|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Gut microbiome in acute pancreatitis:A review based on current literature显示文摘The gut microbiome is a complex microbial community,recognized for its potential role in physiology,health,and disease.The available evidence supports the role of gut dysbiosis in pancreatic disorders,including acute pancreatitis(AP).In AP,the presence of gut barrier damage resulting in increased mucosal permeability may lead to translocation of intestinal bacteria,necrosis of pancreatic and peripancreatic tissue,and infection,often accompanied by multiple organ dysfunction syndrome.Preserving gut microbial homeostasis may reduce the systemic effects of AP.A growing body of evidence suggests the possible involvement of the gut microbiome in various pancreatic diseases,including AP.This review discusses the possible role of the gut microbiome in AP.It highlights AP treatment and supplementation with prebiotics,synbiotics,and probiotics to maintain gastrointestinal microbial balance and effectively reduce hospitalization,morbidity and mortality in an early phase.It also addresses novel therapeutic areas in the gut microbiome,personalized treatment,and provides a roadmap of human microbial contributions to AP that have potential clinical benefit. | Bharati Kadamb Patel Kadamb H Patel Madhav Bhatia Shridhar Ganpati Iyer Krishnakumar Madhavan Shabbir M Moochhala | 2021 | World Journal of Gastroenterology2021，27，30： | 10 |
| 2 | Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation. | Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon | 2012 | World Journal of Gastrointestinal Oncology2012，4，5： | 5 |
| 3 | Inflammatory mediators in acute pancreatitis显示文摘 | Bhatia M Brady M | 2000 | J Pathol2000，190，2： | 2 |
| 4 | Anatomical variations in the branches of the human aortic arch:a recent study of a South Australian population显示文摘 | Bhatia K Ghabriel MN Henneberg M | 2005 | Folia Morphol(Warsz)2005，64，3： | 1 |
| 5 | Favorable clinical outcomes of three-dimensional computer-optimized high-dose-rate prostate brachytherapy in the management of localized prostate cancer显示文摘 | Yamada Y Bhatia S Zaider M | 2006 | Brachytherapy2006，5，： | 1 |
| 6 | Hypoxia regulates insulin-like growth factor-binding protein 1 in human fetal hepatocytes in primary culture:suggestive molecular mechanisms for in utero fetal growth restriction caused by uteroplacental insufficiency显示文摘 | Popovici RM Lu M Bhatia S | 2001 | J Clin Endocrinol Metab2001，86，6： | 1 |
| 7 | Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome显示文摘 | Bhatia M Moochhala S | 2004 | J Pathol2004，202，2： | 1 |
| 8 | Immunoglobulin G and complement C3 levels in pregnancy induced hypertension显示文摘 | Ramdenee G R Matah M Bhatia B D | 1996 | Indian Pediatr1996，32，2： | 1 |
| 9 | Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis显示文摘 | Zhang H Moochhala S M Bhatia M | 2008 | J Immunol2008，181，6： | 1 |
| 10 | Cement leakage in percutaneous vertebroplasty:effect of preinjection gelfoam embolization显示文摘 | Bhatia C Barzilay Y Krishna M | 2006 | Spine (Phila Pa 1976)2006，31，8： | 1 |
| 11 | JNK1/2 regulates ER-mito- chondrial Ca2+ cross-talk during IL-1β-mediated cell death in RINm5F and human primary β-cells显示文摘 | Verma G Bhatia H Datta M | 2013 | Mol Biol Cell2013，24，12： | 1 |
| 12 | Inflammatory response on the pancreatic acinar cell injury显示文摘 | Bhatia M | 2005 | Scand J Surg2005，94，2： | 1 |
| 13 | Development and validation of a new technique for ultrasound-guided stellate ganglion block显示文摘 | Gofeld M Bhatia A Abbas S | 2009 | Reg Anesth Pain Med2009，34，5： | 1 |
| 14 | Sleep disorder in Parkinson's disease显示文摘 | Kumar S Bhatia M Behari M | 2002 | Mov Disord2002，17，： | 1 |
| 15 | Keratomalacia in a neonate secondary to maternal vitamin A deficiency显示文摘 | Gupta M Jora R Bhatia R | 2005 | Indian J Pedi-art2005，72，10： | 1 |
| 16 | Role of inflamma--tory mediators in thepatho- physiology of a--cute respiratory distress syndrome显示文摘 | Bhatia M Moochhala S | 2004 | JPathol2004，202，2： | 1 |
| 17 | Inflammatory mediators in acut epancreatitis 显示文摘 | Bhatia M Brady M Shokuhi S | 2009 | J Pathol2009，190，2： | 1 |
| 18 | Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse显示文摘 | Li L Bhatia M Zhu Y Z | 2005 | FASEB2005，19，9： | 1 |
| 19 | Trace element characteristics of greywackes and tectonic setting discrimination of sedimentary basins显示文摘 | BHATIA M R and CROOK K A W | 1986 | Contrib Mineral Petrol1986，92，： | 1 |
| 20 | Trace element characteristics of grey- wacke and tectonic setting discrimination of sedimentary basins 显示文摘 | Bhatia M R Crook K A W | 1986 | Contributions to Mineralogy and Petrology1986，92，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员