot C S | 2014 | Tissue Eng2014，20，1： | 1 |
| 15 | Starch in rubber:Influence if starch type and concomitant variables in reinforcement of styrene-butadiene rubbers显示文摘 | Buchanan R A Kwolek W F Katz H C | 1971 | Die Starke1971，23，10： | 1 |
| 16 | Linkage mapping of the tyrosinase gene to bovine chromosome 29显示文摘 | Schmidtz B H Buchanan F C Plante Y | 2001 | Animal Ge- netics2001，32，2： | 1 |
| 17 | 果糖-2,6-二磷酸对番茄果实PFP酶活化效应的巯基依赖性显示文摘在无二硫苏糖醇(DTT)存在下得到部份纯化的氧化型PFP酶,在广泛的pH范围内(pH6.0~9.0)失去其大部分对果糖2,6-二磷酸的敏感性。活化效应可藉与DTT保温得到恢复而不改变其最适pH值。在与DTT保温过程中,酶对果糖2,6-二磷酸的亲和力逐步增加。氧化型酶的K_a值(对果糖2,6-二磷酸)在酶与DTT保温(pH8)1h之后从1400nmol/L下降到约50nmol/L。 在DTT存在下纯化的酶(还原型)经低浓度5,5′-二硫代双(2-硝基苯甲酸)(DTNB)处理,在使酶活性迅速失活的同时引起酶对果糖2,6-二磷酸脱敏。这一过程可为DTT处理所回复。从小麦胚中纯化的硫氧还蛋白h在恢复酶活性和酶的果糖2,6-二磷酸敏感性的效应中表明,细胞内的氧化还原状态可能藉以改变酶对果糖2,6-二磷酸的亲和力而调节PFP酶的活性。 | 吴敏贤 Wong JH Kiss F Buchanan BB | 1991 | 植物生理学报(0257-4829)1991，17，3： | 1 |
| 18 | Evaluating the strategic plans of public libraries : An inspection-based approach 显示文摘 | Buchanan S Cousins F | 2012 | Library & Information Science Research2012，34，2： | 1 |
| 19 | Mechanistic investigation into the formation of polycyclic aromatic hy- drocarbons from the pyrolysis of plant steroids 显示文摘 | Britt P F Buchanan A C Kidder M M | 2001 | Fuel2001，80，12： | 1 |
| 20 | Effect of probiotlc supplementation on performance, fecal parameters and digestibility in growing-finishing swine 显示文摘 | MASWELL C V BUCHANAN D S OWENS F N | 1983 | Animal Science Research Report1983，114，： | 1 |
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