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| 1 | RNA-Based Biocontrols--A New Paradigm in Crop Protection显示文摘Modern agribusiness plays a vital role in safeguarding and improving the production,quality,and quantity of food,feed,fiber,and fuel.Growing concerns over the impact of chemical pesticides on health and the environment have stimulated the industry to search for alternative and greener solutions.Over the last years,the RNA interference(RNAi)process has been identified as a very promising new approach to complement the arsenal of foliar spray,soil,or seed treatments applied as chemical and biological pest control agents,and of plant-incorporated protectants(PIPs).RNA-based active ingredients(AIs)possess a unique mode of action and can be implemented via both genetic modification(GM)and biocontrol approaches.RNA-based AIs promise to deliver the selectivity and sustainability desired in future crop protection agents.This is due to their utilization of a natural process to exert control and their high level of selectivity,which leads to reduced risk for non-target organisms(NTOs).This review discusses the advantages and limitations of RNA-based solutions in crop protection and recent research progress toward RNA-based biocontrols against the Colorado potato beetle(CPB),corn rootworm(CRW),and soy stink bug(SSB).Many challenges still exist on the road to the implementation of a broad range of RNA-based products and their widespread use and application.Despite these challenges,it can be expected that RNA-based AIs will become valuable new tools complementing the current arsenal of crop-protection solutions. | Matthew Bramlett Geert Plaetinck Peter Maienfisch | 2020 | Engineering2020，6，5： | 4 |
| 2 | Posttraumatic hypothermia is neuroprotective in a model of traumatic brain injury complicated by a secondary hypoxic insult 显示文摘 | Matsushita Y Bramlett HM Alonso O | 2001 | Crit Care Med2001，29，11： | 1 |
| 3 | Protection in animal models of brain and spinal cord injury with mild to moderate hypothermia 显示文摘 | DIETRICH W D ATKINS C M Bramlett H M | 2009 | J Neurotranma2009，26，3： | 1 |
| 4 | Posttraumatic hypothennia is nemopmtective in a model of traumatic brain injury complicated by a secondary insult 显示文摘 | Matshita Y Bramlett HM Alonso O | 2001 | Crit Care Med2001，29，11： | 1 |
| 5 | Changes in trkB-ERK1/2- CREB/Elk-1 pathways in hippocampal mossy fiber organization after traumatic brain injury 显示文摘 | Hu B Liu C Bramlett H | 2004 | Cereb Blood Flow Metab2004，24，8： | 1 |
| 6 | Progressive damage after brain and spinal cord injury:pathomechanisms and treatment strategies显示文摘 | Bramlett HM Dietrich WD | | 0，，： | 1 |
| 7 | Therapeutic hypothermia alters microRNA responses to traumatic brain injury in rats 显示文摘 | Truettner JS Alonsol OF Bramlett HM | 2011 | J Cereb Blood Flow Metab2011，31，9： | 1 |
| 8 | The evidence for hypothermia as a neu- roprotectant in traumatic brain injury 显示文摘 | Dietrich WD Bramlett HM | 2010 | Neurotherapeutics2010，7，1： | 1 |
| 9 | Regulation of carbohydrate metabolism by the farnesoid X receptor显示文摘 | Stayrook KR Bramlett KS Savkur RS Ficorilli J Cook T Christe ME | | 0，，： | 1 |
| 10 | Quantitative structural changes in white and gray matter 1 year following traumatic brain injury in rats显示文摘 | Bramlett HM Dietrich WD | 2002 | Acta Neuropathol2002，103，： | 1 |
| 11 | Implications of loyalty program membership and service experiences for customer retention and value显示文摘 | Ruth N. Bolton P. K. Kannan Matthew D. Bramlett | 2000 | Journal of the Academy of Marketing Science2000，，1： | 1 |
| 12 | Secondary hypoxia following moderate fluid percussion brain injury in rats exacerbates sensorimotor and cognitive deficits显示文摘 | Bramlett HM Dietrich WD Green EJ | 1999 | J Neurotrauma1999，16，11： | 1 |
| 13 | Changes in trkB - ERK1/ 2 - CREB/Elk - 1 pathways in hippocampal mossy fiber organization after traumatic brain injury 显示文摘 | Hu B Li C Bramlett H | 2004 | Cerebral Blood Flow2004，24，8： | 1 |
| 14 | Pulse combustor modeling demonstration of the importance of characteristic times 显示文摘 | Barr P K Keller J O Bramlette T T | 1990 | Combustion andFlame1990，82，34： | 1 |
| 15 | Regulation of carbohydrate metabolism by the farnesoid X receptor显示文摘 | Stayrook KR Bramlett KS Savkur RS Ficorilli J Cook T Christe ME | | 0，，： | 1 |
| 16 | Therapeutic hypothermia alters micro RNA responses to traumatic brain injury in rats显示文摘 | Truettner JS Alonso OF Bramlett HM | 2011 | J Cereb Blood Flow Metab2011，31，： | 1 |
| 17 | Changes in trkB - ERK1 /2 - CREB/Elk- 1 pathways in hippocampal mossy fiber organization after traumatic brain injury显示文摘 | Hu B Liu C Bramlett H | 2004 | J Cereb Blood Flow Metab2004，24，8： | 1 |
| 18 | Pathophysiology of cerebral ischemia and brain trauma: Similarities and differences 显示文摘 | Bramlett HM Dietrich WD | 2004 | J Cereb Blood Flow Metab2004，24，2： | 1 |
| 19 | Pulse combustion: the quantification of characteristic times显示文摘 | Keller J O Bramlette T T Westbrook C K | 1990 | Combustion and Flame1990，79，2： | 1 |
| 20 | The Evidence for Hypothermia as a Neuroprotectant in Traumatic Brain Injury显示文摘 | W. Dalton Dietrich Helen M. Bramlett | 2010 | Neurotherapeutics2010，，1： | 1 |
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