|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Does heart rate variability correlate with long-term prognosis in myocardial infarction patients treated by early revascularization?显示文摘AIM To assess the prevalence of depressed heart rate variability(HRV) after an acute myocardial infarction(MI),and to evaluate its prognostic significance in the present era of immediate reperfusion.METHODS Time-domain HRV(obtained from 24-h Holter recordings) was assessed in 326 patients(63.5 ± 12.1 years old; 80% males),two weeks after a complicated MI treated by early reperfusion: 208 ST-elevation myocardial infarction(STEMI) patients(in which reperfusion wassuccessfully obtained within 6 h of symptoms in 94% of cases) and 118 non-ST-elevation myocardial infarction(NSTEMI) patients(percutaneous coronary intervention was performed within 24 h and successful in 73% of cases). Follow-up of the patients was performed via telephone interviews a median of 25 mo after the index event(95%CI of the mean 23.3-28.0). Primary endpoint was occurrence of all-cause or cardiac death; secondary end-point was occurrence of major clinical events(MCE,defined as mortality or readmission for new MI,new revascularization,episodes of heart failure or stroke). Possible correlations between HRV parameters(mainly the standard deviation of all normal RR intervals,SDNN),clinical features(age,sex,type of MI,history of diabetes,left ventricle ejection fraction),angiographic characteristics(number of coronary arteries with critical stenoses,success and completeness of revascularization) and long-term outcomes were analysed.RESULTS Markedly depressed HRV parameters were present in a relatively small percentage of patients: SDNN < 70 ms was found in 16% and SDNN < 50 ms in 4% of cases. No significant differences were present between STEMI and NSTEMI cases as regards to their distribution among quartiles of SDNN(χ~2 =1.536,P = 0.674). Female sex and history of diabetes maintained a significant correlation with lower values of SDNN at multivariate Cox regression analysis(respectively: P = 0.008 and P = 0.008),while no correlation was found between depressed SDNN and history of previous MI(P = 0.999) or number of diseased coronary arteries(P = 0.428) or unsuccessful percutaneous coronary intervention(PCI)(P = 0.691). Patients with left ventricle ejection fraction(LVEF) < 40% presented more often SDNN values in the lowest quartile(P < 0.001). After > 2 years from infarction,a total of 10 patients(3.1%) were lost to follow-up. Overall incidence of MCE at follow-up was similar between STEMI and NSTEMI(P = 0.141),although all-cause and cardiac mortality were higher among NSTEMI cases(respectively: 14% vs 2%,P = 0.001; and 10% vs 1.5%,P = 0.001). The Kaplan-Meier survival curves for all-cause mortality and for cardiac deaths did not reveal significant differences between patients with SDNN in the lowest quartile and other quartiles of SDNN(respectively: P = 0.137 and P = 0.527). Also the MCE-free survival curves were similar between the group of patients with SDNN in the lowest quartile vs the patients of the other SDNN quartiles(P = 0.540),with no difference for STEMI(P = 0.180) or NSTEMI patients(P = 0.541). By the contrary,eventsfree survival was worse if patients presented with LVEF < 40%(P = 0.001).CONCLUSION In our group of patients with a recent complicated MI,abnormal autonomic parameters have been found with a prevalence that was similar for STEMI and NSTEMI cases,and substantially unchanged in comparison to what reported in the pre-primary-PCI era. Long-term outcomes did not correlate with level of depression ofHRV parameters recorded in the subacute phase of the disease,both in STEMI and in NSTEMI patients. These results support lack of prognostic significance of traditional HRV parameters when immediate coronary reperfusion is utilised. | Leonida Compostella Nenad Lakusic Caterina Compostella Li Van Stella Truong Sabino Iliceto Fabio Bellotto | 2017 | World Journal of Cardiology2017，9，1： | 9 |
| 2 | Plasma markers of en dothelial dysfunction in pulmonary hypertension显示文摘 | Bellotto F Tona F | 2001 | Chest2001，120，4： | 1 |
| 3 | Hydrotalcite decomposition mechanism:a clue to the structure and reactivity of spine-like mixed oxides显示文摘 | REBOURS B KLAUSE O | 1996 | J Phys Chem1996，100，2： | 1 |
| 4 | Subcellular electrolyte alterations during progressive hypoxia following reoxygenation in isolated neonatal rat ventricular myocytes显示文摘 | Thandroyen FT Bellotto D Katayama A | 1992 | Circ Res1992，71，1： | 1 |
| 5 | Preparation and characterization of hexaaluminate-based materials for catalytic combustion显示文摘 | Groppi G Bellotto M Cristiani C | 1993 | Applied Catalysis A:General1993，104，： | 1 |
| 6 | Effective immunosuppressive therapy in a patient with primary pulmonary hypertension 显示文摘 | Bellotto F Chiavacci P Laveder F | 1999 | Thorax1999，54，： | 1 |
| 7 | Multisensor-based human detection and tracking for mobile service robots显示文摘 | Bellotto N Hu H | 2009 | IEEE Transactions on Systems Man and Cybernetics-Part B: Cybernetics2009，39，1： | 1 |
| 8 | Preparation and characterization of hexaaluminate-based materials for catalytic combustion显示文摘 | GROPPI G BELLOTTO M CRISTIAM C | 1993 | Appl Catal A1993，104，2： | 1 |
| 9 | On the crystal structure and cation valence of Mn in Mn-substituted Ba-β-Al2O3显示文摘 | BELLOTTO M ARTIOLI G CRISTIANI C | 1998 | J Catal1998，179，2： | 1 |
| 10 | Advances in the Scintillation Performance of LuYAG: Ce Single Crystals 显示文摘 | Kuntner C Auffray E Bellotto D | 2005 | Nuclear Instruments and Methods in Physics Research A2005，537，12： | 1 |
| 11 | Hydrotalcite decomposition mechanism: a clue to the structure and reactivity of spinel- like mixed oxides显示文摘 | Bellotto M Rebours B Clause O | 1996 | Phys Chem1996，100，20： | 1 |
| 12 | Hydrotaleite decomposition mechanism: a clue to the structure and reactivity of spinel-like mixed oxides 显示文摘 | Bellotto M | 1996 | J Phys Chem1996，，100： | 1 |
| 13 | Improvements in calibation procedures for the quantitative determination of trace elements in carhonate material (mussel shells )by laser ablation ICP-MS显示文摘 | Bellotto V R Miekelev N | 2000 | Fresenius Journal of Analytical Chemistry2000，367，7： | 1 |
| 14 | Are- examination of hydrotalcite crystal chemistry 显示文摘 | BELLOTTO M REBOURS B CLAUSE O | 1996 | J Phys Chem1996，100，： | 1 |
| 15 | Plasma markers of endothelial dys-functionin pulmonary hypertension显示文摘 | Cella G Bellotto F TonaF | | 0，，04： | 1 |
| 16 | Methylation of cytosines in nonconventional methylation acceptor sites can contribute to reduced gene expression显示文摘 | Dieguez M J Bellotto M Afsar K | 1997 | Mol Gen Genet1997，253，5： | 1 |
| 17 | Trace metals in mussel shells and corresponding soft tissue samples: a validation experiment for the use of Perna perna shells in pollution monitoring显示文摘 | Bellotto V R Miekeley N | 2007 | Analytical and Bioanalytical Chemistry2007，389，： | 1 |
| 18 | Fatty diabetic lung:al tered alveolar structure and surfaetant protein expression显示文摘 | Foster D J Ravikumar P Bellotto D J | 2010 | Am J PhysiolLungCellMolPhysiol2010，298，3： | 1 |
| 19 | Plasma markers of endothelial dysfunction in pulmonary hypertension 显示文摘 | Celia G Bellotto F Tona F | 2001 | Chest2001，120，4： | 1 |
| 20 | Fatty diabetic lung: altered alveolar structure and surfactant protein expression显示文摘 | Foster DJ Ravikumar P Bellotto DJ | 2010 | Am J Physiol Lung Cell Mol Physiol2010，298，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员