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26篇 您的检索式:作者名="BlockI"
    题名 作者 年代 出处 被引量
1On uniform estimate in Calabi-Yau theorem显示文摘We show that the uniform estimate in the Calabi-Yau theorem easily follows from the local stability of the complex Monge-Ampere equation.Zbigniew Blocki 2005Science China Mathematics2005,48,z1:2
2Engineering microparticles based on solidified stem cell secretome with an augmented pro-angiogenic factor portfolio for therapeutic angiogenesis显示文摘Tissue (re)vascularization strategies face various challenges, as therapeutic cells do not survive long enough in situ, while the administration of pro-angiogenic factors is hampered by fast clearance and insufficient ability to emulate complex spatiotemporal signaling. Here, we propose to address these limitations by engineering a functional biomaterial capable of capturing and concentrating the pro-angiogenic activities of mesenchymal stem cells (MSCs). In particular, dextran sulfate, a high molecular weight sulfated glucose polymer, supplemented to MSC cul-tures, interacts with MSC-derived extracellular matrix (ECM) components and facilitates their co-assembly and accumulation in the pericellular space. Upon decellularization, the resulting dextran sulfate-ECM hybrid material can be processed into MIcroparticles of SOlidified Secretome (MIPSOS). The insoluble format of MIPSOS protects protein components from degradation, while facilitating their sustained release. Proteomic analysis demonstrates that MIPSOS are highly enriched in pro-angiogenic factors, resulting in an enhanced pro-angiogenic bioactivity when compared to naïve MSC-derived ECM (cECM). Consequently, intravital microscopy of full-thickness skin wounds treated with MIPSOS demonstrates accelerated revascularization and healing, far superior to the ther-apeutic potential of cECM. Hence, the microparticle-based solidified stem cell secretome provides a promising platform to address major limitations of current therapeutic angiogenesis approaches.Thomas Spater Marisa Assunçao Kwok Keung Lit Guidong Gong Xiaoling Wang Yi-Yun Chen Ying Rao Yucong Li Chi Him Kendrick Yiu Matthias W.Laschke Michael D.Menger Dan Wang Rocky S.Tuan Kay-Hooi Khoo Michael Raghunath Junling Guo Anna Blocki 2022Bioactive Materials2022,7,11:1
3Thin C/C Composite Shells for High Energy Physics:Manufacture and Properties显示文摘Blazewicz S Blocki J Chlopek J 1996Carbon1996,34,11:1
4Dynamical Hindrance to Compound-nucleus Formation in Heavy-ion Reactions显示文摘Blocki J P Feldmeier H Swiatecki W J 1986Nucl Phys1986,459,:1
5Not all MSCs can act as pericytes: functional in vitro assays to distinguish pericytes from other mesenchymal stem ceils in angiogenesis 显示文摘Blocki A Wang Y Koch M 2013Stem Ceils Dev2013,22,17:1
6Ship safety in connection with parametric resonance of the roll显示文摘 1980International Shipbuilding Progress1980,,27:1
7Thin C/C composite shells for high energy physics:manufacture and properties显示文摘Blazewicz S Blocki J Cldopek J 1996Carbon1996,34,11:1
8Thin C/Ccomposite shells for high energy physics manufacture andproperties显示文摘Blazewicz S Blocki J Chlopek J 1996Carbon1996,34,11:1
9Nuclear asymmetry energy and isovectorstiffness within the effective surface approximation显示文摘Blocki J P Magner A G 2013PhysicalReview C2013,87,04:1
10Nuclear asymmetry energy and isovector stiffness within the effective surface approximation 显示文摘Blocki J P Magner A G 2013Physical Review C2013,87,04:1
11Some estimates for the Bergman kernel and metric in terms of logarithmic capacity 显示文摘Blocki Z 2007Nagoya Math J2007,185,:1
12Suita conjecture and the Ohsawa- Takegoshi extension theorem 显示文摘Blocki Z 2013Invent Math2013,193,1:1
13Determinationoforganophosphatepesticidesatacarbonnanotube/organophosphorushydrolaseelectrochemicalbiosensor显示文摘DeoR WangJ BlockI 0,,:1
14Applying macromolecular crowding to enhance extracel ular matrix deposition and its remodeling in vitro for tissue engineering and cel-based therapies显示文摘Chen C Loe F Blocki A 0,,4:1
15Effects of age and serum 25-OH-vitamin D on serum parathyroid hormone levels显示文摘Valcour A1 Blocki F Hawkins DM 2012J Clin Endocrinol Metab2012,97,11:1
16Thin C/C composite for high energy physics:manufacture and properties显示文摘BLAZEWICZ S BLOCKI J CHLOPEK J 1996Carbon1996,34,11:1
17Ship safety in connection with parametric resonance of the roll显示文摘BLOCKI W 1980International Shipbuilding Progress1980,37,:1
18Thin C/C composite shells for high energy physics:Manufacture and properties显示文摘 Blocki J Chlopek J 1996Carbon1996,34,11:1
19Thin C/C composite shells for high energy physics:manufacture and properties显示文摘Blazewicz S Blocki J Chlopek J 1996Carbon1996,34,11:1
20Hyperconvexity and Bexgman completeness显示文摘 Pflug P 1998Nagoya Math J1998,151,:1
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