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| 1 | Influence of vitamin D on liver fibrosis in chronic hepatitis C: A systematic review and meta-analysis of the pooled clinical trials data显示文摘AIM To investigate the relationship between vitamin D and liver fibrosis in hepatitis C-monoinfected or hepatitis C virus(HCV)-human immunodeficiency virus(HIV) coinfected patients. METHODS Pertinent studies were located by a library literature search in PubM ed/Embase/Cochrane/Scopus/LILACS by two individual reviewers. Inclusion criteria:(1) studies with patients with HCV or co-infected HCV/HIV;(2) studies with patients ≥ 18 years old;(3) studies that evaluated liver fibrosis stage, only based on liver biopsy; and(4) studies that reported serum or plasma 25(OH)D levels. Studies that included pediatric patients, other etiologies of liver disease, or did not use liver biopsy for fibrosis evaluation, or studies with inadequate data were excluded. Estimated measures of association reported in the literature, as well as corresponding measures of uncertainty, were recorded and corresponding odds ratios with 95%CI were included in a meta-analysis. RESULTS The pooled data of this systematic review showed that 9 of the 12 studies correlated advanced liver disease defined as a Metavir value of F3/4 with 25(OH) D level insufficiency. The meta-analysis indicated a significant association across studies.CONCLUSION Low vitamin D status is common in chronic Hepatitis C patients and is associated with advanced liver fibrosis. | Alia S Dadabhai Behnam Saberi Katie Lobner Russell T Shinohara Gerard E Mullin | 2017 | World Journal of Hepatology2017，9，5： | 6 |
| 2 | Vitamin D levels do not predict the stage of hepatic fibrosis in patients with non-alcoholic fatty liver disease: A PRISMA compliant systematic review and meta-analysis of pooled data显示文摘AIM To investigate the relationship between 25-hydroxyvitamin D [25(OH)D] levels and fibrosis stage in patients with non-alcoholic fatty liver disease(NAFLD).METHODS Two individual reviewers identified relevant studies using the Pub Med, EMBASE, Cochrane, and Scopus databases. Inclusion criteria were as follows:(1) Studies that evaluated adults with NAFLD and serum or plasma 25(OH)D levels; and(2) assessed fibrosis stage using liver biopsy. A rigorous analysis yielded six articles as having sufficient data to employ in evaluating the association of serum vitamin D levels in patients with NAFLD based on their liver fibrosis stage by histopathological analysis. The lead investigators of each of the six studies were contacted and the data were collected. To meta-analyze vitamin D levels in F0-F2 vs F3-F4 fibrosis, a random-effects meta-analysis fit using restricted maximum likelihood was applied. To examine trends across each stage of fibrosis with respect to vitamin D levels, a meta-regression was performed. P < 0.05 was considered statistically significant. RESULTS A total of 937 subjects from six studies were included in the final analysis to evaluate the association of serum vitamin D levels in patients with NAFLD based on their liver fibrosis stage by histopathological analysis. The lead investigators of each of the six studies were contacted and the data were collected. First, the investigators performed a meta-analysis to compare serum vitamin D levels in patients with NAFLD with stage F0-F2 compared to F3-F4, which did not show significance [meta-estimate of the pooled mean difference =-0.86, P = 0.08(-4.17, 2.46)]. A metaregression evaluation of serum vitamin 25(OH)D levels across the individual stages(F0-F4) of fibrosis did not show an association for the six included studies.CONCLUSION Low vitamin D status is not associated with higher stages of liver fibrosis in patients with NAFLD. | Behnam Saberi Alia S Dadabhai Julie Nanavati Lin Wang Russell T Shinohara Gerard E Mullin | 2018 | World Journal of Hepatology2018，10，1： | 3 |
| 3 | Reliable Design of aLogistics Network under Uncertainty : A Fuzzy Possibilitic-queuing Model显示文摘 | Behnam V Reza T M Fariborz J | 2013 | Applied Mathematical Modeling2013，，37： | 1 |
| 4 | Volume rendering on non-regular grids显示文摘 | Behnam T Emanuela A | 1994 | In: Proceedings of EURO Graphics1994，13，3： | 1 |
| 5 | Parametric study of tip clearance casing treatment on performance and stability of a transonic axial compressor显示文摘 | Behnam H B Joao A T Paul C | 2004 | ASME2004，126，4： | 1 |
| 6 | An improved Max-Log-MAP algorithm for turbo decoding and turbo equalization显示文摘 | Shahram T Leila S Behnam S | 2007 | IEEE Trans Instru Measure2007，56，3： | 1 |
| 7 | Parametric study of tip clearance-casing treatment on performance and stability of a transonic axial compressor显示文摘 | Behnam H B Joao A T Paul C I | 2004 | Journal of Turbomach- inery2004，126，4： | 1 |
| 8 | Reliable design of a logis- tics network under uncertainty: A fuzzy possibilitic - queuing model 显示文摘 | BEHNAM V REZA T M FARIBORZ J | 2013 | Applied Mathematical Modeling2013，，37： | 1 |
| 9 | Gallic acid prevents memory deficits and oxidative stress in- duced by intracerebroventricular injection of streptozo- tocin in rats显示文摘 | Mansouri M T Behnam B N Farbood Y | 2013 | Pharmacol Biochem Behavior2013，111，： | 1 |
| 10 | Parametric study of tip clearance casing treatment on performance and stability of a transonic axial compressor显示文摘 | Behnam H B Joao A T Paul C | 2004 | ASME2004，126，： | 1 |
| 11 | Non-covalent func- tionalization of single-walled carbon nanotubes with modified potyethyleneimines for efficient gene delivery显示文摘 | Behnam B Shier W T Nia A H | 2013 | Int J Phar- maceutics2013，454，1： | 1 |
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