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| 1 | MicroRNA Signature in Metastatic Colorectal Cancer Patients Treated With Anti-EGFR Monoclonal Antibodies显示文摘 | Federico Cappuzzo Andrea Sacconi Lorenza Landi Vienna Ludovini Francesca Biagioni Armida D’Incecco Alessandra Capodanno Jessica Salvini Enrichetta Corgna Samanta Cupini Cecilia Barbara Gabriella Fontanini Lucio Crinò Giovanni Blandino | 2013 | Clinical Colorectal Cancer2013，，： | 3 |
| 2 | Viral hepatitis:Innovations and expectations显示文摘Viral hepatitis is a significant health problem worldwide,associated with morbidity and mortality.Hepatitis B,C,D,and occasionally E viruses(HBV,HCV,HDV,and HEV)can evolve in chronic infections,whereas hepatitis A virus(HAV)frequently produces acute self-limiting hepatitis.In the last years,different studies have been performed to introduce new antiviral therapies.The most important goal in the treatment of viral hepatitis is to avoid chronic liver disease and complications.This review analyzes currently available therapies,in particular for viruses associated with chronic liver disease.The focus is especially on HBV and HCV therapies,investigating new drugs already introduced in clinical practice and clinical trials.We also describe new entry inhibitors,developed for the treatment of chronic HDV and HBV and currently available treatments for HEV.The last drugs introduced have shown important efficacy in HCV,with achievable target HCV elimination by 2030.Concurrently,renewed interest in curative HBV therapies has been registered;current nucleotide/nucleoside analogs positively impact liver-related complications,ensuring high safety and tolerability.Novel approaches to HBV cure are based on new antivirals,targeting different steps of the HBV life cycle and immune modulators.The improved knowledge of the HDV life cycle has facilitated the development of some direct-acting agents,as bulevirtide,the first drug conditionally approved in Europe for HDV associated compensated liver disease.Further studies are required to identify a new therapeutic approach in hepatitis E,especially in immunosuppressed patients. | Simona Leoni Alberto Casabianca Benedetta Biagioni Ilaria Serio | 2022 | World Journal of Gastroenterology2022，28，5： | 3 |
| 3 | Relevance of apolipoprotein e 4 for the lipid profile of Brazilian patients with coronary artery disease 显示文摘 | Souza DR Nakachima L Biagioni RB | 2007 | Braz J Med Biol Res2007，40，2： | 1 |
| 4 | Induction of the Wnt inhibitor,Dickkopf-1,is associated with neurodegeneration related to temporal lobe epilepsy显示文摘 | BUSCETI CL BIAGIONI F ARONICA E | 2007 | Epilepsia2007，48，4： | 1 |
| 5 | Relevance of apolipoprotein E4 for the lipid profile of Brazilian patients with coronary artery disease显示文摘 | Souza DR Nakachima L Biagioni RB | 2007 | Braz J Med Biol Res2007，40，2： | 1 |
| 6 | Occiptal sawtooth:a physiological EEG pattern in very premature infants显示文摘 | Biagioni E Frisone MF Laroche S | 2000 | Clin Neurophysiol2000，111，12： | 1 |
| 7 | Thermal changes observed at implant sites during internal and external irrigation显示文摘 | Benington IC Biagioni PA Briggs J | 2002 | Clin Oral Implants Res2002，13，3： | 1 |
| 8 | A comparative study of the efficacy of Aphtheal in the management of recurrent minor aphthous ulceration 显示文摘 | Murray B McGuinnessN Biagioni P | 2005 | Oral Pathol Med2005，34，7： | 1 |
| 9 | Rapamycin inhibits the growth of glioblastoma显示文摘 | Arcella A Biagioni F Antonietta Oliva M | 2013 | Brain Res2013，1495，： | 1 |
| 10 | The efficacy of amlexanox Oradisc on the prevention of recurrent minor aphthons ulceration显示文摘 | B Murray P A Biagioni P J Lamey | 2006 | J Oral Pathol Med2006，35，： | 1 |
| 11 | Relevalice of apolipoprotcin E4 for the lipid profile of Brazilian patieilts with coronary artery disease显示文摘 | Souza DR Nakachima l Biagioni RB | 2007 | Hraz J Med Bio[ Res2007，40，2： | 1 |
| 12 | Plasmonic mid-infrared third harmonic generation in germanium nanoantennas显示文摘We demonstrate third harmonic generation in plasmonic antennas consisting of highly doped germanium grown on silicon substrates and designed to be resonant in the mid-infrared frequency range that is inaccessible with conventional nonlinear plasmonic materials.Owing to the near-field enhancement,the result is an ultrafast,subdiffraction,coherent light source with a wavelength tunable between 3 and 5μm,and ideally overlapping with the fingerprint region of molecular vibrations.To observe the nonlinearity in this challenging spectral window,a highpower femtosecond laser system equipped with parametric frequency conversion in combination with an all-reflective confocal microscope setup is employed.We demonstrate spatially resolved maps of the linear scattering cross section and the nonlinear emission of single isolated antenna structures.A clear third-order power dependence as well as mid-infrared emission spectra prove the nonlinear nature of the light emission.Simulations support the observed resonance length of the double-rod antenna and demonstrate that the field enhancement inside the antenna material is responsible for the nonlinear frequency mixing. | Marco P.Fischer Aaron Riede Kevin Gallacher Jacopo Frigerio Giovanni Pellegrini Michele Ortolani Douglas J.Paul Giovanni Isella Alfred Leitenstorfer Paolo Biagioni Daniele Brida | 2018 | Light(Science & Applications)2018，7，1： | 1 |
| 13 | A maturation of cerebral electrical activity and development of cortical folding in young very preterm infants显示文摘 | Biagioni E Frisone MF Laroche S Kapetanakis BA Ricci D Adeyi-Obe M | 2007 | Clinical Neurophysiology2007，118，1： | 1 |
| 14 | MicroRNAs: short non-codingplayere in cancer chemoresistance 显示文摘 | Donzelli S Mori F Biagioni F ef al | 2014 | Mol Cell Ther2014，2，： | 1 |
| 15 | miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer显示文摘 | Sacconi A Biagioni F Canu V | 2012 | Cell Death Dis2012，3，： | 1 |
| 16 | Adaptive subcarrier allocation schemes for wireless OFDMA systems in WiMAX networks显示文摘 | Biagioni A Fantacci R Marabissi D | 2009 | IEEE Journal on Selected Areas in Communication2009，27，2： | 1 |
| 17 | Induction of the Wnt antagonist, Dickkopf-1, contributes to the development of neuronal death in models of brain focal ischemia 显示文摘 | Mastroiacovo F Busceti CL Biagioni F | 2009 | J Cereb Blood Flow Metab2009，29，： | 1 |
| 18 | miR‐10b*, a master inhibitor of the cell cycle, is down‐regulated in human breast tumours显示文摘 | Francesca Biagioni Noa Bossel Ben‐Moshe Giulia Fontemaggi Valeria Canu Federica Mori Barbara Antoniani Anna Di Benedetto Raffaela Santoro Sabrina Germoni Fernanda De Angelis Anna Cambria Roi Avraham Giuseppe Grasso Sabrina Strano Paola Muti Marcella Motto | 2012 | EMBO Mol Med2012，，11： | 1 |
| 19 | Induction of the Wnt antagonist,Dickkopf-1,contributes to the development of neuronal death in models of brain focal ischemia显示文摘 | Mastroiacovo F Busceti CL Biagioni F et a1 | 2009 | J Cereb Blood Flow Metab2009，29，2： | 1 |
| 20 | The matrix metalloproteinase inhibitor marimastat promotes neural progenitor cell differentiation into neurons by gelatinaseindependent TIMP-2-dependent mechanisms显示文摘 | Sinno M Biagioni S Ajmone-Cat MA | 2013 | Stem Cells Dev2013，22，3： | 1 |
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