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| 1 | Correlation of endoscopic disease severity with pediatric ulcerative colitis activity index score in children and young adults with ulcerative colitis显示文摘AIM To investigate of pediatric ulcerative colitis activity index(PUCAI) in ulcerative colitis correlate with mucosal inflammation and endoscopic assessment of disease activity(Mayo endoscopic score).METHODS We reviewed charts from ulcerative colitis patients who had undergone both colonoscopy over 3 years. Clinical assessment of disease severity within 35 d(either before or after) the colonoscopy were included. Patients were excluded if they had significant therapeutic interventions(such as the start of corticosteroids or immunosuppressive agents) between the colonoscopy and the clinical assessment. Mayoendoscopic score of the rectum and sigmoid were done by two gastroenterologists. Inter-observer variability in Mayo score was assessed.RESULTS We identified 99 patients(53% female, 74% pancolitis) that met inclusion criteria. The indications for colonoscopy included ongoing disease activity(62%), consideration of medication change(10%), assessment of medication efficacy(14%), and cancer screening(14%). Based on PUCAI scores, 33% of patients were in remission, 39% had mild disease, 23% had moderate disease, and 4% had severe disease. There was 'moderate-substantial' agreement between the two reviewers in assessing rectal Mayo scores(kappa = 0.54, 95%CI: 0.41-0.68). CONCLUSION Endoscopic disease severity(Mayo score) assessed by reviewing photographs of pediatric colonoscopy has moderate inter-rater reliability, and agreement was less robust in assessing patients with mild disease activity. Endoscopic disease severity generally correlates with clinical disease severity as measured by PUCAI score. However, children with inflamed colons can have significant variation in their reported clinical symptoms. Thus, assessment of both clinical symptoms and endoscopic disease severity may be required in future clinical studies. | Basavaraj Kerur Heather J Litman Julia Bender Stern Sarah Weber Jenifer R Lightdale Paul A Rufo Athos Bousvaros | 2017 | World Journal of Gastroenterology2017，23，18： | 5 |
| 2 | CDMA/HDR: A bandwidth-efficient high-speed wireless data service for nomadic users 显示文摘 | P Bender P Black M Grob R Padovani N Sindhushayana A Viterbi | 2000 | IEEE Communication Magazine (S0733-8716)2000，38，7： | 1 |
| 3 | Real-case simulations of hurricane-ocean interaction using a high-resolution coupled model: effects on hurricane intensity显示文摘 | BENDER M A GINIS I | 2000 | Monthly Weather Review2000，128，4： | 1 |
| 4 | Preconditions to ground based GPS water vapour tomography显示文摘 | Bender M and Raabe A | 2007 | Annales Geophysicae2007，25，8： | 1 |
| 5 | Plant species diversity of homegardens of Cuba and its significance for household food supply显示文摘 | Wezel A Bender S | 2003 | Agroforest Syst2003，57，1： | 1 |
| 6 | Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood 显示文摘 | Bender A Sapp M Schuler G | 1996 | Immunol Methods1996，196，2： | 1 |
| 7 | Alanine Catabolism in Klebsiella aerogenes: Molecular Characterization of the dadAB Operon and Its Regulation by the Nitrogen Assimilation Control Protein显示文摘 | Brian K Janes Robert A Bender | 1998 | Journal of Bacteriology1998，180，3： | 1 |
| 8 | Continuous High-Frequency Dissolved O-2/Ar Measurements by Equilibrator Inlet Mass Spectrometry 显示文摘 | Cassar N Barnett B A Bender M L | 2009 | Analytical Chemistry2009，81，5： | 1 |
| 9 | A numerical study of t he effect of a mountain range on a landfalling tropical cyclone显示文摘 | BENDER M A TULETA R E KURIHARA Y | 1985 | Mon Wea Rev1985，113，4： | 1 |
| 10 | Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule 显示文摘 | Bender E Buist A Jurzak M | 2002 | Proc Natl Acad Sci USA2002，99，： | 1 |
| 11 | Early oxidation of organic matter in pelagic sediments of the eastern equatorial Atlantic: suboxic diagenesis 显示文摘 | Froelieh P N Klinkhammer G P Bender M L Luedtke N A Heath G R Cullen D Dauphin P Hammond D Hartman B | 1979 | Geoehim Cosmoehim Acta1979，43，7： | 1 |
| 12 | PT-symmetric versus Hermitian formulations of quantum mechanics显示文摘 | BENDER C M CHEN Junhua MILTON K A | | 0，，： | 1 |
| 13 | Serratia marcescens quinoprotein glucose dehydrogenase activity mediates medium aciditication and inhibition of prodigiosin production by glucose显示文摘 | JFENDER J E BENDER C M STELLA N A | 2012 | Applied and Environmental Microbology2012，78，17： | 1 |
| 14 | Modeling of dry sliding friction dynamics: From heuristic model to physically motivated models and back显示文摘 | BENDER F A LAMPAERT V SWEVERS J | 2004 | Chaos2004，14，2： | 1 |
| 15 | Synthesis and structure-activity relationship of novel 6-aryl-1,4-dihydrobeuzo oxazine -2-thiones as progesterone receptor modulators leading to the potent and selective nonsteroidal progesterone receptor agonist tanaproget显示文摘 | FENSOME A BENDER R CHOPRA R | 2005 | J Med Chem2005，48，16： | 1 |
| 16 | Living with death:The evolution of the mitochondrial pathway of apoptosis in animals显示文摘 | Oberst A Bender C Green DR | 2008 | Cell Death Differ2008，15，7： | 1 |
| 17 | Preservation of chopped sweet sorghum using sulfur dioxide显示文摘 | Eckhoff S R Bender D A | 1985 | Transactions of The ASAE1985，28，2： | 1 |
| 18 | Eleetrospun ceramic fibers: composition, structure and the fate of precursors 显示文摘 | Turtle R W Chowdury A Bender E T | 2008 | Appl Surf Sci2008，254，16： | 1 |
| 19 | Aggressive confusional state as a clinical manifestation of status epilepticus in MELAS显示文摘 | Feddersen B Bender A Arnold S | 2003 | Neurology2003，61，： | 1 |
| 20 | Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood显示文摘 | BENDER A SAPP M SCHULER G | 1996 | J Immunol Methods1996，196，2： | 1 |
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