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| 1 | On the mechanical behavior of the human biliary system显示文摘This paper reviews the progress made in understanding the mechanical behaviour of the biliary system. Gallstones and diseases of the biliary tract affect more than 10% of the adult population. The complications of gallstones, i.e. acute pancreatitis and obstructive jandice, can be lethal, and patients with acalculous gallbladder pain often pose diagnostic difficulties and undergo repeated ultrasound scans and oral cholecystograms. Moreover, surgery to remove the gallbladder in these patients, in an attempt to relieve the symptoms, gives variable results. Extensive research has been carried out to understand the physiological and pathological functions of the biliary system, but the mechanism of the pathogenesis of gallstones and pain production still remain poorly understood. It is believed that the mechanical factors play an essential role in the mechanisms of the gallstone formation and biliary diseases. However, despite the extensive literature in clinical studies, only limited work has been carried out to study the biliary system from the mechanical point of view. In this paper, we discuss the state of art knowledge of the fluid dynamics of bile flow in the biliary tract, the solid mechanics of the gallbladder and bile ducts, recent mathematical and numerical modelling of the system, and finally the future challenges in the area. | Xiaoyu Luo Wenguang Li Nigel Bird Swee Boon Chin NA Hill Alan G Johnson | 2007 | World Journal of Gastroenterology2007，13，9： | 9 |
| 2 | Endothelial dysfunction,impaired endogenous fibrinolysis, and cigarette smoking: a mechanism for arterial thrombosis and myocardial infarction显示文摘 | Newby DE Wright RA Labinjoh C Ludlam CA Fox KA Boon NA | 1999 | Circulation1999，99，11： | 1 |
| 3 | Randomized placebo- controlled trial of continuous positive airway pressure on blood pressure in the sleep apnea-hypopnea syndrome 显示文摘 | Faccenda JF Mackay TW Boon NA | 2001 | Am J Respir Crit Care Med2001，163，2： | 1 |
| 4 | Management of upper gastrointestinal haemorrhage complicating dual anti platelet therapy显示文摘 | Henriksen PA Palmer K Boon NA | 2008 | QJM2008，101，4： | 1 |
| 5 | Randomized placebo controlled trial of continuous positive airway pressure on blood pressure in the sleep apnea-hypopnea syndrome显示文摘 | Mackay TW Boon NA | 2001 | Am J Respir Crit Care Med2001，163，： | 1 |
| 6 | Davidson's Principles & Practice of Medicine,20th Edition显示文摘 | BOON NA COLLEDGE NR WALKER BR AND HUNTER JAA | 2006 | Churchill Livingstone2006，，： | 1 |
| 7 | Endothelial fibrinolytic capacity predicts future adverse cardiovascular events in patients with coronary heart disease显示文摘 | Robinson SD Ludlam CA Boon NA | 2007 | Arterioscler Thromb Vasc Biol2007，27，7： | 1 |
| 8 | Calcific aortic stenosis A disease of the valve and the myocardium 显示文摘 | Dweck MR Boon NA Newby DE | 2012 | J Am Coil Cardiol2012，60，19： | 1 |
| 9 | Chronic CD70- driven costimulation impairs IgG responses by instructing T cells to inhibit germinal center B cell formation through FasL- Fas interactions显示文摘 | Beishuizen CR Kragten NA Boon L | 2009 | J Immunol2009，183，10： | 1 |
| 10 | Role of the endo- thelium in the vascular effects of the thrombin receptor( protease - activated receptor type 1 ) in humans 显示文摘 | Gudmundsd6ttir IJ Lang NN Boon NA | 2008 | J Am Coil Cardiol2008，51，18： | 1 |
| 11 | The medical management of valvar heart disease显示文摘 | Boon NA Bloomfield P | 2002 | Heart2002，87，4： | 1 |
| 12 | Management of upper gastrointestinal haemorrhage complicating dual anti-platelet therapy显示文摘 | Henriksen PA Palmer K Boon NA | 2008 | Q J M2008，101，4： | 1 |
| 13 | Thyroid disease and the heart显示文摘 | Toft AD Boon NA | 2000 | Heart2000，84，4： | 1 |
| 14 | Management of upper gastroin- testinal haemorrhage complicating dual anti-platelet therapy 显示文摘 | Henriksen PA Palmer K Boon NA | 2008 | QJM2008，101，4： | 1 |
| 15 | Calcific aortic stenosis:a disease of the valve and the myocardium显示文摘 | Dweck MR Boon NA Newby DE | | 0，，19： | 1 |
| 16 | Head-up tilt testing the balance of evidence显示文摘 | HAG OE BOON NA | 1994 | Br Heart J1994，72，： | 1 |
| 17 | Marked impairment of protease-activated receptor type 1-mediated vasodilation and fibrinolysis in cigarette smokers-Smoking,thrombin,and vascular responses in vivo显示文摘 | Lang NN Guomundsdottir IJ Boon NA | 2008 | J Am Coll Cardiol2008，52，1： | 1 |
| 18 | Randomized placebocontrolled trial of continuous positive airway pressure on blood pressure in the sleep apnea-hypopnea syndrome显示文摘 | Mackay TW Boon NA | 2001 | Am J Respir Crit Care Med2001，163，2： | 1 |
| 19 | Immunopathogenesis of HIV-related heart muscle disease:current perspectives显示文摘 | Currie PF Boon NA | | 0，，1： | 1 |
| 20 | The medical management of valvular heart disease显示文摘 | Bloomfield P | 2002 | Heart2002，87，： | 1 |
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