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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Potential role of Limosilactobacillus fermentum as a probiotic with anti-diabetic properties: A review显示文摘Oxidative stress,inflammation,and gut microbiota impairments have been implicated in the development and maintenance of diabetes mellitus.Strategies capable of recovering the community of commensal gut microbiota and controlling diabetes mellitus have increased in recent years.Some lactobacilli strains have an antioxidant and anti-inflammatory system capable of protecting against oxidative stress,inflammation,and diabetes mellitus.Experimental studies and some clinical trials have demonstrated that Limosilactobacillus fermentum strains can beneficially modulate the host antioxidant and anti-inflammatory system,resulting in the amelioration of glucose homeostasis in diabetic conditions.This review presents and discusses the currently available studies on the identification of Limosilactobacillus fermentum strains with anti-diabetic properties,their sources,range of dosage,and the intervention time in experiments with animals and clinical trials.This review strives to serve as a relevant and well-cataloged reference of Limosilactobacillus fermentum strains capable of inducing anti-diabetic effects and promoting health benefits. | Diego Cabral Lacerda Paulo César Trindade da Costa Paula Brielle Pontes Lucas Alves Carneiro dos Santos JoséPatrocínio Ribeiro Cruz Neto Cristiane Cosmo Silva Luis Vanessa Polyana de Sousa Brito JoséLuiz de Brito Alves | 2022 | World Journal of Diabetes2022，13，9： | 3 |
| 3 | Posttreatment of a brewery wastewater using a sequencing batch reactor 显示文摘 | Rordrigues Ana C Brito Antonio G Melo Luis F | 2001 | Water Environment Research2001，73，1： | 2 |
| 4 | Gut-microbiome-brain axis:the crosstalk between the vagus nerve,alpha-synuclein and the brain in Parkinson's disease显示文摘This critical review of the literature shows that there is a close link between the microbiome,the gut,and the brain in Parkinson's disease.The vagus nerve,the main component of the parasympathetic nervous system,is involved in the regulation of immune response,digestion,heart rate,and control of mood.It can detect microbiota metabolites through its afferents,transferring this gut information to the central nervous system.Preclinical and clinical studies have shown the important role played by the gut microbiome and gut-related factors in disease development and progression,as well as treatment responses.These findings suggest that the gut microbiome may be a valuable target for new therapeutic strategies for Parkinson's disease.More studies are needed to better understand the underlying biology and how this axis can be modulated for the patient's benefit. | Júlio César Claudino dos Santos Leandro Freitas Oliveira Felipe Micelli Noleto Camilla Teixeira Pinheiro Gusmão Gerly Anne de Castro Brito Glauce Socorro de Barros Viana | 2023 | Neural Regeneration Research2023，18，12： | 2 |
| 5 | Bacteriocin production by Lactobacillus pentosus B96 can be expressed as a function of temperature and NaC1 concentration显示文摘 | DELGADO A BRITO D PERES C | 2005 | Food Microbiology2005，22，6： | 1 |
| 6 | Descriptive study on pulmonary embolism in an urban-teaching hospital 显示文摘 | SCHWED D MURALI G BRITO C | 2006 | Chest2006，130，： | 1 |
| 7 | Different expression levels of alpha3/4 fucosyhransferases and Lewis determinants in ovarian carcinoma tissues and cell lines 显示文摘 | Escrevente C Machado E Brito C | 2006 | Int J Oncol2006，29，3： | 1 |
| 8 | Ultrasonic Doppler Velocimetry in Liquid Gallium 显示文摘 | Brito D Natal H C Cardin P | 2001 | Experiments in Fluids2001，31，6： | 1 |
| 9 | Zero-dimensional model for preliminary design of ablative pulsed plasma Teflon thrusters 显示文摘 | Brito C M Elaskar S A Brito H H | 2004 | Journal of Propulsion and Power2004，20，6： | 1 |
| 10 | Optimisation and validation of a quantitative and confirmatory LC-MS method for multi-residue analyses ofβ-lactam and tetracycline antibiotics in bovine muscle显示文摘 | REZENDE C P ALMEIDA M P BRITO R B | 2012 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess2012，29，4： | 1 |
| 11 | Effect of the gamma radiation dose rate on psychrotrophic bacteria, thiobarbituric acid reactive substances, and sensory characteristics of mechanically deboned chicken meat 显示文摘 | Brito P P Azevedo H Cipolli K M Fukuma H T Moutao G B Roque C V Miya N T Pereira J L | 2011 | Journal of Food Science2011，76，2： | 1 |
| 12 | Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death显示文摘 | Brito C Naviliat M Tiscornia AC | 1999 | J Immunol1999，162，6： | 1 |
| 13 | Specification of exception flow in software architecture显示文摘 | Castor F F Brito P H Rubira C M | 2006 | The Journal of System & Software2006，79，10： | 1 |
| 14 | The effect of eyestalk ablation on the energy balance of the pink shrimp, Penaeus notialis 显示文摘 | Rosas C Fernandez I Brito R | 1993 | Comparative Biochemistry and Physiology Part A : Physiology1993，104，1： | 1 |
| 15 | Community genomics among stratified microbial assemblages in the ocean's interior显示文摘 | DeLong E F Preston C M Mincer T Rich V Hallam S J Frigaard N U Martinez A Sullivan M B Edwards R Brito B R Chisholm S W Karl D M | | 0，，5760： | 1 |
| 16 | Photovoltaic potential in a Lisbon suburb using LiDAR data显示文摘 | Brito M C Gomes N Santos T | 2012 | Solar Energy2012，86，1： | 1 |
| 17 | Sintering and Crystallite Growth of Nanocrystalline Copper Doped Tin Oxide显示文摘 | SANTILLI C V PULCINELLI S H BRITO G E S | 1999 | J Phys Chem B1999，103，14： | 1 |
| 18 | AQP4 expression in striatal primary cultures is regulated by dopamine-implica-tions for proliferation of astrocytes显示文摘 | Küppers E Gleiser C Brito V | | 0，，11： | 1 |
| 19 | Determination of trace element concentrations in tomato samples at different stages of maturation by ICP OES and ICP-MS following microwave-assisted digestion显示文摘 | BRESSY F C BRITO G B BARBOSA I S | 2013 | Microchemical Journal2013，109，： | 1 |
| 20 | Up-regulation of chemokine C-C ligand 2 (CCL2) and C-X-C chemokine 8 (CXCLS) expression by monocytes in chronic idiopathic urticaria显示文摘 | Santos J C de Brito C A Futata E A | 2012 | Clin Exp Immunol2012，167，1： | 1 |
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